The PI3-kinase isoform p110δ is essential for cell transformation induced by the D816V mutant of c-Kit in a lipid-kinase-independent manner.
about
Germline mutations of KIT in gastrointestinal stromal tumor (GIST) and mastocytosisSOCS6 is a selective suppressor of receptor tyrosine kinase signaling.Aberrant activation of the PI3K/mTOR pathway promotes resistance to sorafenib in AML.FYN expression potentiates FLT3-ITD induced STAT5 signaling in acute myeloid leukemia.PI3 kinase is indispensable for oncogenic transformation by the V560D mutant of c-Kit in a kinase-independent manner.XK-related protein 5 (XKR5) is a novel negative regulator of KIT/D816V-mediated transformation.
P2860
The PI3-kinase isoform p110δ is essential for cell transformation induced by the D816V mutant of c-Kit in a lipid-kinase-independent manner.
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2013 nî lūn-bûn
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2013年の論文
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2013年論文
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name
The PI3-kinase isoform p110δ i ...... pid-kinase-independent manner.
@en
The PI3-kinase isoform p110δ i ...... pid-kinase-independent manner.
@nl
type
label
The PI3-kinase isoform p110δ i ...... pid-kinase-independent manner.
@en
The PI3-kinase isoform p110δ i ...... pid-kinase-independent manner.
@nl
prefLabel
The PI3-kinase isoform p110δ i ...... pid-kinase-independent manner.
@en
The PI3-kinase isoform p110δ i ...... pid-kinase-independent manner.
@nl
P2093
P2860
P50
P356
P1433
P1476
The PI3-kinase isoform p110δ i ...... ipid-kinase-independent manner
@en
P2093
P2860
P2888
P304
P356
10.1038/ONC.2013.479
P407
P577
2013-11-11T00:00:00Z