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Modeling hippocampal neurogenesis using human pluripotent stem cells.

Modeling hippocampal neurogenesis using human pluripotent stem cells.

http://www.wikidata.org/entity/Q38460557

about

A Dishful of a Troubled Mind: Induced Pluripotent Stem Cells in Psychiatric Research Induced Pluripotent Stem Cells as a Novel Tool in Psychiatric Research Using Patient-Derived Induced Pluripotent Stem Cells to Model and Treat Epilepsies Generation of functional hippocampal neurons from self-organizing human embryonic stem cell-derived dorsomedial telencephalic tissue.From "directed differentiation" to "neuronal induction": modeling neuropsychiatric disease Neuroplasticity and Clinical Practice: Building Brain Power for Health High-throughput compound evaluation on 3D networks of neurons and glia in a microfluidic platform Creating Patient-Specific Neural Cells for the In Vitro Study of Brain Disorders.Inhibition of STEP61 ameliorates deficits in mouse and hiPSC-based schizophrenia models.Genetically-Informed Patient Selection for iPSC Studies of Complex Diseases May Aid in Reducing Cellular Heterogeneity.Establishment of a novel three-dimensional primary culture model for hippocampal neurogenesis.Human iPSC neurons display activity-dependent neurotransmitter secretion: aberrant catecholamine levels in schizophrenia neurons.Moving stem cells to the clinic: potential and limitations for brain repair Adult Hippocampal Neurogenesis, Fear Generalization, and Stress.Evolving toward a human-cell based and multiscale approach to drug discovery for CNS disorders.A guide to generating and using hiPSC derived NPCs for the study of neurological diseases Advances in reprogramming-based study of neurologic disorders Probing disorders of the nervous system using reprogramming approaches.Reprogramming patient-derived cells to study the epilepsies Altered WNT Signaling in Human Induced Pluripotent Stem Cell Neural Progenitor Cells Derived from Four Schizophrenia Patients.Genomic DISC1 Disruption in hiPSCs Alters Wnt Signaling and Neural Cell Fate.Differential responses to lithium in hyperexcitable neurons from patients with bipolar disorder.Concise Review: Progress and Challenges in Using Human Stem Cells for Biological and Therapeutics Discovery: Neuropsychiatric Disorders.The proteome of schizophrenia.Dysregulation of miRNA-9 in a Subset of Schizophrenia Patient-Derived Neural Progenitor Cells Disease signatures for schizophrenia and bipolar disorder using patient-derived induced pluripotent stem cells.Increased abundance of translation machinery in stem cell-derived neural progenitor cells from four schizophrenia patients.Modeling psychiatric disorders: from genomic findings to cellular phenotypes L1-associated genomic regions are deleted in somatic cells of the healthy human brain.Current Opinion on the Role of Neurogenesis in the Therapeutic Strategies for Alzheimer Disease, Parkinson Disease, and Ischemic Stroke; Considering Neuronal Voiding Function.Molecular Mechanisms of Bipolar Disorder: Progress Made and Future Challenges.Stem and Progenitor Cell-Based Therapy of the Central Nervous System: Hopes, Hype, and Wishful Thinking.Analysis of induced pluripotent stem cells carrying 22q11.2 deletion.Human stem cell models of dementia.Human Inducible Pluripotent Stem Cells and Autism Spectrum Disorder: Emerging Technologies.Modeling psychiatric disorders with patient-derived iPSCs.Linking adult hippocampal neurogenesis with human physiology and disease.Altering the course of schizophrenia: progress and perspectives.Are reprogrammed cells a useful tool for studying dopamine dysfunction in psychotic disorders? A review of the current evidence.Engineering of Adult Neurogenesis and Gliogenesis.

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Modeling hippocampal neurogenesis using human pluripotent stem cells.

http://www.wikidata.org/entity/Q38460557

description

2014 nî lūn-bûn

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2014年论文

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name

Modeling hippocampal neurogenesis using human pluripotent stem cells.

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Modeling hippocampal neurogenesis using human pluripotent stem cells.

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Modeling hippocampal neurogenesis using human pluripotent stem cells.

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J.STEMCR.2014.01.009

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Stem Cell Reports

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Modeling hippocampal neurogenesis using human pluripotent stem cells.

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Arianna Mei

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David Lisuk

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Diana Xuan Yu

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Francesco Paolo Di Giorgio

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Fred H Gage

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Giovanna Silberman

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Jaeson Michael Grasmick

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Lauren McHenry

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Maria Carolina Marchetto

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Pedro Silberman

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P2860

Modelling schizophrenia using human induced pluripotent stem cells.

Dentate gyrus formation requires Emx2

NMDA-receptor-mediated, cell-specific integration of new neurons in adult dentate gyrus

Emx1 and Emx2 cooperate in initial phase of archipallium development

Loss of BETA2/NeuroD leads to malformation of the dentate gyrus and epilepsy

Prox1 is required for granule cell maturation and intermediate progenitor maintenance during brain neurogenesis

NeuroD is required for differentiation of the granule cells in the cerebellum and hippocampus

A local Wnt-3a signal is required for development of the mammalian hippocampus

Neuronal basic helix-loop-helix proteins (NEX and BETA2/Neuro D) regulate terminal granule cell differentiation in the hippocampus

An intrinsic mechanism of corticogenesis from embryonic stem cells

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295-310

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10.1016/J.STEMCR.2014.01.009

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3

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Kristen J. Brennand

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2014-02-27T00:00:00Z

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261141168

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