Master regulators or lineage-specifying? Changing views on CD4+ T cell transcription factors
about
The IL-23-IL-17 immune axis: from mechanisms to therapeutic testingCellular and molecular players in adipose tissue inflammation in the development of obesity-induced insulin resistanceHistone-fold domain protein NF-Y promotes chromatin accessibility for cell type-specific master transcription factors.In vivo RNA interference screens identify regulators of antiviral CD4(+) and CD8(+) T cell differentiation.Complex interactions of transcription factors in mediating cytokine biology in T cells.Regulatory T cells and immune tolerance in the intestine.Transiently reduced PI3K/Akt activity drives the development of regulatory function in antigen-stimulated Naïve T-cells.Stable T-bet(+)GATA-3(+) Th1/Th2 hybrid cells arise in vivo, can develop directly from naive precursors, and limit immunopathologic inflammation.Linking T-cell receptor sequence to functional phenotype at the single-cell level.TCR-Signaling Events in Cellular Metabolism and Specialization.Transcriptional regulation of T cell metabolism.HIV Skews the Lineage-Defining Transcriptional Profile of Mycobacterium tuberculosis-Specific CD4+ T Cells.In vivo RNAi screens: concepts and applications.IL-12 induced the generation of IL-21- and IFN-γ-co-expressing poly-functional CD4+ T cells from human naive CD4+ T cells.Mixed lineage leukemia 5 (MLL5) protein regulates cell cycle progression and E2F1-responsive gene expression via association with host cell factor-1 (HCF-1)The microRNA cluster miR-17∼92 promotes TFH cell differentiation and represses subset-inappropriate gene expression.Antagonism of histamine H4 receptors exacerbates clinical and pathological signs of experimental autoimmune encephalomyelitis.Conditions for the generation of cytotoxic CD4(+) Th cells that enhance CD8(+) CTL-mediated tumor regression.Th9 cell development requires a BATF-regulated transcriptional networkFrom a gene-centric to whole-proteome view of differentiation of T helper cell subsets.Genome-wide regulatory analysis reveals that T-bet controls Th17 lineage differentiation through direct suppression of IRF4.TGFβ receptor mutations impose a strong predisposition for human allergic diseaseThe transcription factors T-bet and Runx are required for the ontogeny of pathogenic interferon-γ-producing T helper 17 cells.Type I IFN induces binding of STAT1 to Bcl6: divergent roles of STAT family transcription factors in the T follicular helper cell genetic programFighting Viral Infections and Virus-Driven Tumors with Cytotoxic CD4+ T Cells.Transcription factor interplay in T helper cell differentiation.Regulatory mechanisms that control T-follicular helper and T-helper 1 cell flexibility.The chromatin landscape and transcription factors in T cell programming.CD4 T-cell memory generation and maintenanceYin-Yang Regulation of RORγt Protein Complex in Th17 Differentiation.Forging T-Lymphocyte Identity: Intersecting Networks of Transcriptional Control.From neutrophils to macrophages: differences in regional adipose tissue depots.Cannabinoids decrease the th17 inflammatory autoimmune phenotype.Quantitative Proteomics of Gut-Derived Th1 and Th1/Th17 Clones Reveal the Presence of CD28+ NKG2D- Th1 Cytotoxic CD4+ T cellsIL-4 enhances IL-10 production in Th1 cells: implications for Th1 and Th2 regulation.Neonatal and adult recent thymic emigrants produce IL-8 and express complement receptors CR1 and CR2.Th9 Cells: New Member of T Helper Cell Family.Trans-presentation of IL-15 modulates STAT5 activation and Bcl-6 expression in TH1 cells.The transcription factor musculin promotes the unidirectional development of peripheral Treg cells by suppressing the TH2 transcriptional programInsufficient interleukin-12 signalling favours differentiation of human CD4(+) and CD8(+) T cells into GATA-3(+) and GATA-3(+) T-bet(+) subsets in humanized mice.
