BCR: a new target in resistance mediated by BCR/ABL-315I? - Wikidata - wikimedia - TriplyDB

BCR: a new target in resistance mediated by BCR/ABL-315I?

BCR: a new target in resistance mediated by BCR/ABL-315I?

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BCR: a new target in resistance mediated by BCR/ABL-315I?

http://www.wikidata.org/entity/Q38710583

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2016 nî lūn-bûn

@nan

2016年の論文

@ja

2016年学术文章

@wuu

2016年学术文章

@zh-cn

2016年学术文章

@zh-hans

2016年学术文章

@zh-my

2016年学术文章

@zh-sg

2016年學術文章

@yue

2016年學術文章

@zh

2016年學術文章

@zh-hant

name

BCR: a new target in resistance mediated by BCR/ABL-315I?

@en

type

label

BCR: a new target in resistance mediated by BCR/ABL-315I?

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BCR: a new target in resistance mediated by BCR/ABL-315I?

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GENESANDCANCER.93

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BCR: a new target in resistance mediated by BCR/ABL-315I?

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Anahita Rafiei

http://www.w3.org/2001/XMLSchema#string

Claudia Oancea

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Gerhart Oliver Ottmann

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Isabella Haberbosch

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P2860

Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling

Bcr-Abl oncoproteins bind directly to activators of the Ras signalling pathway

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

AP24534, a pan-BCR-ABL inhibitor for chronic myeloid leukemia, potently inhibits the T315I mutant and overcomes mutation-based resistance

Sequential ABL kinase inhibitor therapy selects for compound drug-resistant BCR-ABL mutations with altered oncogenic potency

Structural mechanism for STI-571 inhibition of abelson tyrosine kinase

Ponatinib in refractory Philadelphia chromosome-positive leukemias.

The structure of Dasatinib (BMS-354825) bound to activated ABL kinase domain elucidates its inhibitory activity against imatinib-resistant ABL mutants

BCR-ABL-induced oncogenesis is mediated by direct interaction with the SH2 domain of the GRB-2 adaptor protein.

Allosteric inhibitors of Bcr-abl-dependent cell proliferation.

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36-46

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scholarly article

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10.18632/GENESANDCANCER.93

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1-2

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7

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2016-01-01T00:00:00Z

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27014420

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4773704

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