DNA damage response and MCL-1 destruction initiate apoptosis in adenovirus-infected cells
about
Hypoxia and defective apoptosis drive genomic instability and tumorigenesisProteasome inhibitors induce apoptosis in human lung cancer cells through a positive feedback mechanism and the subsequent Mcl-1 protein cleavageInteraction of F1L with the BH3 domain of Bak is responsible for inhibiting vaccinia-induced apoptosisProapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins.IBRDC2, an IBR-type E3 ubiquitin ligase, is a regulatory factor for Bax and apoptosis activationThe vaccinia virus protein F1L interacts with Bim and inhibits activation of the pro-apoptotic protein BaxMAP-1 is a mitochondrial effector of Bax.The fast-mobility isoform of mouse Mcl-1 is a mitochondrial matrix-localized protein with attenuated anti-apoptotic activityThe Bcl-2 apoptotic switch in cancer development and therapymir-29 regulates Mcl-1 protein expression and apoptosisAn internal EELD domain facilitates mitochondrial targeting of Mcl-1 via a Tom70-dependent pathwayThe ubiquitin-proteasome system and cardiovascular diseaseMatrix and backstage: cellular substrates for viral vaccinesBim and Bmf synergize to induce apoptosis in Neisseria gonorrhoeae infectionStapled BH3 peptides against MCL-1: mechanism and design using atomistic simulationsStructural insights into the degradation of Mcl-1 induced by BH3 domainsA novel BH3 ligand that selectively targets Mcl-1 reveals that apoptosis can proceed without Mcl-1 degradationEvidence that inhibition of BAX activation by BCL-2 involves its tight and preferential interaction with the BH3 domain of BAXStabilization and enhancement of the antiapoptotic activity of mcl-1 by TCTPBH3-ligand regulates access of MCL-1 to its E3 ligaseThe AAA-ATPase p97 is essential for outer mitochondrial membrane protein turnoverMcl-1 is a key regulator of apoptosis resistance in Chlamydia trachomatis-infected cellsUp-regulation of Mcl-1 and Bak by coronavirus infection of human, avian and animal cells modulates apoptosis and viral replicationThr 163 phosphorylation causes Mcl-1 stabilization when degradation is independent of the adjacent GSK3-targeted phosphodegron, promoting drug resistance in cancerThe mitochondrial protein Bak is pivotal for gliotoxin-induced apoptosis and a critical host factor of Aspergillus fumigatus virulence in miceBim/Bcl-2 balance is critical for maintaining naive and memory T cell homeostasisModulation of Mcl-1 expression reduces age-related cochlear degenerationAge-related changes in the ratio of Mcl-1/Bax expression in the rat cochlea.Interaction between MYC and MCL1 in the genesis and outcome of non-small-cell lung cancer.Phase I study of obatoclax mesylate (GX15-070), a small molecule pan-Bcl-2 family antagonist, in patients with advanced chronic lymphocytic leukemia.Nitric oxide induces cell death by regulating anti-apoptotic BCL-2 family members.On to the road to degradation: atherosclerosis and the proteasomeDynamic changes in Mcl-1 expression regulate macrophage viability or commitment to apoptosis during bacterial clearanceAcquired resistance to ABT-737 in lymphoma cells that up-regulate MCL-1 and BFL-1.A cardinal role for cathepsin d in co-ordinating the host-mediated apoptosis of macrophages and killing of pneumococci.Perturbation of the Bcl-2 network and an induced Noxa/Bcl-xL interaction trigger mitochondrial dysfunction after DNA damageMcl-1 ubiquitination: unique regulation of an essential survival protein.Ionizing radiation sensitizes breast cancer cells to Bcl-2 inhibitor, ABT-737, through regulating Mcl-1Pseudomonas exotoxin A-mediated apoptosis is Bak dependent and preceded by the degradation of Mcl-1MicroRNA-125b confers the resistance of breast cancer cells to paclitaxel through suppression of pro-apoptotic Bcl-2 antagonist killer 1 (Bak1) expression.
P2860
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P2860
DNA damage response and MCL-1 destruction initiate apoptosis in adenovirus-infected cells
description
2003 nî lūn-bûn
@nan
2003 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
DNA damage response and MCL-1 destruction initiate apoptosis in adenovirus-infected cells
@ast
DNA damage response and MCL-1 destruction initiate apoptosis in adenovirus-infected cells
@en
DNA damage response and MCL-1 destruction initiate apoptosis in adenovirus-infected cells
@nl
type
label
DNA damage response and MCL-1 destruction initiate apoptosis in adenovirus-infected cells
@ast
DNA damage response and MCL-1 destruction initiate apoptosis in adenovirus-infected cells
@en
DNA damage response and MCL-1 destruction initiate apoptosis in adenovirus-infected cells
@nl
prefLabel
DNA damage response and MCL-1 destruction initiate apoptosis in adenovirus-infected cells
@ast
DNA damage response and MCL-1 destruction initiate apoptosis in adenovirus-infected cells
@en
DNA damage response and MCL-1 destruction initiate apoptosis in adenovirus-infected cells
@nl
P2093
P2860
P356
P1433
P1476
DNA damage response and MCL-1 destruction initiate apoptosis in adenovirus-infected cells
@en
P2093
Andrea Cuconati
Chandreyee Mukherjee
Denise Perez
P2860
P304
P356
10.1101/GAD.1156903
P50
P577
2003-11-21T00:00:00Z