about
Selective non-nucleoside inhibitors of human DNA methyltransferases active in cancer including in cancer stem cells.Emerging approaches for histone deacetylase inhibitor drug discovery.DNA Methyltransferases Inhibitors from Natural Sources.Effect of Class II HDAC inhibition on glutamate transporter expression and survival in SOD1-ALS mice.Metabolite profiling of ascidian Styela plicata using LC-MS with multivariate statistical analysis and their antitumor activity.Epi-drugs in combination with immunotherapy: a new avenue to improve anticancer efficacyLSD1 inhibitors: a patent review (2010-2015).1,4-Dihydropyridines Active on the SIRT1/AMPK Pathway Ameliorate Skin Repair and Mitochondrial Function and Exhibit Inhibition of Proliferation in Cancer Cells.MC1568 inhibits HDAC6/8 activity and influenza A virus replication in lung epithelial cells: role of Hsp90 acetylation.EZH2 inhibitors: a patent review (2014-2016).Novel histone deacetylase inhibitors induce growth arrest, apoptosis, and differentiation in sarcoma cancer stem cells.The histone methyltransferase EZH2 as a druggable target in SHH medulloblastoma cancer stem cells.Histone deacetylase inhibitors restore IL-10 expression in lipopolysaccharide-induced cell inflammation and reduce IL-1β and IL-6 production in breast silicone implant in C57BL/6J wild-type murine model.Towards the development of activity-based probes for detection of lysine-specific demethylase-1 activity.Novel coumarin- and quinolinone-based polycycles as cell division cycle 25-A and -C phosphatases inhibitors induce proliferation arrest and apoptosis in cancer cells.Pyrazole-based inhibitors of enhancer of zeste homologue 2 induce apoptosis and autophagy in cancer cells.Trends of LSD1 inhibitors in viral infections.HDAC1 inhibition by MS-275 in mesothelial cells limits cellular invasion and promotes MMT reversal.A Quinoline-Based DNA Methyltransferase Inhibitor as a Possible Adjuvant in Osteosarcoma TherapyNucleocytoplasmic export of HDAC5 and SIRT2 downregulation: two epigenetic mechanisms by which antidepressants enhance synaptic plasticity markersSix Years (2012-2018) of Researches on Catalytic EZH2 Inhibitors: The Boom of the 2-Pyridone CompoundsNovel benzofuran–chromone and –coumarin derivatives: synthesis and biological activity in K562 human leukemia cellsApplication of Small Epigenetic Modulators in Pediatric MedulloblastomaIdentification of a novel quinoline-based DNA demethylating compound highly potent in cancer cellsThe emerging role of epigenetics in human autoimmune disordersNovel inhibitors of human histone deacetylases: design, synthesis and bioactivity of 3-alkenoylcoumarinesEffects of Class II-Selective Histone Deacetylase Inhibitor on Neuromuscular Function and Disease Progression in SOD1-ALS MiceTranylcypromine-Based LSD1 Inhibitors: Structure-Activity Relationships, Antiproliferative Effects in Leukemia, and Gene Target ModulationNovel Quinoline Compounds Active in Cancer Cells through Coupled DNA Methyltransferase Inhibition and DegradationDevelopment of alkyl glycerone phosphate synthase inhibitors: Structure-activity relationship and effects on ether lipids and epithelial-mesenchymal transition in cancer cellsSirtuin modulators: where are we now? A review of patents from 2015 to 2019Discovery of the First Human Arylsulfatase A Reversible Inhibitor Impairing Mouse Oocyte FertilizationAcute and chronic neurobehavioral effects of the designer drug and bath salt constituent 3,4-methylenedioxypyrovalerone in the ratAmphetamine and the Smart Drug 3,4-Methylenedioxypyrovalerone (MDPV) Induce Generalization of Fear Memory in RatsDetrimental effects of the 'bath salt' methylenedioxypyrovalerone on social play behavior in male rats
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P50
description
hulumtues
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Clemens Zwergel
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Clemens Zwergel
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Clemens Zwergel
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Clemens Zwergel
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Clemens Zwergel
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Clemens Zwergel
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Clemens Zwergel
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Clemens Zwergel
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Clemens Zwergel
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Clemens Zwergel
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Clemens Zwergel
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Clemens Zwergel
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Clemens Zwergel
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Clemens Zwergel
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Clemens Zwergel
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P106
P1153
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P21
P31
P496
0000-0002-3097-0003