Identification of a novel synthetic lethality of combined inhibition of hedgehog and PI3K signaling in rhabdomyosarcoma
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The hedgehog pathway in triple-negative breast cancerThe mTOR pathway in obesity driven gastrointestinal cancers: Potential targets and clinical trialsProbing for a deeper understanding of rhabdomyosarcoma: insights from complementary model systems.Combined application of arsenic trioxide and lithium chloride augments viability reduction and apoptosis induction in human rhabdomyosarcoma cell lines.Targeting Focal Adhesion Kinase Suppresses the Malignant Phenotype in Rhabdomyosarcoma CellsGenomic characterization of patient-derived xenograft models established from fine needle aspirate biopsies of a primary pancreatic ductal adenocarcinoma and from patient-matched metastatic sitesSmall GTPase Arl6 controls RH30 rhabdomyosarcoma cell growth through ciliogenesis and Hedgehog signaling.Targeting the PI3K/AKT pathway via GLI1 inhibition enhanced the drug sensitivity of acute myeloid leukemia cells.JNJ-26481585 primes rhabdomyosarcoma cells for chemotherapeutics by engaging the mitochondrial pathway of apoptosis.Suppression of GLI sensitizes medulloblastoma cells to mitochondria-mediated apoptosisBasal cell carcinoma pathogenesis and therapy involving hedgehog signaling and beyond.Efficient elimination of pancreatic cancer stem cells by hedgehog/GLI inhibitor GANT61 in combination with mTOR inhibition.Hedgehog Inhibitors in Rhabdomyosarcoma: A Comparison of Four Compounds and Responsiveness of Four Cell Lines.Generation and characterization of ErbB2-CAR-engineered cytokine-induced killer cells for the treatment of high-risk soft tissue sarcoma in children.Polymeric glabrescione B nanocapsules for passive targeting of Hedgehog-dependent tumor therapy in vitro.Critical role of mitochondria-mediated apoptosis for JNJ-26481585-induced antitumor activity in rhabdomyosarcomaDifferent Response of Mutant and Wildtype Rhabdomyosarcoma Toward SMO and PI3K InhibitorsRole of GLI Transcription Factors in Pathogenesis and Their Potential as New Therapeutic Targets
P2860
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P2860
Identification of a novel synthetic lethality of combined inhibition of hedgehog and PI3K signaling in rhabdomyosarcoma
description
2015 nî lūn-bûn
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2015年の論文
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2015年学术文章
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2015年学术文章
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2015年学术文章
@zh-hans
2015年学术文章
@zh-my
2015年学术文章
@zh-sg
2015年學術文章
@yue
2015年學術文章
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2015年學術文章
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name
Identification of a novel synt ...... signaling in rhabdomyosarcoma
@en
type
label
Identification of a novel synt ...... signaling in rhabdomyosarcoma
@en
prefLabel
Identification of a novel synt ...... signaling in rhabdomyosarcoma
@en
P2860
P356
P1433
P1476
Identification of a novel synt ...... signaling in rhabdomyosarcoma
@en
P2093
Heidi Hahn
Ulrike Graab
P2860
P304
P356
10.18632/ONCOTARGET.2726
P407
P50
P577
2015-04-01T00:00:00Z