Marine antifungal theonellamides target 3beta-hydroxysterol to activate Rho1 signaling.
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Discovery that theonellasterol a marine sponge sterol is a highly selective FXR antagonist that protects against liver injury in cholestasisSusceptibility of outer hair cells to cholesterol chelator 2-hydroxypropyl-β-cyclodextrine is prestin-dependentVisualization of sterol-rich membrane domains with fluorescently-labeled theonellamidesMarine peptides and their anti-infective activitiesNoncanonical Function of a Small-Molecular Virulence Factor Coronatine against Plant Immunity: An In Vivo Raman Imaging Approach.Marine natural products: a new wave of drugs?Target identification of small molecules based on chemical biology approaches.Target identification for small bioactive molecules: finding the needle in the haystack.Distribution and functions of sterols and sphingolipids.Target deconvolution of bioactive small molecules: the heart of chemical biology and drug discovery.Biodistribution of arctigenin-loaded nanoparticles designed for multimodal imaging.Bicyclic Peptides as Next-Generation Therapeutics.Tetherin is an exosomal tether.The Lithistida: important sources of compounds useful in biomedical research.Marine pharmacology in 2009-2011: marine compounds with antibacterial, antidiabetic, antifungal, anti-inflammatory, antiprotozoal, antituberculosis, and antiviral activities; affecting the immune and nervous systems, and other miscellaneous mechanisBioactive Structure of Membrane Lipids and Natural Products Elucidated by a Chemistry-Based Approach.Natural products-prompted chemical biology: phenotypic screening and a new platform for target identification.Advances in identification and validation of protein targets of natural products without chemical modification.Vicenistatin induces early endosome-derived vacuole formation in mammalian cells.Integrated profiling methods for identifying the targets of bioactive compounds: MorphoBase and ChemProteoBase.Theonellamide G, a potent antifungal and cytotoxic bicyclic glycopeptide from the Red Sea marine sponge Theonella swinhoei.Emerging biopharmaceuticals from bioactive peptides derived from marine organisms.Heat shock proteins as key biological targets of the marine natural cyclopeptide perthamide C.Cholesterol impairment contributes to neuroserpin aggregation.Membrane permeabilizing action of amphidinol 3 and theonellamide A in raft-forming lipid mixtures.Microarray-based target identification using drug hypersensitive fission yeast expressing ORFeomeMarine metagenomics, a valuable tool for enzymes and bioactive compounds discovery
P2860
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P2860
Marine antifungal theonellamides target 3beta-hydroxysterol to activate Rho1 signaling.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Marine antifungal theonellamides target 3beta-hydroxysterol to activate Rho1 signaling.
@en
type
label
Marine antifungal theonellamides target 3beta-hydroxysterol to activate Rho1 signaling.
@en
prefLabel
Marine antifungal theonellamides target 3beta-hydroxysterol to activate Rho1 signaling.
@en
P2093
P2860
P50
P356
P1476
Marine antifungal theonellamides target 3beta-hydroxysterol to activate Rho1 signaling.
@en
P2093
Hisashi Kawasaki
Kunihiko Iwamoto
Miyuki Honda
Shigeki Matsunaga
Shinichi Nishimura
Toshihide Kobayashi
Yuko Arita
P2860
P2888
P304
P356
10.1038/NCHEMBIO.387
P577
2010-06-13T00:00:00Z