about
Pyrrolobenzodiazepines (PBDs) do not bind to DNA G-quadruplexesCovalent Bonding of Pyrrolobenzodiazepines (PBDs) to Terminal Guanine Residues within Duplex and Hairpin DNA FragmentsObservation of a dynamic equilibrium between DNA hairpin and duplex forms of covalent adducts of a minor groove binding agent.Effect of microwave irradiation on covalent ligand-DNA interactions.Current Advances in Developing Inhibitors of Bacterial Multidrug Efflux PumpsA novel small-molecule inhibitor of IL-6 signalling.Observation of a single-stranded DNA/pyrrolobenzodiazepine adduct.From Anthramycin to Pyrrolobenzodiazepine (PBD)-Containing Antibody-Drug Conjugates (ADCs).Effect of hairpin loop structure on reactivity, sequence preference and adduct orientation of a DNA-interactive pyrrolo[2,1-c][1,4]benzodiazepine (PBD) antitumour agent.The minor groove-binding agent ELB-21 forms multiple interstrand and intrastrand covalent cross-links with duplex DNA and displays potent bactericidal activity against methicillin-resistant Staphylococcus aureus.DNA Sequence Preference and Adduct Orientation of Pyrrolo[2,1-c][1,4]benzodiazepine Antitumor AgentsThe pyrrolobenzodiazepine dimer SJG-136 forms sequence-dependent intrastrand DNA cross-links and monoalkylated adducts in addition to interstrand cross-links.Topical therapies for skin cancer and actinic keratosis.Novel pyridyl nitrofuranyl isoxazolines show antibacterial activity against multiple drug resistant Staphylococcus species.An overview of bacterial efflux pumps and computational approaches to study efflux pump inhibitors.The use of molecular dynamics simulations to evaluate the DNA sequence-selectivity of G-A cross-linking PBD-duocarmycin dimers.Recent advances in targeting the telomeric G-quadruplex DNA sequence with small molecules as a strategy for anticancer therapies.Topical delivery of anthramycin I. Influence of neat solvents.Novel 1-(2-aryl-2-adamantyl)piperazine derivatives with antiproliferative activity.Cytotoxic Naphthoquinone and Azaanthraquinone Derivatives from an Endophytic Fusarium solani.GC-targeted C8-linked pyrrolobenzodiazepine-biaryl conjugates with femtomolar in vitro cytotoxicity and in vivo antitumor activity in mouse models.The prenylated dioxopiperazine alkaloid Cristatin A has selective telomeric DNA G-quadruplex stabilising properties.Biaryl polyamides as a new class of DNA quadruplex-binding ligands.Triaryl Benzimidazoles as a New Class of Antibacterial Agents against Resistant Pathogenic Microorganisms.Effect of base sequence on the DNA cross-linking properties of pyrrolobenzodiazepine (PBD) dimers.Antistaphylococcal activity of DNA-interactive pyrrolobenzodiazepine (PBD) dimers and PBD-biaryl conjugates.Fluoxetine and thioridazine inhibit efflux and attenuate crystalline biofilm formation by Proteus mirabilis.Cytotoxicity and antibacterial activity of extractives from Wedelia calendulacea.Computational studies support the role of the C7-sibirosamine sugar of the pyrrolobenzodiazepine (PBD) sibiromycin in transcription factor inhibition.In Silico and in Vitro Screening for P-Glycoprotein Interaction with Tenofovir, Darunavir, and Dapivirine: An Antiretroviral Drug Combination for Topical Prevention of Colorectal HIV Transmission.C8-Linked Pyrrolobenzodiazepine Monomers with Inverted Building Blocks Show Selective Activity against Multidrug Resistant Gram-Positive Bacteria.Crispenes F and G, cis-Clerodane Furanoditerpenoids from Tinospora crispa, Inhibit STAT3 Dimerization.Sequence-selective binding of C8-conjugated pyrrolobenzodiazepines (PBDs) to DNA.Investigation of the protein alkylation sites of the STAT3:STAT3 inhibitor Stattic by mass spectrometry.Role of bacterial efflux pumps in biofilm formation.Methylene-linked bis-phenylbenzimidazoles - a new scaffold to target telomeric DNA/RNA hybrid duplex.Antimicrobial molecules in the lung: formulation challenges and future directions for innovation.Preliminary Cytotoxicity Screening of Some Medicinal Plants of BangladeshStereochenols A and B, two quinones from Stereospermum chelonoidesFusaproliferin, a Fungal Mycotoxin, Shows Cytotoxicity against Pancreatic Cancer Cell Lines
P50
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P50
description
hulumtues
@sq
researcher
@en
scheikundige
@nl
հետազոտող
@hy
name
Khondaker M. Rahman
@en
Khondaker M. Rahman
@es
Khondaker M. Rahman
@sl
Khondaker Miraz Rahman
@de
type
label
Khondaker M. Rahman
@en
Khondaker M. Rahman
@es
Khondaker M. Rahman
@sl
Khondaker Miraz Rahman
@de
altLabel
Miraz
@en
prefLabel
Khondaker M. Rahman
@en
Khondaker M. Rahman
@es
Khondaker M. Rahman
@sl
Khondaker Miraz Rahman
@de
P227
P1053
M-2749-2017
P1153
56232895400
P21
P214
561154983524767860008
P227
1177094258
P31
P3829
P496
0000-0001-8566-8648
P569
2000-01-01T00:00:00Z
P734
P7859
lccn-n2018190186