about
Automated whole animal bio-imaging assay for human cancer disseminationAutomated analysis of NF-κB nuclear translocation kinetics in high-throughput screeningIdentification of cisplatin-regulated metabolic pathways in pluripotent stem cellsProteomic analysis of alternative protein tyrosine phosphorylation in 1,2-dichlorovinyl-cysteine-induced cytotoxicity in primary cultured rat renal proximal tubular cellsExtracellular signal-regulated kinase activation during renal ischemia/reperfusion mediates focal adhesion dissolution and renal injuryFocal adhesion kinase and protein kinase B cooperate to suppress doxorubicin-induced apoptosis of breast tumor cellsStem cell-derived models to improve mechanistic understanding and prediction of human drug-induced liver injuryAnnexin A2 phosphorylation mediates cell scattering and branching morphogenesis via cofilin Activation.Two-photon intravital multicolor imaging combined with inducible gene expression to distinguish metastatic behavior of breast cancer cells in vivo.Pathways of proximal tubular cell death in bismuth nephrotoxicity.Epidermal growth factor receptor signalling in human breast cancer cells operates parallel to estrogen receptor α signalling and results in tamoxifen insensitive proliferationAnnexin A1 regulates TGF-beta signaling and promotes metastasis formation of basal-like breast cancer cells.Diclofenac inhibits tumor necrosis factor-α-induced nuclear factor-κB activation causing synergistic hepatocyte apoptosis.Functional screening with a live cell imaging-based random cell migration assay.Ultra high content image analysis and phenotype profiling of 3D cultured micro-tissues.Phenotype-based cell-specific metabolic modeling reveals metabolic liabilities of cancer.Silencing of doublecortin-like (DCL) results in decreased mitochondrial activity and delayed neuroblastoma tumor growth.Mammary gland tumor promotion by chronic administration of IGF1 and the insulin analogue AspB10 in the p53R270H/⁺WAPCre mouse modelTumor cell migration screen identifies SRPK1 as breast cancer metastasis determinant.Toxicogenomics directory of chemically exposed human hepatocytes.Elevated insulin-like growth factor 1 receptor signaling induces antiestrogen resistance through the MAPK/ERK and PI3K/Akt signaling routes.Focal adhesion kinase signaling mediates acute renal injury induced by ischemia/reperfusion.Annexin A1 expression in a pooled breast cancer series: association with tumor subtypes and prognosis.Alternative signaling network activation through different insulin receptor family members caused by pro-mitogenic antidiabetic insulin analogues in human mammary epithelial cellsTreatment with insulin (analogues) and breast cancer risk in diabetics; a systematic review and meta-analysis of in vitro, animal and human evidence.cAMP signalling protects proximal tubular epithelial cells from cisplatin-induced apoptosis via activation of EpacTumor-induced remote ECM network orientation steers angiogenesis.Elucidation of Signaling Pathways from Large-Scale Phosphoproteomic Data Using Protein Interaction Networks.Cellular stress responses and molecular mechanisms of nephrotoxicity.Phospho-proteomic analysis of cellular signaling.Focal adhesion kinase: a potential target in cancer therapy.An improved model to study tumor cell autonomous metastasis programs using MTLn3 cells and the Rag2(-/-) gammac (-/-) mouse.Insulin-like growth factor 1 receptor activation promotes mammary gland tumor development by increasing glycolysis and promoting biomass production.Cellular-signaling pathways unveil the carcinogenic potential of chemicals.Unraveling DNA damage response-signaling networks through systems approaches.Quantitative high content imaging of cellular adaptive stress response pathways in toxicity for chemical safety assessment.Current approaches and future role of high content imaging in safety sciences and drug discovery.A portrait of cisplatin-induced transcriptional changes in mouse embryonic stem cells reveals a dominant p53-like response.Stem cell-derived systems in toxicology assessment.The adhesion G protein-coupled receptor G2 (ADGRG2/GPR64) constitutively activates SRE and NFκB and is involved in cell adhesion and migration.
