Regulation of breast tumorigenesis through acid sensors.
about
Potential Roles of Amiloride-Sensitive Sodium Channels in Cancer DevelopmentERK-mediated NF-κB activation through ASIC1 in response to acidosisOver-expression of ASIC1a promotes proliferation via activation of the β-catenin/LEF-TCF axis and is associated with disease outcome in liver cancerASIC2a-dependent increase of ASIC3 surface expression enhances the sustained component of the currents.Acid-sensing ion channels contribute to the effect of extracellular acidosis on proliferation and migration of A549 cells.ASIC1a mediates the drug resistance of human hepatocellular carcinoma via the Ca2+/PI3-kinase/AKT signaling pathway.ASIC1 and ASIC3 contribute to acidity-induced EMT of pancreatic cancer through activating Ca2+/RhoA pathway.The acid-sensing ion channel, ASIC2, promotes invasion and metastasis of colorectal cancer under acidosis by activating the calcineurin/NFAT1 axis.Glioblastoma cancer stem cell lines express functional acid sensing ion channels ASIC1a and ASIC3.TRPM5 mediates acidic extracellular pH signaling and TRPM5 inhibition reduces spontaneous metastasis in mouse B16-BL6 melanoma cells.Nuclear galectin-1-FOXP3 interaction dampens the tumor-suppressive properties of FOXP3 in breast cancer.A temporal examination of calcium signaling in cancer- from tumorigenesis, to immune evasion, and metastasis.
P2860
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P2860
Regulation of breast tumorigenesis through acid sensors.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Regulation of breast tumorigenesis through acid sensors.
@en
type
label
Regulation of breast tumorigenesis through acid sensors.
@en
prefLabel
Regulation of breast tumorigenesis through acid sensors.
@en
P2093
P2860
P356
P1433
P1476
Regulation of breast tumorigenesis through acid sensors
@en
P2093
M R Pabbidi
P2860
P2888
P304
P356
10.1038/ONC.2015.477
P407
P50
P577
2015-12-21T00:00:00Z
P6179
1017881479