A pan-cancer analysis of transcriptome changes associated with somatic mutations in U2AF1 reveals commonly altered splicing events - Wikidata - wikimedia - TriplyDB

A pan-cancer analysis of transcriptome changes associated with somatic mutations in U2AF1 reveals commonly altered splicing events

A pan-cancer analysis of transcriptome changes associated with somatic mutations in U2AF1 reveals commonly altered splicing events

http://www.wikidata.org/entity/Q39027040

about

Spliceosomal gene mutations in myelodysplasia: molecular links to clonal abnormalities of hematopoiesis Defective control of pre-messenger RNA splicing in human disease Comprehensive molecular profiling of lung adenocarcinoma.Large-scale analysis of genome and transcriptome alterations in multiple tumors unveils novel cancer-relevant splicing networks Elucidating Genomic Characteristics of Lung Cancer Progression from In Situ to Invasive Adenocarcinoma Allelic imbalance of somatic mutations in cancer genomes and transcriptomes.The U2AF1S34F mutation induces lineage-specific splicing alterations in myelodysplastic syndromes.Transcriptome instability as a molecular pan-cancer characteristic of carcinomas Kinetic competition during the transcription cycle results in stochastic RNA processing.Mechanisms and Regulation of Alternative Pre-mRNA Splicing RNA-binding proteins in pluripotency, differentiation, and reprogramming.Cancer systems biology of TCGA SKCM: efficient detection of genomic drivers in melanoma.The genetics of splicing in neuroblastoma.U2AF1 mutations alter sequence specificity of pre-mRNA binding and splicing SRSF2 Mutations Contribute to Myelodysplasia by Mutant-Specific Effects on Exon Recognition.Mutant U2AF1 Expression Alters Hematopoiesis and Pre-mRNA Splicing In Vivo.The Activation-Induced Assembly of an RNA/Protein Interactome Centered on the Splicing Factor U2AF2 Regulates Gene Expression in Human CD4 T Cells Mutational landscape of mucinous ovarian carcinoma and its neoplastic precursors.Wild-Type U2AF1 Antagonizes the Splicing Program Characteristic of U2AF1-Mutant Tumors and Is Required for Cell Survival.Differential expression of alternatively spliced transcripts related to energy metabolism in colorectal cancer.Integrative DNA methylome analysis of pan-cancer biomarkers in cancer discordant monozygotic twin-pairs RNA splicing factors as oncoproteins and tumour suppressors.Mutant U2AF1-expressing cells are sensitive to pharmacological modulation of the spliceosome.Molecular pathogenesis of atypical CML, CMML and MDS/MPN-unclassifiable.Splice factor mutations and alternative splicing as drivers of hematopoietic malignancy.Next-generation sequencing-based panel testing for myeloid neoplasms.Transcriptomic Characterization of SF3B1 Mutation Reveals Its Pleiotropic Effects in Chronic Lymphocytic Leukemia.Alternative splicing: the pledge, the turn, and the prestige : The key role of alternative splicing in human biological systems.U2AF35(S34F) Promotes Transformation by Directing Aberrant ATG7 Pre-mRNA 3' End Formation.Splicing-factor alterations in cancers.Splicing factor gene mutations in hematologic malignancies.Splicing Factor Mutations in Myelodysplasias: Insights from Spliceosome Structures.RNA processing as an alternative route to attack glioblastoma.Widespread intron retention diversifies most cancer transcriptomes.Nanopore long-read RNAseq reveals widespread transcriptional variation among the surface receptors of individual B cells.Integrative genome-wide analysis of the determinants of RNA splicing in kidney renal clear cell carcinoma.U2AF1 mutations alter splice site recognition in hematological malignancies.A large-scale analysis of alternative splicing reveals a key role of QKI in lung cancer.The role of alternative splicing in cancer.A novel 3' splice site recognition by the two zinc fingers in the U2AF small subunit.

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P2860

A pan-cancer analysis of transcriptome changes associated with somatic mutations in U2AF1 reveals commonly altered splicing events

http://www.wikidata.org/entity/Q39027040

description

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name

A pan-cancer analysis of trans ...... mmonly altered splicing events

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A pan-cancer analysis of trans ...... monly altered splicing events.

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A pan-cancer analysis of trans ...... mmonly altered splicing events

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A pan-cancer analysis of trans ...... mmonly altered splicing events

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Angela N Brooks

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Chandra Sekhar Pedamallu

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David S DeLuca

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Luc de Waal

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Michael S Lawrence

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Peter S Choi

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Tanaz Sharifnia

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P2860

A novel peptide recognition mode revealed by the X-ray structure of a core U2AF35/U2AF65 heterodimer

Identification, purification, and biochemical characterization of U2 small nuclear ribonucleoprotein auxiliary factor

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.

Sequence logos: a new way to display consensus sequences

The Cancer Genome Atlas Pan-Cancer analysis project

GENCODE: the reference human genome annotation for The ENCODE Project

Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

A census of human cancer genes

TopHat: discovering splice junctions with RNA-Seq

WebLogo: A Sequence Logo Generator

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Marcin Imielinski

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Juliann Chmielecki

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