Inhibition of the p110α isoform of PI 3-kinase stimulates nonfunctional tumor angiogenesis.
about
Stability and function of adult vasculature is sustained by Akt/Jagged1 signalling axis in endothelium.Inactivation of PI(3)K p110δ breaks regulatory T-cell-mediated immune tolerance to cancerPI3K at the crossroads of tumor angiogenesis signaling pathwaysTargeting PI3K in cancer: impact on tumor cells, their protective stroma, angiogenesis and immunotherapyPTEN mediates Notch-dependent stalk cell arrest in angiogenesisCorrelation of extended RAS and PIK3CA gene mutation status with outcomes from the phase III AGITG MAX STUDY involving capecitabine alone or in combination with bevacizumab plus or minus mitomycin C in advanced colorectal cancerStructure, function and inhibition of the phosphoinositide 3-kinase p110α enzyme.RAS interaction with PI3K p110α is required for tumor-induced angiogenesis.Therapeutic Benefit of Selective Inhibition of p110α PI3-Kinase in Pancreatic Neuroendocrine TumorsSomatic activating mutations in Pik3ca cause sporadic venous malformations in mice and humans.Cellular context-mediated Akt dynamics regulates MAP kinase signaling thresholds during angiogenesis.Thymosin-β4-mediated therapeutic neovascularization: role of the PI3K/AKT pathway.Raddeanin A suppresses breast cancer-associated osteolysis through inhibiting osteoclasts and breast cancer cells.The impact of PI3K inhibitors on breast cancer cell and its tumor microenvironment.
P2860
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P2860
Inhibition of the p110α isoform of PI 3-kinase stimulates nonfunctional tumor angiogenesis.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Inhibition of the p110α isofor ...... functional tumor angiogenesis.
@en
Inhibition of the p110α isofor ...... functional tumor angiogenesis.
@nl
type
label
Inhibition of the p110α isofor ...... functional tumor angiogenesis.
@en
Inhibition of the p110α isofor ...... functional tumor angiogenesis.
@nl
prefLabel
Inhibition of the p110α isofor ...... functional tumor angiogenesis.
@en
Inhibition of the p110α isofor ...... functional tumor angiogenesis.
@nl
P2093
P2860
P50
P356
P1476
Inhibition of the p110α isofor ...... functional tumor angiogenesis.
@en
P2093
Adriana Soler
Ana Angulo
Bart Vanhaesebroeck
Francesc Viñals
Helena Serra
Lori S Friedman
Wayne Pearce
P2860
P304
P356
10.1084/JEM.20121571
P407
P577
2013-09-16T00:00:00Z