A functional cancer genomics screen identifies a druggable synthetic lethal interaction between MSH3 and PRKDC.
about
Targeting ATM-deficient CLL through interference with DNA repair pathwaysBeyond DNA repair: DNA-PK function in cancerEMAST is a Form of Microsatellite Instability That is Initiated by Inflammation and Modulates Colorectal Cancer ProgressionGenetics and Genetic Biomarkers in Sporadic Colorectal CancerThe PIN domain of EXO1 recognizes poly(ADP-ribose) in DNA damage response.Novel kinase fusion transcripts found in endometrial cancerTowards a compendium of essential genes - From model organisms to synthetic lethality in cancer cells.HEREDITARY, SPORADIC AND METASTATIC COLORECTAL CANCER ARE COMMONLY DRIVEN BY SPECIFIC SPECTRUMS OF DEFECTIVE DNA MISMATCH REPAIR COMPONENTS.Targeting hyperactivated DNA-PKcs by KU0060648 inhibits glioma progression and enhances temozolomide therapy via suppression of AKT signaling.Loss of MLH1 sensitizes colon cancer cells to DNA-PKcs inhibitor KU60648.Driver gene classification reveals a substantial overrepresentation of tumor suppressors among very large chromatin-regulating proteins.Two mouse models reveal an actionable PARP1 dependence in aggressive chronic lymphocytic leukemiaFrom breaking bad to worse: exploiting homologous DNA repair deficiency in cancer.Targeting a non-oncogene addiction to the ATR/CHK1 axis for the treatment of small cell lung cancer.Directing the use of DDR kinase inhibitors in cancer treatment.Inflammation-associated microsatellite alterations: Mechanisms and significance in the prognosis of patients with colorectal cancer.Clinically actionable mutation profiles in patients with cancer identified by whole-genome sequencing.Microsatellite Instability Pathway and EMAST in Colorectal Cancer.
P2860
Q26822592-15690B5A-5427-443D-8274-927B83C89FEEQ26827232-A799DB27-B92A-4EB7-810F-0BA35C3B5EA7Q26995653-2460B619-CCEC-4E79-843A-E75E7FF447EDQ28084346-1FD6050D-BDF3-4FD8-92C9-1A0158F1A32EQ36370917-4A6F5819-5FBC-46A6-9E0F-1DC303301036Q36393068-62A65A62-3599-4C2F-B1FF-B94046776568Q36762503-8AD9664B-3FA6-4BD3-AE02-508E7129BC47Q37563827-B2CE07CA-83C5-4BDD-9C4C-5F4801857AF9Q37688272-1BCCD9CC-9D12-46FE-91F7-09267F93F688Q38715402-12EC15B3-0B14-4939-ABFD-2B7DBA9CEBBBQ39069342-C753DD98-4A6B-4BEF-B0CD-473FB303C7EAQ41158692-94F31A49-0AC9-4814-B4C2-4EC57DDA1597Q43215257-311114CC-F54C-4996-98A1-2D4D4B53AE00Q47120183-D4A02A68-E159-4776-979F-1D91E15B0E4EQ47687840-666337CC-744E-4EF0-85A6-25F0A7444524Q49452061-B2140973-AB65-480C-B185-4543FB4973ABQ52611832-BA0EF206-1664-4978-9501-28F80BB97B23Q53698643-97027BE0-03EA-4D12-BDCA-9CC619B1D79E
P2860
A functional cancer genomics screen identifies a druggable synthetic lethal interaction between MSH3 and PRKDC.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
2014年论文
@zh
2014年论文
@zh-cn
name
A functional cancer genomics s ...... action between MSH3 and PRKDC.
@en
A functional cancer genomics s ...... action between MSH3 and PRKDC.
@nl
type
label
A functional cancer genomics s ...... action between MSH3 and PRKDC.
@en
A functional cancer genomics s ...... action between MSH3 and PRKDC.
@nl
prefLabel
A functional cancer genomics s ...... action between MSH3 and PRKDC.
@en
A functional cancer genomics s ...... action between MSH3 and PRKDC.
@nl
P2093
P1433
P1476
A functional cancer genomics s ...... raction between MSH3 and PRKDC
@en
P2093
Felix Dietlein
Gero Knittel
H Christian Reinhardt
Johanna van Oers
Laura Ivan
Lisa Thelen
Mladen Jokic
Ron D Jachimowicz
Uschi Leeser
Winfried Edelmann
P304
P356
10.1158/2159-8290.CD-13-0907
P577
2014-02-20T00:00:00Z