CDK1 inhibition targets the p53-NOXA-MCL1 axis, selectively kills embryonic stem cells, and prevents teratoma formation.
about
Inhibition of MARCH5 ubiquitin ligase abrogates MCL1-dependent resistance to BH3 mimetics via NOXADinaciclib potently suppresses MCL-1 and selectively induces the cell death in human iPS cells without affecting the viability of cardiac tissue.Elimination of undifferentiated human embryonic stem cells by cardiac glycosides.Tumour resistance in induced pluripotent stem cells derived from naked mole-rats.Signaling involved in stem cell reprogramming and differentiation.Isolation, Characterization, Cryopreservation of Human Amniotic Stem Cells and Differentiation to Osteogenic and Adipogenic Cells.Single-cell analysis reveals a stem-cell program in human metastatic breast cancer cellsP53 Regulates Rapid Apoptosis in Human Pluripotent Stem Cells.Mitochondria in human pluripotent stem cell apoptosis.p53 and p73 Regulate Apoptosis but Not Cell-Cycle Progression in Mouse Embryonic Stem Cells upon DNA Damage and Differentiation.Crosstalk between stem cell and cell cycle machineries.Teratoma: from spontaneous tumors to the pluripotency/malignancy assay.DNA repair mechanisms in embryonic stem cells.Technical approaches to induce selective cell death of pluripotent stem cells.Cell cycle and pluripotency: Convergence on octamer‑binding transcription factor 4 (Review).MicroRNA-302 switch to identify and eliminate undifferentiated human pluripotent stem cells.Eliminating residual iPS cells for safety in clinical applicationNovel surface-enhanced Raman scattering-based assays for ultra-sensitive detection of human pluripotent stem cellsPreventing Pluripotent Cell Teratoma in Regenerative Medicine Applied to Hematology Disorders.Increased survival and cell cycle progression pathways are required for EWS/FLI1-induced malignant transformation.Mitochondrial dysfunction RAD51, and Ku80 proteolysis promote apoptotic effects of Dinaciclib in Bcl-xL silenced cells.Myeloid cell leukemia 1 (MCL-1), an unexpected modulator of protein kinase signaling during invasion.Pluripotent Stem Cell-Derived Cardiomyocytes as a Platform for Cell Therapy Applications: Progress and Hurdles for Clinical Translation.Comparison of Teratoma Formation between Embryonic Stem Cells and Parthenogenetic Embryonic Stem Cells by Molecular Imaging.Cycling to Meet Fate: Connecting Pluripotency to the Cell Cycle.Synthesis and pharmacological evaluation of novel epidermal growth factor receptor inhibitors against prostate tumor cells
P2860
Q28830560-23617DCF-FCF5-4B58-8B57-4C014DF56C2AQ30843418-121327E7-BB1C-4731-A0CA-E2D5CBF0BAEDQ33902853-DFB2B48B-3AFE-4AE4-8C72-05BE7BC4C246Q34046796-9B6659D0-BD88-4DAC-B660-872B576E24B3Q35998667-BA026923-14B7-46DC-B4E5-24ACA804D26CQ36081590-ECD8E776-CC7B-4ECA-A1E8-951FC8EB1683Q36288896-0E2D693F-DBEB-495C-A2DE-4D0BD538E77AQ36522722-9EA0343C-119E-404A-9237-0DADAB4C8259Q36723084-E0E692C1-0A36-4FA1-ACA6-78C3FE746346Q37510423-079B383D-DAF4-43FA-862D-8A416CBF804FQ38621243-AF55EA87-5751-4F92-BBF5-9FCC51D2037CQ38677423-DEEC4BB6-7A1F-4260-9B32-4B2A4F93FEDDQ38950973-882BC74F-031A-473A-A16D-53548F50CF31Q39155502-B7057CBE-CEF0-4342-9DDD-03AE356CCE17Q40049641-B86F56CA-CBEB-4305-9AAC-D78792BB34D9Q41050244-9E36DC3F-F6D4-4190-BF53-F91B05EEBC7EQ41440518-C6C24457-C470-4811-9271-6D1B5A927099Q41634297-EA844D0E-575B-4CDC-98EB-DB42F0B753C3Q41896979-3324A3EA-A7BA-486E-96E3-B3321F39940AQ42126638-13F63B96-6C91-47E2-B011-CAF36173A24BQ47294507-21707FB3-6D62-4CCB-904D-52E9A8F8A27EQ47373137-D6289F20-4395-4E4E-9A48-565B85050949Q52560413-F286EE35-AADD-4092-8B9D-52C0CD603806Q54961506-59E478C8-81D3-4F84-9948-0279EDA0CF9CQ55420217-66B2EC79-7158-415B-BF72-4B5D2C59D6C5Q58572503-B8136241-1694-4BA7-8552-3939E978AFF5
P2860
CDK1 inhibition targets the p53-NOXA-MCL1 axis, selectively kills embryonic stem cells, and prevents teratoma formation.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年学术文章
@wuu
2015年学术文章
@zh-cn
2015年学术文章
@zh-hans
2015年学术文章
@zh-my
2015年学术文章
@zh-sg
2015年學術文章
@yue
2015年學術文章
@zh
2015年學術文章
@zh-hant
name
CDK1 inhibition targets the p5 ...... d prevents teratoma formation.
@en
type
label
CDK1 inhibition targets the p5 ...... d prevents teratoma formation.
@en
prefLabel
CDK1 inhibition targets the p5 ...... d prevents teratoma formation.
@en
P2093
P2860
P1433
P1476
CDK1 inhibition targets the p5 ...... d prevents teratoma formation.
@en
P2093
Andrei Goga
David Pardo
Katelyn J Creasman
Kimberley J Evason
Matthias Hebrok
Noelle E Huskey
Olga Momcilovic
Robert L Judson
Scott A Oakes
Tingxia Guo
P2860
P304
P356
10.1016/J.STEMCR.2015.01.019
P577
2015-02-26T00:00:00Z