Connexin channels provide a target to manipulate brain endothelial calcium dynamics and blood-brain barrier permeability.
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Role of Astroglial Hemichannels and Pannexons in Memory and Neurodegenerative DiseasesIntracellular Cleavage of the Cx43 C-Terminal Domain by Matrix-Metalloproteases: A Novel Contributor to Inflammation?Connexins and Pannexins: New Insights into Microglial Functions and DysfunctionsPannexin channel and connexin hemichannel expression in vascular function and inflammationConnexin 43 hemichannels contribute to cytoplasmic Ca2+ oscillations by providing a bimodal Ca2+-dependent Ca2+ entry pathway.Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraineNeuron-Glia Crosstalk in the Autonomic Nervous System and Its Possible Role in the Progression of Metabolic Syndrome: A New HypothesisTransient receptor potential channels and regulation of lung endothelial permeability.Connexin and pannexin signaling pathways, an architectural blueprint for CNS physiology and pathology?Ca²⁺-dependent nitric oxide release in the injured endothelium of excised rat aorta: a promising mechanism applying in vascular prosthetic devices in aging patients.Intercellular Ca(2+) waves: mechanisms and function.Connexin 43 is an emerging therapeutic target in ischemia/reperfusion injury, cardioprotection and neuroprotectionGap junctions and hemichannels: communicating cell death in neurodevelopment and diseaseConnexin mimetic peptides inhibit Cx43 hemichannel opening triggered by voltage and intracellular Ca2+ elevationConnexin and pannexin hemichannels in brain glial cells: properties, pharmacology, and roles.Neurological manifestations of oculodentodigital dysplasia: a Cx43 channelopathy of the central nervous system?High bone mass in mice lacking Cx37 because of defective osteoclast differentiation.Paracrine signaling through plasma membrane hemichannelsManipulating connexin communication channels: use of peptidomimetics and the translational outputs.Functional role of connexins and pannexins in the interaction between vascular and nervous system.Connexin hemichannel induced vascular leak suggests a new paradigm for cancer therapy.Hunting for connexin hemichannels.A new angle on blood-CNS interfaces: a role for connexins?Control of the neurovascular coupling by nitric oxide-dependent regulation of astrocytic Ca(2+) signaling.Transcriptome profiling of brain edemas caused by influenza infection and lipopolysaccharide treatment.Into rather unexplored terrain-transcellular transport across the blood-brain barrier.Connexins and their channels in inflammation.Physiological Functions of Glial Cell Hemichannels.Connexin channel and its role in diabetic retinopathy.Connexin Channels at the Glio-Vascular Interface: Gatekeepers of the Brain.Inhibitors of connexin and pannexin channels as potential therapeutics.Blood-brain barrier breakdown involves four distinct stages of vascular damage in various models of experimental focal cerebral ischemia.Selective inhibition of Cx43 hemichannels by Gap19 and its impact on myocardial ischemia/reperfusion injury.The Microvascular Gap Junction Channel: A Route to Deliver MicroRNAs for Neurological Disease TreatmentInhibition of connexin hemichannels alleviates non-alcoholic steatohepatitis in mice.Blocking connexin channels improves embryo development of vitrified bovine blastocysts.Stroke-induced blood-brain barrier breakdown along the vascular tree - No preferential affection of arteries in different animal models and in humans.Connexin 43 gap junctions contribute to brain endothelial barrier hyperpermeability in familial cerebral cavernous malformations type III by modulating tight junction structure.Connexins in Cardiovascular and Neurovascular Health and Disease: Pharmacological Implications.Tonabersat Prevents Inflammatory Damage in the Central Nervous System by Blocking Connexin43 Hemichannels.
P2860
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P2860
Connexin channels provide a target to manipulate brain endothelial calcium dynamics and blood-brain barrier permeability.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
@zh
2011年學術文章
@zh-hant
name
Connexin channels provide a ta ...... od-brain barrier permeability.
@en
type
label
Connexin channels provide a ta ...... od-brain barrier permeability.
@en
prefLabel
Connexin channels provide a ta ...... od-brain barrier permeability.
@en
P2093
P2860
P50
P356
P1476
Connexin channels provide a ta ...... od-brain barrier permeability.
@en
P2093
Alexander M Simon
Anaelle da Costa
Elke De Vuyst
Elke Decrock
Gaspard De Ley
Geneviève Dupont
Marijke De Bock
Maxime Culot
Mélissa Bol
P2860
P304
P356
10.1038/JCBFM.2011.86
P577
2011-06-08T00:00:00Z