P2860
Q27687800-9A9D6E6E-E6A7-45F6-9A43-84DDC98A4207Q30009848-17618531-8FDC-4A6D-9B0D-543739274D8EQ34149107-AB2C4114-EDE2-488F-A69F-0DEE70F93F16Q34160642-4A334B9F-2F8B-49C7-B1D1-A5CEC72F1E4FQ34240220-FD3E71E3-A8B4-413B-BFBC-1C0831528643Q34789108-C2C43EDD-B19F-4427-9FF0-2ADDB7CEE7E8Q34848279-6EA9DC6B-D243-47DA-9C83-232DD5EE9757Q34970100-A1EA6EC7-4942-474A-BC2F-5C829B241701Q35111823-4A69980D-35B3-425D-BE85-0254E3E67B3BQ35693169-0CA73040-D60C-4ED2-8B69-1926980DFCF6Q36372801-C6E644E7-0749-4A9A-867A-9CFB23C0E551Q36706314-C24C95B6-4A32-4F90-8863-7958A0C6C281Q36736715-A5A32CEF-CED1-4E1A-9719-FE1A9DBDB4ABQ36780627-626BEB36-6391-4B22-AFF6-2B9A6EB68F6BQ36929031-101FD30E-CF4F-4D64-B84D-93F7443B4EBAQ37038839-96BF9446-D1CF-45AA-B73D-9CAE56F3FACEQ37151149-60E7E5DF-6535-4203-89A5-09100121E26FQ37223717-811346FD-F014-4D30-ADCC-899680D05F75Q37259259-FE94B6B8-7FA3-4077-A354-F10BE3CEE56BQ37336620-846C4860-C3C5-47AC-8F6A-21AFBB12F4A6Q37380878-BEAE8CB5-868C-4B08-A499-D2E6FF35E060Q37526777-B2795A5B-4508-4F8B-AE0B-C8C84AF85A50Q37662658-B3546447-AC00-4CFD-BE11-87EA767BCE11Q37666675-14F49454-23F2-44F7-B816-4074C697AFF1Q37667998-18031CBF-876A-4F73-A4D1-820BE762CD01Q38123463-E5021E45-19A6-4F25-88AC-06E705DD507CQ38147883-8FB9C0D4-752C-4CBB-A266-A34A9506B0B7Q38202333-3E892E1D-97C1-434B-81F4-A334C086DA8BQ38221173-72D15B4D-BBFB-4961-8579-A10C1C8D9F15Q38262156-C4534BB7-F8D4-4846-8465-E850881B2071Q38320682-64244FC2-9C27-4DF1-B0A1-AF46A75185BFQ38669187-69B81054-E9C2-48BE-B704-C49B0B8884FDQ39119286-8AD0C519-B9F1-4798-8C93-5A901D18BB36Q39682036-9C737949-5419-4856-A089-71F6AEF774C8Q40044539-0B057019-C4D4-4ACA-AC4C-ECE679041E91Q40080795-F4016913-9397-470A-BF50-EFBCDBCAE9BEQ40224209-FD702E23-E52C-4D24-869D-1690A2DD75E1Q40937846-329EC2DF-BB01-4E64-824A-C6BE8AE8187DQ41470945-D2864A57-631F-4760-82EF-44EF242B6E3DQ42217868-3EAD6895-29B0-4E6A-A292-9BA788C41F20
P2860
Master regulators or lineage-specifying? Changing views on CD4+ T cell transcription factors
description
2012 nî lūn-bûn
@nan
2012 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Master regulators or lineage-s ...... + T cell transcription factors
@ast
Master regulators or lineage-s ...... + T cell transcription factors
@en
Master regulators or lineage-s ...... + T cell transcription factors
@nl
type
label
Master regulators or lineage-s ...... + T cell transcription factors
@ast
Master regulators or lineage-s ...... + T cell transcription factors
@en
Master regulators or lineage-s ...... + T cell transcription factors
@nl
prefLabel
Master regulators or lineage-s ...... + T cell transcription factors
@ast
Master regulators or lineage-s ...... + T cell transcription factors
@en
Master regulators or lineage-s ...... + T cell transcription factors
@nl
P2860
P356
P1476
Master regulators or lineage-s ...... + T cell transcription factors
@en
P2093
Amy S Weinmann
Kenneth J Oestreich
P2860
P2888
P304
P356
10.1038/NRI3321
P577
2012-10-12T00:00:00Z
P6179
1034588801