The metabolic effects of GDF15 are mediated by the orphan receptor GFRAL.
about
Ret receptor tyrosine kinase sustains proliferation and tissue maturation in intestinal epithelia.TGF-β contamination of purified recombinant GDF15.Growth differentiation factor 15 mediates epithelial mesenchymal transition and invasion of breast cancers through IGF-1R-FoxM1 signaling.BMPs as new insulin sensitizers: enhanced glucose uptake in mature 3T3-L1 adipocytes via PPARγ and GLUT4 upregulation.Exercise increases circulating GDF15 in humans.Silver linings on the horizon: highlights from the 10th Cachexia Conference.GDF15 and energy balance: homing in on a mechanism.Structure and biophysical characterisation of the human full-length Neurturin-GFRa2 complex - a role for heparan sulfate in signalling.Fasting exacerbates hepatic growth differentiation factor 15 to promote fatty acid β-oxidation and ketogenesis via activating XBP1 signaling in liver.GDF15 promotes the proliferation of cervical cancer cells by phosphorylating AKT1 and Erk1/2 through the receptor ErbB2.Control of (pre)-analytical aspects in immunoassay measurements of metabolic hormones in rodents.The Global Epidemic of the Metabolic Syndrome.New extracellular factors in glioblastoma multiforme development: neurotensin, growth differentiation factor-15, sphingosine-1-phosphate and cytomegalovirus infection.Reduced oxidative capacity in macrophages results in systemic insulin resistance.Moonlighting Activity of Secreted Inflammation-Regulatory Proteins.Binding of EphrinA5 to RET receptor tyrosine kinase: An in vitro study.Preclinical evaluation of a GFRA1 targeted antibody-drug conjugate in breast cancer.CRP Stimulates GDF15 Expression in Endothelial Cells through p53.Presence of growth/differentiation factor-15 cytokine in human follicular fluid, granulosa cells, and oocytesRet and Substrate-Derived TGF-β Maverick Regulate Space-Filling Dendrite Growth in Drosophila Sensory NeuronsPathogenesis of Nonalcoholic Steatohepatitis and Hormone-Based Therapeutic ApproachesGDF15 deficiency promotes high fat diet-induced obesity in mice
P2860
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P248
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P2860
The metabolic effects of GDF15 are mediated by the orphan receptor GFRAL.
description
2017 nî lūn-bûn
@nan
2017年の論文
@ja
2017年論文
@yue
2017年論文
@zh-hant
2017年論文
@zh-hk
2017年論文
@zh-mo
2017年論文
@zh-tw
2017年论文
@wuu
2017年论文
@zh
2017年论文
@zh-cn
name
The metabolic effects of GDF15 are mediated by the orphan receptor GFRAL.
@en
type
label
The metabolic effects of GDF15 are mediated by the orphan receptor GFRAL.
@en
prefLabel
The metabolic effects of GDF15 are mediated by the orphan receptor GFRAL.
@en
P2093
P2860
P921
P356
P1433
P1476
The metabolic effects of GDF15 are mediated by the orphan receptor GFRAL.
@en
P2093
Avinash Muppidi
Bei B Zhang
Dana K Sindelar
Gavin C Barnard
Jason X Tang
John H Sloan
Jorge Alsina-Fernandez
Kimberly K Ballman
P2860
P2888
P356
10.1038/NM.4393
P407
P577
2017-08-28T00:00:00Z