SAMHD1 controls cell cycle status, apoptosis and HIV-1 infection in monocytic THP-1 cells.
about
SAMHD1 protects cancer cells from various nucleoside-based antimetabolites.MicroRNA-181 contributes to downregulation of SAMHD1 expression in CD4+ T-cells derived from Sèzary syndrome patients.Gene Editing Approaches against Viral Infections and Strategy to Prevent Occurrence of Viral Escape.The SAMHD1 dNTP Triphosphohydrolase Is Controlled by a Redox Switch.Single-Stranded Nucleic Acids Bind to the Tetramer Interface of SAMHD1 and Prevent Formation of the Catalytic Homotetramer.Mechanisms of HIV-1 Control.A CRISPR/Cas9 approach reveals that the polymerase activity of DNA polymerase β is dispensable for HIV-1 infection in dividing and nondividing cellsInhibition of Vpx-Mediated SAMHD1 and Vpr-Mediated Host Helicase Transcription Factor Degradation by Selective Disruption of Viral CRL4 (DCAF1) E3 Ubiquitin Ligase AssemblyExogenous expression of SAMHD1 inhibits proliferation and induces apoptosis in cutaneous T-cell lymphoma-derived HuT78 cells.A Putative Cyclin-binding Motif in Human SAMHD1 Contributes to Protein Phosphorylation, Localization, and Stability.Roles of SAMHD1 in antiviral defense, autoimmunity and cancer.SAMHD1 enhances nucleoside-analogue efficacy against HIV-1 in myeloid cells.Interferons Induce Expression of SAMHD1 in Monocytes through Down-regulation of miR-181a and miR-30a.SAMHD1 acetylation enhances its deoxynucleotide triphosphohydrolase activity and promotes cancer cell proliferation.CRISPR/Cas9-Advancing Orthopoxvirus Genome Editing for Vaccine and Vector Development.Regulation of CD4 Receptor and HIV-1 Entry by MicroRNAs-221 and -222 during Differentiation of THP-1 Cells.A Cyclin-binding Motif in Human SAMHD1 Is Required for Its HIV-1 Restriction, dNTPase Activity, Tetramer Formation, and Efficient Phosphorylation.A CRISPR screen for factors regulating SAMHD1 degradation identifies IFITMs as potent inhibitors of lentiviral particle delivery.SAMHD1 suppresses innate immune responses to viral infections and inflammatory stimuli by inhibiting the NF-κB and interferon pathways.SAMHD1: Recurring roles in cell cycle, viral restriction, cancer, and innate immunity.Dephosphorylation of the HIV-1 restriction factor SAMHD1 is mediated by PP2A-B55α holoenzymes during mitotic exit.SAMHD1 Impairs HIV-1 Gene Expression and Negatively Modulates Reactivation of Viral Latency in CD4+ T-cells.SAMHD1 modulates in vitro proliferation of acute myeloid leukemia-derived THP-1 cells through the PI3K-Akt-p27 axisInterplay of ancestral non-primate lentiviruses with the virus-restricting SAMHD1 proteins of their hosts
P2860
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P2860
SAMHD1 controls cell cycle status, apoptosis and HIV-1 infection in monocytic THP-1 cells.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
SAMHD1 controls cell cycle sta ...... tion in monocytic THP-1 cells.
@en
type
label
SAMHD1 controls cell cycle sta ...... tion in monocytic THP-1 cells.
@en
prefLabel
SAMHD1 controls cell cycle sta ...... tion in monocytic THP-1 cells.
@en
P2093
P2860
P1433
P1476
SAMHD1 controls cell cycle sta ...... tion in monocytic THP-1 cells.
@en
P2093
Caitlin Shepard
Corine St Gelais
Dong-Hyun Kim
Edward M Kennedy
Joseph A Hollenbaugh
Michele B Daly
Serena Bonifati
Sun Hee Kim
P2860
P304
P356
10.1016/J.VIROL.2016.05.002
P407
P577
2016-05-13T00:00:00Z