Momelotinib inhibits ACVR1/ALK2, decreases hepcidin production, and ameliorates anemia of chronic disease in rodents. - Wikidata - wikimedia - TriplyDB

Momelotinib inhibits ACVR1/ALK2, decreases hepcidin production, and ameliorates anemia of chronic disease in rodents.

Momelotinib inhibits ACVR1/ALK2, decreases hepcidin production, and ameliorates anemia of chronic disease in rodents.

http://www.wikidata.org/entity/Q38966659

about

JAK2 inhibitors for myeloproliferative neoplasms: what is next?Investigational Janus kinase inhibitors in development for myelofibrosis.Management of myelofibrosis: JAK inhibition and beyond.The thrombopoietin/MPL axis is activated in the Gata1low mouse model of myelofibrosis and is associated with a defective RPS14 signature.Cibinetide dampens innate immune cell functions thus ameliorating the course of experimental colitis.JAK2 aberrations in childhood B-cell precursor acute lymphoblastic leukemia.The BCR-ABL1-negative myeloproliferative neoplasms: a review of JAK inhibitors in the therapeutic armamentarium.Hepcidin: a real-time biomarker of iron need.The immunophilin FKBP12 inhibits hepcidin expression by binding the BMP type I receptor ALK2 in hepatocytes.Developmental Therapeutics in Myeloproliferative Neoplasms.JAK inhibitors for the treatment of myeloproliferative neoplasms and other disorders.Anemia in myelofibrosis-prevalence, the U2AF1 connection, new treatments.Novel Therapies for Myelofibrosis.Momelotinib therapy for myelofibrosis: a 7-year follow-up.

P2860

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P2860

Momelotinib inhibits ACVR1/ALK2, decreases hepcidin production, and ameliorates anemia of chronic disease in rodents.

http://www.wikidata.org/entity/Q38966659

description

2017 nî lūn-bûn

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2017年の論文

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2017年论文

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name

Momelotinib inhibits ACVR1/ALK ...... of chronic disease in rodents.

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Momelotinib inhibits ACVR1/ALK ...... of chronic disease in rodents.

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Momelotinib inhibits ACVR1/ALK ...... of chronic disease in rodents.

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Momelotinib inhibits ACVR1/ALK ...... of chronic disease in rodents

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David Haschka

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Egon Demetz

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Gregg Smith

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Guenter Weiss

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Igor Theurl

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J Andrew Whitney

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Malte Asshoff

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Markus Seifert

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Matthew R Warr

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Pat Maciejewski

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P2860

LEAP-1, a novel highly disulfide-bonded human peptide, exhibits antimicrobial activity

Hepcidin, a urinary antimicrobial peptide synthesized in the liver

Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization

Jak2 deficiency defines an essential developmental checkpoint in definitive hematopoiesis

A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload

Jak2 is essential for signaling through a variety of cytokine receptors

Two to tango: regulation of Mammalian iron metabolism

Iron regulation by hepcidin

Lack of the bone morphogenetic protein BMP6 induces massive iron overload

Pathways for the regulation of hepcidin expression in anemia of chronic disease and iron deficiency anemia in vivo

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1823-1830

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Christopher J. Burns

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