Hypercapnia modulates cAMP signalling and cystic fibrosis transmembrane conductance regulator-dependent anion and fluid secretion in airway epithelia.

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Spaceflight induced changes in the human proteome.

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Q38435061-10A4B468-F23E-4E2F-8B84-428E3963E531

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Hypercapnia modulates cAMP signalling and cystic fibrosis transmembrane conductance regulator-dependent anion and fluid secretion in airway epithelia.

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Hypercapnia modulates cAMP sig ...... secretion in airway epithelia.

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Hypercapnia modulates cAMP sig ...... secretion in airway epithelia.

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Hypercapnia modulates cAMP sig ...... secretion in airway epithelia.

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Hypercapnia modulates cAMP sig ...... secretion in airway epithelia

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Bernard Verdon

http://www.w3.org/2001/XMLSchema#string

James P Garnett

http://www.w3.org/2001/XMLSchema#string

Mark J Turner

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Martin J Cann

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Robert Tarran

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Salam H Ibrahim

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Waseema Patel

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P2860

Cytosolic adenylyl cyclase defines a unique signaling molecule in mammals

Structure of the adenylyl cyclase catalytic core

Crystal structure of the catalytic domains of adenylyl cyclase in a complex with Gsalpha.GTPgammaS

IRBIT coordinates epithelial fluid and HCO3- secretion by stimulating the transporters pNBC1 and CFTR in the murine pancreatic duct

Central CO2 chemoreception and integrated neural mechanisms of cardiovascular and respiratory control.

AMP-activated protein kinase regulates CO2-induced alveolar epithelial dysfunction in rats and human cells by promoting Na,K-ATPase endocytosis

Bicarbonate and functional CFTR channel are required for proper mucin secretion and link cystic fibrosis with its mucus phenotype.

High CO2 levels impair alveolar epithelial function independently of pH.

Compartmentalized cyclic adenosine 3',5'-monophosphate at the plasma membrane clusters PDE3A and cystic fibrosis transmembrane conductance regulator into microdomains.

Soluble adenylyl cyclase as an evolutionarily conserved bicarbonate sensor.

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scholarly article

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10.1113/JP271309

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English

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594

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Chris Ward

Michael A Gray

Vinciane Saint-Criq

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2015-12-20T00:00:00Z

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26574187

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cystic fibrosis

transmembrane protein

hypercapnia

P932

4799982

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Hypercapnia modulates cAMP signalling and cystic fibrosis transmembrane conductance regulator-dependent anion and fluid secretion in airway epithelia.

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P2860

P2860

Hypercapnia modulates cAMP signalling and cystic fibrosis transmembrane conductance regulator-dependent anion and fluid secretion in airway epithelia.

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