Functional genetic screens for enhancer elements in the human genome using CRISPR-Cas9.
about
CRISPR-Cas9: from Genome Editing to Cancer ResearchUsing CRISPR/Cas to study gene function and model disease in vivoEditing the Neuronal Genome: a CRISPR View of Chromatin Regulation in Neuronal Development, Function, and PlasticityTranscription Impacts the Efficiency of mRNA Translation via Co-transcriptional N6-adenosine Methylation.Systematic mapping of functional enhancer-promoter connections with CRISPR interference.CRISPR/Cas9 targeting events cause complex deletions and insertions at 17 sites in the mouse genome.Applications of CRISPR technologies in research and beyond.Genome-scale CRISPR-Cas9 knockout and transcriptional activation screeningHigh-resolution interrogation of functional elements in the noncoding genomeMapping regulatory elements.CRISPR library designer (CLD): software for multispecies design of single guide RNA librariesSystematic Functional Dissection of Common Genetic Variation Affecting Red Blood Cell TraitsGenome-scale deletion screening of human long non-coding RNAs using a paired-guide RNA CRISPR-Cas9 library.Directed evolution using dCas9-targeted somatic hypermutation in mammalian cells.CRISPR/Cas9-The ultimate weapon to battle infectious diseases?Scalable Design of Paired CRISPR Guide RNAs for Genomic DeletionGuideScan software for improved single and paired CRISPR guide RNA designFunctional interrogation of non-coding DNA through CRISPR genome editing.CRISPR-Cas9 epigenome editing enables high-throughput screening for functional regulatory elements in the human genome.A new class of temporarily phenotypic enhancers identified by CRISPR/Cas9-mediated genetic screening.Applications of CRISPR genome editing technology in drug target identification and validation.CRISPR: express delivery to any DNA address.The expanding footprint of CRISPR/Cas9 in the plant sciences.CRISPR/Cas9 genome editing in human pluripotent stem cells: Harnessing human genetics in a dish.Deciphering the function of non-coding RNAs in prostate cancer.ChIP-seq in studying epigenetic mechanisms of disease and promoting precision medicine: progresses and future directions.CRISPR Screens to Discover Functional Noncoding Elements.The Estrogen Receptor α-Cistrome Beyond Breast Cancer.Applications of CRISPR Genome Engineering in Cell Biology.An Emerging Regulatory Landscape for Skeletal Development.From profiles to function in epigenomics.Cornerstones of CRISPR-Cas in drug discovery and therapy.Regulatory elements in molecular networks.Application of CRISPR/Cas9 to the study of brain development and neuropsychiatric disease.Recent advances in functional perturbation and genome editing techniques in studying sea urchin development.Modeling human disease in rodents by CRISPR/Cas9 genome editing.Recent advances in high-throughput approaches to dissect enhancer functionDiscovery of stimulation-responsive immune enhancers with CRISPR activation.CRISPR-FOCUS: A web server for designing focused CRISPR screening experiments.Dense sgRNA Library Construction Using a Molecular Chipper Approach
P2860
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P2860
Functional genetic screens for enhancer elements in the human genome using CRISPR-Cas9.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Functional genetic screens for enhancer elements in the human genome using CRISPR-Cas9.
@en
type
label
Functional genetic screens for enhancer elements in the human genome using CRISPR-Cas9.
@en
prefLabel
Functional genetic screens for enhancer elements in the human genome using CRISPR-Cas9.
@en
P2093
P50
P356
P1433
P1476
Functional genetic screens for enhancer elements in the human genome using CRISPR-Cas9.
@en
P2093
Alejandro P Ugalde
Ekaterina Nevedomskaya
Ksenia Myacheva
P2888
P304
P356
10.1038/NBT.3450
P577
2016-01-11T00:00:00Z
P5875
P6179
1041137755