Loss of BAP1 function leads to EZH2-dependent transformation.
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DUBbing Cancer: Deubiquitylating Enzymes Involved in Epigenetics, DNA Damage and the Cell Cycle As Therapeutic TargetsImplementing Genome-Driven Oncology.Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular Profiles.ASXL2 is essential for haematopoiesis and acts as a haploinsufficient tumour suppressor in leukemia.Novel systemic therapy against malignant pleural mesothelioma.BAP1, a tumor suppressor gene driving malignant mesothelioma.Targeting the epigenome in malignant pleural mesotheliomaUpregulation of HLA Expression in Primary Uveal Melanoma by Infiltrating LeukocytesEzh2 Controls an Early Hematopoietic Program and Growth and Survival Signaling in Early T Cell Precursor Acute Lymphoblastic LeukemiaEpigenetics of hematopoiesis and hematological malignancies.The emerging role of deubiquitinating enzymes in genomic integrity, diseases, and therapeuticsBAP1 dependent expression of long non-coding RNA NEAT-1 contributes to sensitivity to gemcitabine in cholangiocarcinomaGenomic profiling of malignant peritoneal mesothelioma reveals recurrent alterations in epigenetic regulatory genes BAP1, SETD2, and DDX3X.Epithelioid peritoneal mesothelioma: a hybrid phenotype within a mesenchymal-epithelial/epithelial-mesenchymal transition framework.Asxl1 deficiency in embryonic fibroblasts leads to cellular senescence via impairment of the AKT-E2F pathway and Ezh2 inactivation.Epigenetic Medicinal Chemistry.Turning the tide in myelodysplastic/myeloproliferative neoplasms.Loss of tumor suppressor KDM6A amplifies PRC2-regulated transcriptional repression in bladder cancer and can be targeted through inhibition of EZH2.A catalogue of treatment and technologies for malignant pleural mesothelioma.An oncogenic Ezh2 mutation induces tumors through global redistribution of histone 3 lysine 27 trimethylation.Update on Metastatic Uveal Melanoma: Progress and Challenges.Epigenetic balance of gene expression by Polycomb and COMPASS families.Role of the Polycomb Repressive Complex 2 (PRC2) in Transcriptional Regulation and Cancer.H3K27 Methylation: A Focal Point of Epigenetic Deregulation in Cancer.The Role of Additional Sex Combs-Like Proteins in Cancer.Dysregulation of histone methyltransferases in breast cancer - Opportunities for new targeted therapies?A chemical probe toolbox for dissecting the cancer epigenome.BAP1 mutations in high-grade meningioma: implications for patient care.Epigenetic dysregulation of hematopoietic stem cells and preleukemic state.Malignant Mesothelioma: Time to Translate?Novel insights into mesothelioma biology and implications for therapy.KDM6B histone demethylase is an epigenetic regulator of estrogen receptor β expression in human pleural mesothelioma.Chemosensitive Relapse in Small Cell Lung Cancer Proceeds through an EZH2-SLFN11 Axis.Diagnostic utility of BAP1 and EZH2 expression in malignant mesothelioma.NeuCode Proteomics Reveals Bap1 Regulation of Metabolism.Comprehensive multiregional analysis of molecular heterogeneity in bladder cancer.Integrative analysis of genomic and epigenomic regulation of the transcriptome in liver cancer.Modulating BAP1 expression affects ROS homeostasis, cell motility and mitochondrial function.Malignant Mesothelioma, BAP1 Immunohistochemistry, and VEGFA: Does BAP1 Have Potential for Early Diagnosis and Assessment of Prognosis?Germline and somatic BAP1 mutations in high-grade rhabdoid meningiomas.
P2860
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P2860
Loss of BAP1 function leads to EZH2-dependent transformation.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Loss of BAP1 function leads to EZH2-dependent transformation.
@en
type
label
Loss of BAP1 function leads to EZH2-dependent transformation.
@en
prefLabel
Loss of BAP1 function leads to EZH2-dependent transformation.
@en
P2093
P2860
P50
P356
P1433
P1476
Loss of BAP1 function leads to EZH2-dependent transformation.
@en
P2093
Alan Chramiec
Ari Melnick
Barbara Spitzer
Efthymia Papalexi
Emma H Doud
Heike Keilhack
Inna Khodos
Jean-Baptiste Micol
John E Campbell
P2860
P2888
P304
P356
10.1038/NM.3947
P407
P577
2015-10-05T00:00:00Z