Pharmacological eEF2K activation promotes cell death and inhibits cancer progression.

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Translating the anticancer properties of eEF2K.Eukaryotic elongation factor 2 kinase upregulates the expression of proteins implicated in cell migration and cancer cell metastasis.

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P2860

Pharmacological eEF2K activation promotes cell death and inhibits cancer progression.

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http://www.wikidata.org/entity/Q38749292

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2016 nî lūn-bûn

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2016年の論文

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2016年論文

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2016年論文

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2016年論文

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2016年論文

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2016年論文

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2016年论文

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2016年论文

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2016年论文

@zh-cn

name

Pharmacological eEF2K activation promotes cell death and inhibits cancer progression.

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type

Item

label

Pharmacological eEF2K activation promotes cell death and inhibits cancer progression.

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Pharmacological eEF2K activation promotes cell death and inhibits cancer progression.

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P1476

Pharmacological eEF2K activation promotes cell death and inhibits cancer progression.

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P2093

Alexey G Ryazanov

http://www.w3.org/2001/XMLSchema#string

Léa Zaffalon

http://www.w3.org/2001/XMLSchema#string

Michel Gilliet

http://www.w3.org/2001/XMLSchema#string

Olivier Demaria

http://www.w3.org/2001/XMLSchema#string

Rébecca Panes

http://www.w3.org/2001/XMLSchema#string

P2860

Identification of a new class of protein kinases represented by eukaryotic elongation factor-2 kinase

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Eukaryotic elongation factor 2 kinase as a drug target in cancer, and in cardiovascular and neurodegenerative diseases

TSC2 mediates cellular energy response to control cell growth and survival

Nelfinavir and other protease inhibitors in cancer: mechanisms involved in anticancer activity

Stimulation of the AMP-activated protein kinase leads to activation of eukaryotic elongation factor 2 kinase and to its phosphorylation at a novel site, serine 398

The eEF2 kinase confers resistance to nutrient deprivation by blocking translation elongation

Drug discovery using chemical systems biology: weak inhibition of multiple kinases may contribute to the anti-cancer effect of nelfinavir

Drug repositioning: identifying and developing new uses for existing drugs

mTOR and cancer: many loops in one pathway.

P304

1471-1484

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scholarly article

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10.15252/EMBR.201642194

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Fabio Martinon

Aude De Gassart

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2016-08-29T00:00:00Z

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27572820

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5048377

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Pharmacological eEF2K activation promotes cell death and inhibits cancer progression.

about

P2860

P2860

Pharmacological eEF2K activation promotes cell death and inhibits cancer progression.

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P1433

P1476

P2093

P2860

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P433

P478

P50

P577

P698

P932