Integration of Hedgehog and mutant FLT3 signaling in myeloid leukemia.
about
Update on rational targeted therapy in AMLHedgehog Signaling in the Maintenance of Cancer Stem CellsCombined inhibition of GLI and FLT3 signaling leads to effective anti-leukemic effects in human acute myeloid leukemia.Acute myeloid leukemia - strategies and challenges for targeting oncogenic Hedgehog/GLI signalingDOCK2 interacts with FLT3 and modulates the survival of FLT3-expressing leukemia cells.FLT3 Inhibitors in Acute Myeloid Leukemia: Current Status and Future Directions.Small-molecule Hedgehog inhibitor attenuates the leukemia-initiation potential of acute myeloid leukemia cells.GLI3 repressor determines Hedgehog pathway activation and is required for response to SMO antagonist glasdegib in AML.GLI1 inhibitor GANT61 exhibits antitumor efficacy in T-cell lymphoma cells through down-regulation of p-STAT3 and SOCS3.Rational for targeting the hedgehog signalling pathway in acute myeloid leukemia with FLT3 mutation
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Integration of Hedgehog and mutant FLT3 signaling in myeloid leukemia.
description
2015 nî lūn-bûn
@nan
2015年の論文
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2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
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2015年论文
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name
Integration of Hedgehog and mutant FLT3 signaling in myeloid leukemia.
@en
type
label
Integration of Hedgehog and mutant FLT3 signaling in myeloid leukemia.
@en
prefLabel
Integration of Hedgehog and mutant FLT3 signaling in myeloid leukemia.
@en
P2093
P2860
P1476
Integration of Hedgehog and mutant FLT3 signaling in myeloid leukemia
@en
P2093
Akil A Merchant
Bruce Douglas Smith
Craig D Peacock
David L Huso
David Neil Watkins
Donald Small
Emily Chang
Karen McGovern
P2860
P304
P356
10.1126/SCITRANSLMED.AAA5731
P407
P577
2015-06-01T00:00:00Z