Chromosomal instability, tolerance of mitotic errors and multidrug resistance are promoted by tetraploidization in human cells.
about
BCL9L Dysfunction Impairs Caspase-2 Expression Permitting Aneuploidy Tolerance in Colorectal CancerTranscriptome analysis of tetraploid cells identifies cyclin D2 as a facilitator of adaptation to genome doubling in the presence of p53Lung Basal Stem Cells Rapidly Repair DNA Damage Using the Error-Prone Nonhomologous End-Joining PathwayIdentification of genes that are essential to restrict genome duplication to once per cell divisionExperimental Evolution Reveals Interplay between Sch9 and Polyploid Stability in YeastSelective advantage of trisomic human cells cultured in non-standard conditionsRNA- binding protein Stau2 is important for spindle integrity and meiosis progression in mouse oocytes.Links between DNA Replication, Stem Cells and Cancer.Chromosome nondisjunction during bipolar mitoses of binucleated intermediates promote aneuploidy formation along with multipolar mitoses rather than chromosome loss in micronuclei induced by asbestos.The Consequences of Chromosome Segregation Errors in Mitosis and Meiosis.Centrosome amplification, chromosomal instability and cancer: mechanistic, clinical and therapeutic issues.Stable aneuploid tumors cells are more sensitive to TTK inhibition than chromosomally unstable cell lines.Establishment of proliferative tetraploid cells from telomerase-immortalized normal human fibroblasts.Pan-cancer analysis distinguishes transcriptional changes of aneuploidy from proliferation.The Role of Aneuploidy in Cancer Evolution.Tetraploidy and CIN: a dangerous combinationTumor-Associated Macrophages Suppress the Cytotoxic Activity of Antimitotic AgentsInvestigating cytokinesis failure as a strategy in cancer therapyLearning causal networks with latent variables from multivariate information in genomic data.The ISWI ATPase Smarca5 (Snf2h) Is Required for Proliferation and Differentiation of Hematopoietic Stem and Progenitor Cells.Aneuploidy, TP53 mutation, and amplification of MYC correlate with increased intratumor heterogeneity and poor prognosis of breast cancer patients.Determinants and clinical implications of chromosomal instability in cancer.Mammalian Cells Undergo Endoreduplication in Response to Lactic Acidosis.Near-tetraploid cancer cells show chromosome instability triggered by replication stress and exhibit enhanced invasiveness.Establishment of Proliferative Tetraploid Cells from Nontransformed Human Fibroblasts.Manipulation of Ploidy in Caenorhabditis elegans.Quantitative proteomic and phosphoproteomic comparison of human colon cancer DLD-1 cells differing in ploidy and chromosome stability.A Soft Microenvironment Protects from Failure of Midbody Abscission and Multinucleation Downstream of the EMT-Promoting Transcription Factor Snail.Tetraploidy in cancer and its possible link to agingCentrosome aberrations and chromosome instability contribute to tumorigenesis and intra-tumor heterogeneity
P2860
Q28468367-04D89E32-BF28-4BE4-BA8B-ADF245ACB202Q28552677-BFF99356-CCD0-4216-9EAB-2DC3B09CBAFBQ28818153-1AEBE2B8-F21A-4DD4-AC08-3DFE08F13AE6Q28820756-47E12C5C-49C3-43F1-9331-8E4424489A76Q28822236-CAC66ED1-76FE-4444-BD46-A35055B99A95Q36666738-54FB694C-6DF2-44F8-A05B-A20E93464597Q37317059-13DC8241-A596-4FC9-BCD2-E4502F613560Q37676222-C6C3D470-08BD-4C54-AF78-6CB199FB0488Q37706869-AE58A7E1-E30E-425F-BC40-E0DC11104CE7Q37728190-4E09D3CB-40EA-4508-BAA9-AC2823410A9FQ38662334-632EDDB8-C311-4FF8-96F2-86DAB8313B81Q38707261-7F911E93-0C4F-44B2-B4AB-A23E5DBDB782Q38790885-A89B682B-2C54-487C-9A2E-72E939A97D46Q38892431-D6061CC1-7F29-4D34-B4DB-C2C20E185B02Q39066291-C5182458-F230-4889-BEBD-0B8CB4A8C6B8Q39984199-EF1715FC-18DF-4F2F-BC89-A898DFB4DEBDQ41688200-DD2B42FD-D377-4C63-AB37-00C6C01666C5Q41887009-BF2754D4-8F01-4ED8-9A8C-9D7842610A04Q42696657-D17AFFB0-6339-4A26-92D4-4D1CF7B0CE4CQ48146234-44D326F3-7568-4E67-BCEC-3BBD79430776Q48225335-00B07145-9066-4C5D-932E-AEFB9AEE3349Q49347721-24E355B6-2A3F-40F3-996B-5D3857CDA779Q49352105-592EFD4D-314D-40DB-98F8-94BC7BBA6901Q49921097-6F89F34E-97E9-46ED-9CD1-CCAA054A4006Q50935885-396AB066-36CB-4F2D-B438-9C899EF7D73EQ51731078-8B27BF00-0E9E-4AAC-8313-DCB4A37E042AQ52729447-8EB5BCAC-2CF3-464A-B898-9DF3298E8A9CQ52730282-14425BBE-AB16-43CC-97F4-F201C2BA086BQ57662446-35626771-4F3B-4210-A904-31BE6CF7DEFFQ58132668-934823DA-BEA8-4F5B-B0D1-02FFF5B5557E
P2860
Chromosomal instability, tolerance of mitotic errors and multidrug resistance are promoted by tetraploidization in human cells.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Chromosomal instability, toler ...... raploidization in human cells.
@en
type
label
Chromosomal instability, toler ...... raploidization in human cells.
@en
prefLabel
Chromosomal instability, toler ...... raploidization in human cells.
@en
P2093
P2860
P1433
P1476
Chromosomal instability, toler ...... raploidization in human cells.
@en
P2093
Anastasia Y Kuznetsova
Christian Kuffer
Giuliana K Moeller
Guido J R Zaman
Jeroen A D M de Roos
Katarzyna Seget
Milena Dürrbaum
Mirjam S de Pagter
Stefan Müller
Wigard P Kloosterman
P2860
P304
P356
10.1080/15384101.2015.1068482
P577
2015-07-07T00:00:00Z