The MDM2-inhibitor Nutlin-3 synergizes with cisplatin to induce p53 dependent tumor cell apoptosis in non-small cell lung cancer
about
The role of p53 in cancer drug resistance and targeted chemotherapyPreclinical data on the combination of cisplatin and anti-CD70 therapy in non-small cell lung cancer as an excellent match in the era of combination therapy.Combination wt-p53 and MicroRNA-125b Transfection in a Genetically Engineered Lung Cancer Model Using Dual CD44/EGFR-targeting Nanoparticles.Novel MDM2 inhibitor SAR405838 (MI-773) induces p53-mediated apoptosis in neuroblastoma.Amplification of ACK1 promotes gastric tumorigenesis via ECD-dependent p53 ubiquitination degradation.MDM2 SNP309 and SNP285 Act as Negative Prognostic Markers for Non-small Cell Lung Cancer Adenocarcinoma Patients.Systematic Drug Screening Identifies Tractable Targeted Combination Therapies in Triple-Negative Breast Cancer.P53 suppresses ribonucleotide reductase via inhibiting mTORC1.Restoration of p53 using the novel MDM2-p53 antagonist APG115 suppresses dedifferentiated papillary thyroid cancer cells.Targeting cyclophilin-D by compound 19 protects neuronal cells from oxygen glucose deprivation/re-oxygenation.Targeting signaling and apoptotic pathways involved in chemotherapeutic drug-resistance of hematopoietic cells.Ginseng Rh2 protects endometrial cells from oxygen glucose deprivation/re-oxygenation.Hypoxia-Induced Cisplatin Resistance in Non-Small Cell Lung Cancer Cells Is Mediated by HIF-1α and Mutant p53 and Can Be Overcome by Induction of Oxidative Stress.
P2860
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P2860
The MDM2-inhibitor Nutlin-3 synergizes with cisplatin to induce p53 dependent tumor cell apoptosis in non-small cell lung cancer
description
2015 nî lūn-bûn
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name
The MDM2-inhibitor Nutlin-3 sy ...... in non-small cell lung cancer
@en
type
label
The MDM2-inhibitor Nutlin-3 sy ...... in non-small cell lung cancer
@en
prefLabel
The MDM2-inhibitor Nutlin-3 sy ...... in non-small cell lung cancer
@en
P2093
P2860
P50
P356
P1433
P1476
The MDM2-inhibitor Nutlin-3 sy ...... in non-small cell lung cancer
@en
P2093
Christian Rolfo
Christophe Deben
Jan Van Meerbeeck
Karen Zwaenepoel
Marc Peeters
Patrick Pauwels
P2860
P304
22666-22679
P356
10.18632/ONCOTARGET.4433
P407
P577
2015-06-10T00:00:00Z