Secondary consequences of beta cell inexcitability: identification and prevention in a murine model of K(ATP)-induced neonatal diabetes mellitus.
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Neonatal diabetes: an expanding list of genes allows for improved diagnosis and treatmentPhase transitions in the multi-cellular regulatory behavior of pancreatic islet excitabilityNeonatal diabetes mellitus: a model for personalized medicineReversible changes in pancreatic islet structure and function produced by elevated blood glucose.Tamoxifen-Induced Cre-loxP Recombination Is Prolonged in Pancreatic Islets of Adult MiceGlucose stimulation of hypothalamic MCH neurons involves K(ATP) channels, is modulated by UCP2, and regulates peripheral glucose homeostasis.Modeling K,ATP--dependent excitability in pancreatic islets.Peroxisomal lipid synthesis regulates inflammation by sustaining neutrophil membrane phospholipid composition and viability.Muscle KATP channels: recent insights to energy sensing and myoprotectionFatty acid synthase modulates homeostatic responses to myocardial stress.Acute sulfonylurea therapy at disease onset can cause permanent remission of KATP-induced diabetes.Successful sulfonylurea treatment of an insulin-naïve neonate with diabetes mellitus due to a KCNJ11 mutationHyperinsulinism and diabetes: genetic dissection of beta cell metabolism-excitation coupling in miceDecreases in Gap Junction Coupling Recovers Ca2+ and Insulin Secretion in Neonatal Diabetes Mellitus, Dependent on Beta Cell Heterogeneity and NoisePERK is required in the adult pancreas and is essential for maintenance of glucose homeostasis.Diabetes induced by gain-of-function mutations in the Kir6.1 subunit of the KATP channel.Molecular biology of K(ATP) channels and implications for health and disease.Decreasing cx36 gap junction coupling compensates for overactive KATP channels to restore insulin secretion and prevent hyperglycemia in a mouse model of neonatal diabetes.The role of the KATP channel in glucose homeostasis in health and disease: more than meets the islet.Use of mouse models in studying type 2 diabetes mellitus.Current understanding of K ATP channels in neonatal diseases: focus on insulin secretion disorders.The diabetic β-cell: hyperstimulated vs. hyperexcited.Neonatal diabetes caused by activating mutations in the sulphonylurea receptorK(ATP) channels and islet hormone secretion: new insights and controversies.Sulfonylureas: a new look at old therapy.Intermittent Fasting Preserves Beta-Cell Mass in Obesity-induced Diabetes via the Autophagy-Lysosome Pathway.Glibenclamide treatment blocks metabolic dysfunctions and improves vagal activity in monosodium glutamate-obese male rats.Pancreatic β-cell identity in diabetes.Sulfonylurea challenge test in subjects diagnosed with type 1 diabetes mellitus.Neonatal Diabetes and the KATP Channel: From Mutation to Therapy.All mixed up: defining roles for β-cell subtypes in mature islets.Promoter DNA methylation regulates murine SUR1 (Abcc8) and SUR2 (Abcc9) expression in HL-1 cardiomyocytes.Interaction between mutations in the slide helix of Kir6.2 associated with neonatal diabetes and neurological symptoms.Defects in beta cell Ca²+ signalling, glucose metabolism and insulin secretion in a murine model of K(ATP) channel-induced neonatal diabetes mellitusPancreatic β cell dedifferentiation in diabetes and redifferentiation following insulin therapy.Fatty acid synthase modulates intestinal barrier function through palmitoylation of mucin 2.ATP and sulfonylurea linkage in the K(ATP) channel solves a diabetes puzzlerInferring gene-to-phenotype and gene-to-disease relationships at Mouse Genome Informatics: challenges and solutions.K(ATP)-channel-dependent regulation of catecholaminergic neurons controls BAT sympathetic nerve activity and energy homeostasis.Preservation of Reduced Numbers of Insulin-Positive Cells in Sulfonylurea-Unresponsive KCNJ11-Related Diabetes.
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P2860
Secondary consequences of beta cell inexcitability: identification and prevention in a murine model of K(ATP)-induced neonatal diabetes mellitus.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
Secondary consequences of beta ...... vention in a murine model of K
@nl
Secondary consequences of beta ...... ed neonatal diabetes mellitus.
@en
type
label
Secondary consequences of beta ...... vention in a murine model of K
@nl
Secondary consequences of beta ...... ed neonatal diabetes mellitus.
@en
prefLabel
Secondary consequences of beta ...... vention in a murine model of K
@nl
Secondary consequences of beta ...... ed neonatal diabetes mellitus.
@en
P2093
P2860
P1433
P1476
Secondary consequences of beta ...... ed neonatal diabetes mellitus.
@en
P2093
Ailing Tong
Alexis Scott
Andre Kleinridders
Colin G Nichols
Eva Rother
F Thomas Wunderlich
Joseph C Koster
Maria Sara Remedi
P2860
P304
P356
10.1016/J.CMET.2008.12.005
P577
2009-02-01T00:00:00Z