Discovery of small molecule inhibitors for the C. elegans caspase CED-3 by high-throughput screening.

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Discovery of small molecule inhibitors for the C. elegans caspase CED-3 by high-throughput screening.

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2017 nî lūn-bûn

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2017年学术文章

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Discovery of small molecule in ...... by high-throughput screening.

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Discovery of small molecule in ...... by high-throughput screening.

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Discovery of small molecule in ...... by high-throughput screening.

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P1476

Discovery of small molecule in ...... by high-throughput screening.

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P2093

David R Lamson

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Ginger R Smith

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Rihe Liu

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Scott J Brantley

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Steven W Cotten

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P2860

Advancing Biological Understanding and Therapeutics Discovery with Small-Molecule Probes

Caspase dependent programmed cell death in developing embryos: a potential target for therapeutic intervention against pathogenic nematodes

The core apoptotic executioner proteins CED-3 and CED-4 promote initiation of neuronal regeneration in Caenorhabditis elegans

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

Mammalian caspases: structure, activation, substrates, and functions during apoptosis

A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme

A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis

Molecular mechanisms of caspase regulation during apoptosis

Homogeneous, bioluminescent protease assays: caspase-3 as a model.

P304

773-779

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scholarly article

P356

10.1016/J.BBRC.2017.07.100

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English

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P478

491

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K P Williams

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2017-07-18T00:00:00Z

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P698

28733033

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P921

Caenorhabditis elegans

P932

5590106

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