A computational study of the Warburg effect identifies metabolic targets inhibiting cancer migration.
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Transcriptomics resources of human tissues and organsPersonalized Cardiovascular Disease Prediction and Treatment-A Review of Existing Strategies and Novel Systems Medicine ToolsCancer Metabolism: A Modeling PerspectiveApplications of Genome-Scale Metabolic Models in Biotechnology and Systems MedicineRedox control of glutamine utilization in cancerChanging perspective on oncometabolites: from metabolic signature of cancer to tumorigenic and immunosuppressive agentsAssessment of FBA Based Gene Essentiality Analysis in Cancer with a Fast Context-Specific Network Reconstruction MethodData-Driven Metabolic Pathway Compositions Enhance Cancer Survival Prediction.Flux balance analysis predicts essential genes in clear cell renal cell carcinoma metabolism.Phenotype-based cell-specific metabolic modeling reveals metabolic liabilities of cancer.Computational strategies for a system-level understanding of metabolism.Origin of cells and network informationThe gut microbiota modulates host amino acid and glutathione metabolism in miceModeling cancer metabolism on a genome scale.Extensive weight loss reveals distinct gene expression changes in human subcutaneous and visceral adipose tissue.Mitochondrial Genetics Regulate Breast Cancer Tumorigenicity and Metastatic Potential.Fostering synergy between cell biology and systems biology.Loss of 11βHSD1 enhances glycolysis, facilitates intrahepatic metastasis, and indicates poor prognosis in hepatocellular carcinomaPyruvate dehydrogenase expression is negatively associated with cell stemness and worse clinical outcome in prostate cancers.Personal model-assisted identification of NAD+ and glutathione metabolism as intervention target in NAFLD.Deciphering Epithelial-Mesenchymal Transition Regulatory Networks in Cancer through Computational ApproachesA systems approach reveals distinct metabolic strategies among the NCI-60 cancer cell lines.Genome-scale modeling of NADPH-driven β-lapachone sensitization in head and neck squamous cell carcinoma.Metabolic profiling of triple-negative breast cancer cells reveals metabolic vulnerabilities.Robust Analysis of Fluxes in Genome-Scale Metabolic PathwaysLogical transformation of genome-scale metabolic models for gene level applications and analysis.Defining Cancer Subpopulations by Adaptive Strategies Rather Than Molecular Properties Provides Novel Insights into Intratumoral Evolution.Modeling the Genetic Regulation of Cancer Metabolism: Interplay between Glycolysis and Oxidative Phosphorylation.New Challenges to Study Heterogeneity in Cancer Redox Metabolism.Metabolic modeling of muscle metabolism identifies key reactions linked to insulin resistance phenotypes.Network analyses identify liver-specific targets for treating liver diseases.Pyruvate kinase M2 and the mitochondrial ATPase Inhibitory Factor 1 provide novel biomarkers of dermatomyositis: a metabolic link to oncogenesis.Reversal of the glycolytic phenotype of primary effusion lymphoma cells by combined targeting of cellular metabolism and PI3K/Akt/ mTOR signaling.In Silico Modeling of Liver Metabolism in a Human Disease Reveals a Key Enzyme for Histidine and Histamine Homeostasis.A metabolic core model elucidates how enhanced utilization of glucose and glutamine, with enhanced glutamine-dependent lactate production, promotes cancer cell growth: The WarburQ effect.In-silico gene essentiality analysis of polyamine biosynthesis reveals APRT as a potential target in cancer.The Emerging Facets of Non-Cancerous Warburg Effect.An integrated computational and experimental study uncovers FUT9 as a metabolic driver of colorectal cancer.Framework and resource for more than 11,000 gene-transcript-protein-reaction associations in human metabolism.NADH Shuttling Couples Cytosolic Reductive Carboxylation of Glutamine with Glycolysis in Cells with Mitochondrial Dysfunction.
P2860
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P2860
A computational study of the Warburg effect identifies metabolic targets inhibiting cancer migration.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年学术文章
@wuu
2014年学术文章
@zh-cn
2014年学术文章
@zh-hans
2014年学术文章
@zh-my
2014年学术文章
@zh-sg
2014年學術文章
@yue
2014年學術文章
@zh
2014年學術文章
@zh-hant
name
A computational study of the W ...... s inhibiting cancer migration.
@en
type
label
A computational study of the W ...... s inhibiting cancer migration.
@en
prefLabel
A computational study of the W ...... s inhibiting cancer migration.
@en
P2093
P2860
P50
P356
P1476
A computational study of the W ...... s inhibiting cancer migration.
@en
P2093
Bob van de Water
Franziska Baenke
Keren Yizhak
Sylvia E Le Dévédec
Vasiliki Maria Rogkoti
Vincent C de Boer
P2860
P356
10.15252/MSB.20134993
P577
2014-08-01T00:00:00Z