P50
Q27309083-7B98EEE1-60B2-4EB1-B779-23DBA5D2DE97Q28484608-876AA0DF-32C7-4115-B873-D66365209092Q28534469-D3B45076-4E2F-48AB-99AF-612B1A50EB96Q28573857-FA8F63A3-FE82-41B2-9BA3-F10B02B90DB9Q28577682-F2328093-17F7-4C61-BA46-ECB332C31788Q28578168-6C66BED9-1034-4EAB-9676-F82C4BD8E835Q28818235-2FAD8668-D329-440E-B167-B1E953E652ECQ30481149-DD38BEB5-1ED9-47E7-84EC-D8E4A435B390Q30497933-C0189A40-C40D-4BFC-A403-4946A7D9E6F8Q33183626-A6E92CED-A31D-4DE0-A87D-D1E3BFBC9E46Q33612070-743735E9-893A-4F2F-9358-8F48891ECBBCQ33779042-CA391242-F669-4BF1-AEBA-AF20996E9724Q33854289-98DD6E69-563E-442B-AB05-638D2ABF485AQ33958512-1C3FAE6E-011E-4364-A78F-C5EBA05682D8Q34302129-8928C0E1-86EC-4B04-B81A-FA1D09ED7516Q34545824-781E67E7-E5C2-4593-BA79-FADB608D6C8FQ35005945-DFB42FBE-2643-4554-BC5B-C26CCBB89C82Q35147769-959E5622-35DD-4911-97B8-E41F6F3587C6Q35408783-FDADCD51-1509-4916-8C2B-DFA1D3603397Q35423042-DF7E1688-B066-4FF7-9F91-395D47D8AD4EQ35558050-BB711B15-F106-4262-8EA2-8880445EF0CCQ35679406-83DDAC57-026D-4F94-95C9-FC2DDB41912CQ35681656-E585958B-E01F-4A37-B582-9F458D0838A1Q35863765-46B73A63-10C5-4FE5-8E66-C679924B12B6Q35937961-A1B66317-5AE1-41B1-A6F0-E0B05132CD3CQ35940362-48A88DAA-A28D-4338-9E42-BB0FC62C7410Q35941690-134A30BC-F693-4D91-9B11-93DA8791FE05Q36232229-6CC363BB-E872-4EA0-8526-D27333C40D02Q36344421-8798B816-7F3D-4695-A6F7-6468EC2B1E8AQ36494339-474ADD78-0E19-42D2-8C23-ADF650C4E18BQ36602100-CDB2C231-97D7-4A3D-A79F-B853229A0AF1Q37418688-C01DB228-FB1D-4070-AA0E-95319585B300Q37630922-7A5295CA-7ED7-42DD-8648-2BFD2DDF7994Q38075860-EC70BDBB-C048-408F-8F6F-79DC2EDE6557Q38128769-9D476984-923C-4E23-AA8F-D5CFD18CB037Q38180817-20949E23-1E52-4B15-BC83-5841CBF9F7F1Q38229861-F472E1A2-FC5D-4D44-A950-A66110E9F349Q38304258-C679A39C-52E3-46CD-A615-4D46E2A4421DQ38353008-E254F677-88CE-4419-8627-B9ABCC483346Q38839503-0F92335F-16A5-414B-9DD0-B691CF37B82C
P50
description
academisch docent
@nl
name
Bob van de Water
@ast
Bob van de Water
@en
Bob van de Water
@es
Bob van de Water
@fr
Bob van de Water
@nl
type
label
Bob van de Water
@ast
Bob van de Water
@en
Bob van de Water
@es
Bob van de Water
@fr
Bob van de Water
@nl
altLabel
B. van de Water
@nl
prefLabel
Bob van de Water
@ast
Bob van de Water
@en
Bob van de Water
@es
Bob van de Water
@fr
Bob van de Water
@nl