IDH1 Mutation Induces Reprogramming of Pyruvate Metabolism.
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Molecular Imaging of Metabolic Reprograming in Mutant IDH CellsMagnetic Resonance (MR) Metabolic Imaging in Glioma.MR Molecular Imaging of Brain Cancer Metabolism Using Hyperpolarized 13C Magnetic Resonance Spectroscopy.IDH1 R132H mutation regulates glioma chemosensitivity through Nrf2 pathway.Molecular Pathways: Isocitrate Dehydrogenase Mutations in Cancer.Hyperpolarized (13)C MR imaging detects no lactate production in mutant IDH1 gliomas: Implications for diagnosis and response monitoring.A Canonical Correlation Analysis of AIDS Restriction Genes and Metabolic Pathways Identifies Purine Metabolism as a Key Cooperator.Chemosensitivity of IDH1-Mutated Gliomas Due to an Impairment in PARP1-Mediated DNA Repair.Emerging Approaches for Targeting Metabolic Vulnerabilities in Malignant Glioma.In silico gene expression analysis reveals glycolysis and acetate anaplerosis in IDH1 wild-type glioma and lactate and glutamate anaplerosis in IDH1-mutated gliomaMetabolic reprogramming of pyruvate dehydrogenase is essential for the proliferation of glioma cells expressing mutant IDH1.Metabolic Reprogramming in Glioma.Mutant IDH1 expression is associated with down-regulation of monocarboxylate transporters.Cellular Metabolism and Dose Reveal Carnitine-Dependent and -Independent Mechanisms of Butyrate Oxidation in Colorectal Cancer Cells.MicroRNA Regulation of Glycolytic Metabolism in Glioblastoma.The Alkylating Chemotherapeutic Temozolomide Induces Metabolic Stress in IDH1-Mutant Cancers and Potentiates NAD+ Depletion-Mediated Cytotoxicity.Expression Levels and Localizations of DVL3 and sFRP3 in Glioblastoma.Reverse engineering the cancer metabolic network using flux analysis to understand drivers of human disease.Altered metabolic landscape in IDH-mutant gliomas affects phospholipid, energy, and oxidative stress pathways.Therapeutic Targeting of the Pyruvate Dehydrogenase Complex/Pyruvate Dehydrogenase Kinase (PDC/PDK) Axis in Cancer.Metabolomic profiling identifies distinct phenotypes for ASS1 positive and negative GBM.Metabolism, Activity, and Targeting of D- and L-2-Hydroxyglutarates.Consumption of NADPH for 2-HG Synthesis Increases Pentose Phosphate Pathway Flux and Sensitizes Cells to Oxidative Stress.Mutant IDH1 gliomas downregulate phosphocholine and phosphoethanolamine synthesis in a 2-hydroxyglutarate-dependent manner.Metabolic characterization of isocitrate dehydrogenase (IDH) mutant and IDH wildtype gliomaspheres uncovers cell type-specific vulnerabilities.Lactic Acidosis in Prostate Cancer: Consider the Warburg Effect.Immunometabolism: A novel perspective of liver cancer microenvironment and its influence on tumor progression
P2860
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P2860
IDH1 Mutation Induces Reprogramming of Pyruvate Metabolism.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
IDH1 Mutation Induces Reprogramming of Pyruvate Metabolism.
@en
type
label
IDH1 Mutation Induces Reprogramming of Pyruvate Metabolism.
@en
prefLabel
IDH1 Mutation Induces Reprogramming of Pyruvate Metabolism.
@en
P2093
P2860
P1433
P1476
IDH1 Mutation Induces Reprogramming of Pyruvate Metabolism
@en
P2093
H Artee Luchman
J Gregory Cairncross
Joanna J Phillips
Marina Radoul
Michael Blough
Pavithra Viswanath
Pia Eriksson
Russell O Pieper
Sabrina M Ronen
P2860
P304
P356
10.1158/0008-5472.CAN-15-0840
P407
P577
2015-06-04T00:00:00Z