Reverse translation of adverse event reports paves the way for de-risking preclinical off-targets.

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The benefits of data mining.Population scale retrospective analysis reveals distinctive antidepressant and anxiolytic effects of diclofenac, ketoprofen and naproxen in patients with pain.

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Reverse translation of adverse event reports paves the way for de-risking preclinical off-targets.

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Pierre Farmer

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Steven Whitebread

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William DuMouchel

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P2860

Nonsteroidal Anti-inflammatory Drugs and Cyclooxygenase-2 Inhibitors for Primary Prevention of Colorectal Cancer: A Systematic Review Prepared for the U.S. Preventive Services Task Force

Effect of Rosiglitazone on the Risk of Myocardial Infarction and Death from Cardiovascular Causes

DrugBank 4.0: shedding new light on drug metabolism

Data-driven prediction of drug effects and interactions

Statistical aspects of the analysis of data from retrospective studies of disease

Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis. VIGOR Study Group

Evidence for possible involvement of 5-HT(2B) receptors in the cardiac valvulopathy associated with fenfluramine and other serotonergic medications

Timing of new black box warnings and withdrawals for prescription medications

Analysis of pharmacology data and the prediction of adverse drug reactions and off-target effects from chemical structure

Hepatosplenic T cell lymphoma associated with infliximab use in young patients treated for inflammatory bowel disease

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scholarly article

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10.7554/ELIFE.25818

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Eugen Lounkine

Mateusz Maciejewski

Laszlo Urban

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2017-08-08T00:00:00Z

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28786378

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Reverse translation of adverse event reports paves the way for de-risking preclinical off-targets.

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P2860

P2860

Reverse translation of adverse event reports paves the way for de-risking preclinical off-targets.

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