PT-1 selectively activates AMPK-γ1 complexes in mouse skeletal muscle, but activates all three γ subunit complexes in cultured human cells by inhibiting the respiratory chain.
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AMPK activators: mechanisms of action and physiological activitiesRegulation of AMP-activated protein kinase by natural and synthetic activatorsα-MSH Stimulates Glucose Uptake in Mouse Muscle and Phosphorylates Rab-GTPase-Activating Protein TBC1D1 Independently of AMPKAMP-activated protein kinase: a cellular energy sensor that comes in 12 flavoursThe AMPK activator R419 improves exercise capacity and skeletal muscle insulin sensitivity in obese mice.Skeletal muscle AMP-activated protein kinase γ1(H151R) overexpression enhances whole body energy homeostasis and insulin sensitivityTargeting AMPK: From Ancient Drugs to New Small-Molecule Activators.Differential regulation by AMP and ADP of AMPK complexes containing different γ subunit isoforms.Chronic Activation of γ2 AMPK Induces Obesity and Reduces β Cell FunctionBenzimidazole derivative small-molecule 991 enhances AMPK activity and glucose uptake induced by AICAR or contraction in skeletal muscle.Functional characterization of AMP-activated protein kinase signaling in tumorigenesis.Structure and Regulation of AMPK.Role of AMP-Activated Protein Kinase for Regulating Post-exercise Insulin Sensitivity.Mechanisms of Paradoxical Activation of AMPK by the Kinase Inhibitors SU6656 and Sorafenib.AMPK: guardian of metabolism and mitochondrial homeostasis.Novel direct AMPK activator suppresses non-small cell lung cancer through inhibition of lipid metabolism.AMPK in skeletal muscle function and metabolism.Heterotypic endosomal fusion as an initial trigger for insulin-induced glucose transporter 4 (GLUT4) translocation in skeletal muscle.Regulation of autophagy in human skeletal muscle: effects of exercise, exercise training and insulin stimulation.Lactate administration activates the ERK1/2, mTORC1, and AMPK pathways differentially according to skeletal muscle type in mouseEndothelial AMP-Activated Kinase α1 Phosphorylates eNOS on Thr495 and Decreases Endothelial NO Formation
P2860
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P2860
PT-1 selectively activates AMPK-γ1 complexes in mouse skeletal muscle, but activates all three γ subunit complexes in cultured human cells by inhibiting the respiratory chain.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年学术文章
@wuu
2015年学术文章
@zh-cn
2015年学术文章
@zh-hans
2015年学术文章
@zh-my
2015年学术文章
@zh-sg
2015年學術文章
@yue
2015年學術文章
@zh
2015年學術文章
@zh-hant
name
PT-1 selectively activates AMP ...... ibiting the respiratory chain.
@en
type
label
PT-1 selectively activates AMP ...... ibiting the respiratory chain.
@en
prefLabel
PT-1 selectively activates AMP ...... ibiting the respiratory chain.
@en
P2093
P2860
P50
P356
P1433
P1476
PT-1 selectively activates AMP ...... ibiting the respiratory chain.
@en
P2093
D Grahame Hardie
Fiona A Ross
Graeme J Gowans
P2860
P304
P356
10.1042/BJ20141142
P407
P577
2015-05-01T00:00:00Z