The opposing roles of the transcription factor E2A and its antagonist Id3 that orchestrate and enforce the naive fate of T cells.
about
Close link between development and function of gamma-delta T cellsThe establishment of B versus T cell identityHelix-loop-helix factor inhibitor of differentiation 3 regulates interleukin-5 expression and B-1a B cell proliferation.A functionally significant polymorphism in ID3 is associated with human coronary pathologyLoss of Id3 increases VCAM-1 expression, macrophage accumulation, and atherogenesis in Ldlr-/- miceId2 and Id3 maintain the regulatory T cell pool to suppress inflammatory diseaseLarge-scale quality analysis of published ChIP-seq data.Bcl11b and combinatorial resolution of cell fate in the T-cell gene regulatory network.Transcription factor achaete-scute homologue 2 initiates follicular T-helper-cell development.Aberrant production of IL-13 by T cells promotes exocrinopathy in Id3 knockout mice.Dynamic recruitment of Ets1 to both nucleosome-occupied and -depleted enhancer regions mediates a transcriptional program switch during early T-cell differentiation.T-cell TGF-β signaling abrogation restricts medulloblastoma progression.ID'ing innate and innate-like lymphoid cellsMaster regulators or lineage-specifying? Changing views on CD4+ T cell transcription factorsFli-1 overexpression in hematopoietic progenitors deregulates T cell development and induces pre-T cell lymphoblastic leukaemia/lymphoma.ICOS coreceptor signaling inactivates the transcription factor FOXO1 to promote Tfh cell differentiation.The E-Id protein axis modulates the activities of the PI3K-AKT-mTORC1-Hif1a and c-myc/p19Arf pathways to suppress innate variant TFH cell development, thymocyte expansion, and lymphomagenesis.T-cell receptor α enhancer is inactivated in αβ T lymphocytes.Biochemical and phosphoproteomic analysis of the helix-loop-helix protein E47.Core transcriptional regulatory circuit controlled by the TAL1 complex in human T cell acute lymphoblastic leukemia.Transcription factor networks directing the development, function, and evolution of innate lymphoid effectorsCutting edge: Ly9 (CD229), a SLAM family receptor, negatively regulates the development of thymic innate memory-like CD8+ T and invariant NKT cells.E2A transcription factors limit expression of Gata3 to facilitate T lymphocyte lineage commitment.Satb1 regulates the self-renewal of hematopoietic stem cells by promoting quiescence and repressing differentiation commitment.Dynamic changes in Id3 and E-protein activity orchestrate germinal center and plasma cell development.Id2 reinforces TH1 differentiation and inhibits E2A to repress TFH differentiation.The transcription factor Twist1 limits T helper 17 and T follicular helper cell development by repressing the gene encoding the interleukin-6 receptor α chain.Combined deletion of Id2 and Id3 genes reveals multiple roles for E proteins in invariant NKT cell development and expansionThe transcriptional regulators Id2 and Id3 control the formation of distinct memory CD8+ T cell subsets.E2A predicts prognosis of colorectal cancer patients and regulates cancer cell growth by targeting miR-320aDendritic cell fate is determined by BCL11A.Remembering one's ID/E-ntity: E/ID protein regulation of T cell memory.Transcriptional control of early T and B cell developmental choicesDevelopmental gene networks: a triathlon on the course to T cell identity.T follicular helper cell differentiation, function, and roles in disease.Forging T-Lymphocyte Identity: Intersecting Networks of Transcriptional Control.Epigenetic landscapes reveal transcription factors that regulate CD8+ T cell differentiation.Tcra enhancer activation by inducible transcription factors downstream of pre-TCR signaling.Bcl6 expressing follicular helper CD4 T cells are fate committed early and have the capacity to form memory.Follicular CXCR5- expressing CD8(+) T cells curtail chronic viral infection.
P2860
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P2860
The opposing roles of the transcription factor E2A and its antagonist Id3 that orchestrate and enforce the naive fate of T cells.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
The opposing roles of the tran ...... rce the naive fate of T cells.
@en
type
label
The opposing roles of the tran ...... rce the naive fate of T cells.
@en
prefLabel
The opposing roles of the tran ...... rce the naive fate of T cells.
@en
P2093
P2860
P356
P1433
P1476
The opposing roles of the tran ...... orce the naive fate of T cells
@en
P2093
Cornelis Murre
Kazuko Miyazaki
Masaki Miyazaki
Richard R Rivera
Yasutoshi Agata
P2860
P304
P356
10.1038/NI.2086
P407
P50
P577
2011-08-21T00:00:00Z