Synthesis, molecular modeling and NAD(P)H:quinone oxidoreductase 1 inducer activity of novel 2-phenylquinazolin-4-amine derivatives.

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Synthesis, molecular modeling and NAD(P)H:quinone oxidoreductase 1 inducer activity of novel 2-phenylquinazolin-4-amine derivatives.

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2016 nî lūn-bûn

@nan

2016年の論文

@ja

2016年論文

@yue

2016年論文

@zh-hant

2016年論文

@zh-hk

2016年論文

@zh-mo

2016年論文

@zh-tw

2016年论文

@wuu

2016年论文

@zh

2016年论文

@zh-cn

name

Synthesis, molecular modeling ...... uinazolin-4-amine derivatives.

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type

Item

label

Synthesis, molecular modeling ...... uinazolin-4-amine derivatives.

@en

prefLabel

Synthesis, molecular modeling ...... uinazolin-4-amine derivatives.

@en

P1476

Synthesis, molecular modeling ...... uinazolin-4-amine derivatives.

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P2093

Mansour S Alsaid

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Maureen Higgins

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Mostafa M Ghorab

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Nehal H Elghazawy

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P2860

Reactive oxygen species: role in the development of cancer and various chronic conditions

Small molecules inhibit the interaction of Nrf2 and the Keap1 Kelch domain through a non-covalent mechanism

Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants

Anti-inflammatory Effect of a Cell-Penetrating Peptide Targeting the Nrf2/Keap1 Interaction

Small molecule modulators of Keap1-Nrf2-ARE pathway as potential preventive and therapeutic agents

The antioxidant defense system Keap1-Nrf2 comprises a multiple sensing mechanism for responding to a wide range of chemical compounds

Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway

Keap1 perceives stress via three sensors for the endogenous signaling molecules nitric oxide, zinc, and alkenals.

Discovery of potent, novel Nrf2 inducers via quantum modeling, virtual screening, and in vitro experimental validation.

Discovery of a small-molecule inhibitor and cellular probe of Keap1-Nrf2 protein-protein interaction

P304

1612-1618

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P31

scholarly article

P356

10.3109/14756366.2016.1158714

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P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

Albena T Dinkova-Kostova

Abdelaaty A Shahat

Reem K Arafa

P577

2016-04-07T00:00:00Z

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P5875

299989526

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P698

27052554

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