Antigen processing influences HIV-specific cytotoxic T lymphocyte immunodominance - Wikidata - wikimedia - TriplyDB

Antigen processing influences HIV-specific cytotoxic T lymphocyte immunodominance

Antigen processing influences HIV-specific cytotoxic T lymphocyte immunodominance

http://www.wikidata.org/entity/Q27655357

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Identification of minimal human MHC-restricted CD8+ T-cell epitopes within the Plasmodium falciparum circumsporozoite protein (CSP)A peptide filtering relation quantifies MHC class I peptide optimization Challenges and Opportunities for T-Cell-Mediated Strategies to Eliminate HIV Reservoirs Mechanisms of HIV protein degradation into epitopes: implications for vaccine design Antigenic peptide trimming by ER aminopeptidases--insights from structural studies High avidity CD8+ T cells efficiently eliminate motile HIV-infected targets and execute a locally focused program of anti-viral function Constraints within major histocompatibility complex class I restricted peptides: Presentation and consequences for T-cell recognition Rationally designed inhibitor targeting antigen-trimming aminopeptidases enhances antigen presentation and cytotoxic T-cell responses Large scale analysis of phenotype-pathway relationships based on GWAS results A vaccine encoding conserved promiscuous HIV CD4 epitopes induces broad T cell responses in mice transgenic to multiple common HLA class II molecules Newcastle disease virus-vectored vaccines expressing the hemagglutinin or neuraminidase protein of H5N1 highly pathogenic avian influenza virus protect against virus challenge in monkeys.CTL escape mediated by proteasomal destruction of an HIV-1 cryptic epitope Generation of robust CD8+ T-cell responses against subdominant epitopes in conserved regions of HIV-1 by repertoire mining with mimotopes.Design of immunogenic and effective multi-epitope DNA vaccines for melanoma.Protease cleavage sites in HIV-1 gp120 recognized by antigen processing enzymes are conserved and located at receptor binding sites Balancing selection maintains a form of ERAP2 that undergoes nonsense-mediated decay and affects antigen presentation.Maintenance or emergence of chronic phase secondary cytotoxic T lymphocyte responses after loss of acute phase immunodominant responses does not protect SIV-infected rhesus macaques from disease progression.The antiviral efficacy of HIV-specific CD8⁺ T-cells to a conserved epitope is heavily dependent on the infecting HIV-1 isolate.Protective efficacy of serially up-ranked subdominant CD8+ T cell epitopes against virus challenges Subdominant/cryptic CD8 T cell epitopes contribute to resistance against experimental infection with a human protozoan parasite.Unique CRF01_AE Gag CTL epitopes associated with lower HIV-viral load and delayed disease progression in a cohort of HIV-infected Thais.POPISK: T-cell reactivity prediction using support vector machines and string kernels.The effect of HLA polymorphisms on the recognition of Gag epitopes in HIV-1 CRF01_AE infection.Development of a novel in silico docking simulation model for the fine HIV-1 cytotoxic T lymphocyte epitope mapping.Autologous HIV-1 clade-B Nef peptides elicit increased frequency, breadth and function of CD8+ T-cells compared to consensus peptides.Rapid antigen processing and presentation of a protective and immunodominant HLA-B*27-restricted hepatitis C virus-specific CD8+ T-cell epitope.A novel protective MHC-I haplotype not associated with dominant Gag-specific CD8+ T-cell responses in SIVmac239 infection of Burmese rhesus macaques.T Cell receptor clonotype influences epitope hierarchy in the CD8+ T cell response to respiratory syncytial virus infection.The immune response during acute HIV-1 infection: clues for vaccine development.The T-cell response to HIV.Location of the CD8 T cell epitope within the antigenic precursor determines immunogenicity and protection against the Toxoplasma gondii parasite.Properties of MHC class I presented peptides that enhance immunogenicity Alphavirus replicon DNA expressing HIV antigens is an excellent prime for boosting with recombinant modified vaccinia Ankara (MVA) or with HIV gp140 protein antigen.Comparison of immune responses generated by optimized DNA vaccination against SIV antigens in mice and macaques Broad HIV epitope specificity and viral inhibition induced by multigenic HIV-1 adenovirus subtype 35 vector vaccine in healthy uninfected adults High-functional-avidity cytotoxic T lymphocyte responses to HLA-B-restricted Gag-derived epitopes associated with relative HIV control Vaccine-induced HIV-specific CD8+ T cells utilize preferential HLA alleles and target-specific regions of HIV-1.Variable processing and cross-presentation of HIV by dendritic cells and macrophages shapes CTL immunodominance and immune escape.HIV-infected sex workers with beneficial HLA-variants are potential hubs for selection of HIV-1 recombinants that may affect disease progression The immune response to a vesicular stomatitis virus vaccine vector is independent of particulate antigen secretion and protein turnover rate.

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Antigen processing influences HIV-specific cytotoxic T lymphocyte immunodominance

http://www.wikidata.org/entity/Q27655357

description

2009 nî lūn-bûn

@nan

2009 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի հունիսին հրատարակված գիտական հոդված

@hy

2009年の論文

@ja

2009年論文

@yue

2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

name

Antigen processing influences HIV-specific cytotoxic T lymphocyte immunodominance

@ast

Antigen processing influences HIV-specific cytotoxic T lymphocyte immunodominance

@en

Antigen processing influences HIV-specific cytotoxic T lymphocyte immunodominance

@nl

type

label

Antigen processing influences HIV-specific cytotoxic T lymphocyte immunodominance

@ast

Antigen processing influences HIV-specific cytotoxic T lymphocyte immunodominance

@en

Antigen processing influences HIV-specific cytotoxic T lymphocyte immunodominance

@nl

prefLabel

Antigen processing influences HIV-specific cytotoxic T lymphocyte immunodominance

@ast

Antigen processing influences HIV-specific cytotoxic T lymphocyte immunodominance

@en

Antigen processing influences HIV-specific cytotoxic T lymphocyte immunodominance

@nl

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P1433

Nature Immunology

P1476

Antigen processing influences HIV-specific cytotoxic T lymphocyte immunodominance

@en

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Andrew J McMichael

http://www.w3.org/2001/XMLSchema#string

Anne Burgevin

http://www.w3.org/2001/XMLSchema#string

Astrid K N Iversen

http://www.w3.org/2001/XMLSchema#string

Chih-hao Chang

http://www.w3.org/2001/XMLSchema#string

E Yvonne Jones

http://www.w3.org/2001/XMLSchema#string

Edmund Wee

http://www.w3.org/2001/XMLSchema#string

Hansjörg Schild

http://www.w3.org/2001/XMLSchema#string

Jan Gerstoft

http://www.w3.org/2001/XMLSchema#string

Kasper Lamberth

http://www.w3.org/2001/XMLSchema#string

Lars Fugger

http://www.w3.org/2001/XMLSchema#string

P2860

CD8+ T cell epitope-flanking mutations disrupt proteasomal processing of HIV-1 Nef.

Quantitative analysis of prion-protein degradation by constitutive and immuno-20S proteasomes indicates differences correlated with disease susceptibility.

Impact of HLA-B alleles, epitope binding affinity, functional avidity, and viral coinfection on the immunodominance of virus-specific CTL responses.

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636-46

http://www.w3.org/2001/XMLSchema#string

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scholarly article

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4477414

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P356

10.1038/NI.1728

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P433

6

http://www.w3.org/2001/XMLSchema#string

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10

http://www.w3.org/2001/XMLSchema#string

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Peter M van Endert

Guillaume Stewart-Jones

Mikkel Harndahl

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2009-06-01T00:00:00Z

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24398612

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19412183

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