A large fraction of HLA class I ligands are proteasome-generated spliced peptides.
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Dual non-contiguous peptide occupancy of HLA class I evoke antiviral human CD8 T cell response and form neo-epitopes with self-antigens.Extracellular proteasome-osteopontin circuit regulates cell migration with implications in multiple sclerosis.Tools to define the melanoma-associated immunopeptidome.I've got algorithm: predicting tumor and autoimmune peptide targets for CD8+ T cells.HIV-1 adaptation to NK cell-mediated immune pressure.Next-Generation Sequencing to Guide Treatment of Advanced Melanoma.Immune targets and neoantigens for cancer immunotherapy and precision medicine.Neoepitopes as cancer immunotherapy targets: key challenges and opportunities.Adaptive Immunity Is the Key to the Understanding of Autoimmune and Paraneoplastic Inflammatory Central Nervous System Disorders.Introduction: MHC/KIR and governance of specificity.A novel polyepitope vaccine elicited HIV peptide specific CD4+ T cell responses in HLA-A2/DRB1 transgenic mice.Immunobiography and the Heterogeneity of Immune Responses in the Elderly: A Focus on Inflammaging and Trained Immunity.Mass spectrometry-based proteomic exploration of the human immune system: focus on the inflammasome, global protein secretion, and T cells.A strongly selected mutation in the HIV-1 genome is independent of T cell responses and neutralizing antibodies.The SysteMHC Atlas project.Novel insights into the HLA class I immunopeptidome and T-cell immunosurveillance.Unbiased Identification of T-Cell Receptors Targeting Immunodominant Peptide-MHC Complexes for T-Cell Receptor Immunotherapy.Immunity to CRISPR Cas9 and Cas12a therapeutics.C-terminal modification of the insulin B:11-23 peptide creates superagonists in mouse and human type 1 diabetes.HLA Class I or Class II and Disease Association: Catch the Difference If You Can.The Role of Electron Transfer Dissociation in Modern Proteomics.Identification and Characterization of Neoantigens As Well As Respective Immune Responses in Cancer Patients.An Unexpected Major Role for Proteasome-Catalyzed Peptide Splicing in Generation of T Cell Epitopes: Is There Relevance for Vaccine Development?The role of mass spectrometry and proteogenomics in the advancement of HLA epitope prediction.Antigen Identification for Orphan T Cell Receptors Expressed on Tumor-Infiltrating Lymphocytes.Lysine-Less Variants of Spinal Muscular Atrophy SMN and SMNΔ7 Proteins Are Degraded by the Proteasome Pathway.Informatics for cancer immunotherapy.Targeting Intracellular Antigens with pMHC-Binding Antibodies: A Phage Display Approach.Peptide splicing by the proteasome.Novel Identified HLA-A*0201-Restricted Hantaan Virus Glycoprotein Cytotoxic T-Cell Epitopes Could Effectively Induce Protective Responses in HLA-A2.1/Kb Transgenic Mice May Associate with the Severity of Hemorrhagic Fever with Renal Syndrome.Shuffling peptides to create T-cell epitopes: does the immune system play cards?HLA variation and disease.Discrimination Between Human Leukocyte Antigen Class I-Bound and Co-Purified HIV-Derived Peptides in Immunopeptidomics Workflows.CD8 + T-cell responses in vaccination: reconsidering targets and function in the context of chronic antigen stimulation.Immunological-based approaches for cancer therapyA tissue-based draft map of the murine MHC class I immunopeptidomeMapping the tumour human leukocyte antigen (HLA) ligandome by mass spectrometryDetermining T-cell specificity to understand and treat diseaseIdentification of Nucleophilic Probes for Protease-Mediated TranspeptidationBiological consequences of structural and functional proteasome diversity
P2860
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P2860
A large fraction of HLA class I ligands are proteasome-generated spliced peptides.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
A large fraction of HLA class I ligands are proteasome-generated spliced peptides.
@en
type
label
A large fraction of HLA class I ligands are proteasome-generated spliced peptides.
@en
prefLabel
A large fraction of HLA class I ligands are proteasome-generated spliced peptides.
@en
P2093
P2860
P50
P356
P1433
P1476
A large fraction of HLA class I ligands are proteasome-generated spliced peptides
@en
P2093
Alessandro Sette
Anita Jeko
Daniel E Bunting
Fabio Marino
John Sidney
Michael P H Stumpf
Peter M Kloetzel
P2860
P304
P356
10.1126/SCIENCE.AAF4384
P407
P577
2016-10-20T00:00:00Z