Therapeutic targeting of complement to modify disease course and improve outcomes in neurological conditions.
about
New milestones ahead in complement-targeted therapy.Complement C5a-C5aR1 signalling drives skeletal muscle macrophage recruitment in the hSOD1G93A mouse model of amyotrophic lateral sclerosis.IVIg attenuates complement and improves spinal cord injury outcomes in mice.The renaissance of complement therapeutics.Novel mechanisms and functions of complement.Complement C5a Receptor 1 Exacerbates the Pathophysiology of N. meningitidis Sepsis and Is a Potential Target for Disease Treatment.Pharmacological inhibition of complement C5a-C5a1 receptor signalling ameliorates disease pathology in the hSOD1G93A mouse model of amyotrophic lateral sclerosis.Complement components are upregulated and correlate with disease progression in the TDP-43Q331K mouse model of amyotrophic lateral sclerosis.Development and validation of a LC-MS/MS assay for pharmacokinetic studies of complement C5a receptor antagonists PMX53 and PMX205 in mice.
P2860
Q33602320-B8059FAE-3CA0-4A9F-A516-F0432379A2B4Q33756216-8E54E464-0601-4169-A242-8A1326887841Q37062115-8E107A57-296F-41BD-AD1B-DEFB539F0AB9Q47336749-7BB97544-D871-4ED5-BA18-5AAABE9A2F4EQ47396517-2753C04A-3EA8-4ADA-AB0B-9EE24D14679AQ48181626-230BBB17-4793-4564-BB61-AFB2E9A42270Q48304802-59065391-AA27-49D4-B129-29AA2875B3FFQ54958681-A46933DE-2A28-45C1-8E2B-E4A3D529093DQ55311354-F8B88E3E-E06C-4FD5-A233-9787ECD40FB9
P2860
Therapeutic targeting of complement to modify disease course and improve outcomes in neurological conditions.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Therapeutic targeting of compl ...... es in neurological conditions.
@en
type
label
Therapeutic targeting of compl ...... es in neurological conditions.
@en
prefLabel
Therapeutic targeting of compl ...... es in neurological conditions.
@en
P50
P1476
Therapeutic targeting of compl ...... es in neurological conditions.
@en
P304
P356
10.1016/J.SMIM.2016.03.015
P577
2016-04-02T00:00:00Z