Uhrf1-dependent H3K23 ubiquitylation couples maintenance DNA methylation and replication. - Wikidata - wikimedia - TriplyDB

Uhrf1-dependent H3K23 ubiquitylation couples maintenance DNA methylation and replication.

Uhrf1-dependent H3K23 ubiquitylation couples maintenance DNA methylation and replication.

http://www.wikidata.org/entity/Q39098794

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DUBbing Cancer: Deubiquitylating Enzymes Involved in Epigenetics, DNA Damage and the Cell Cycle As Therapeutic Targets Functions of Ubiquitin and SUMO in DNA Replication and Replication Stress Mechanisms of interstrand DNA crosslink repair and human disorders DNA methylation pathways and their crosstalk with histone methylation DNA modifications: function and applications in normal and disease States Regulation of Unperturbed DNA Replication by Ubiquitylation Mammalian epigenetic mechanisms Signalling pathways in UHRF1-dependent regulation of tumor suppressor genes in cancer Conserved linker regions and their regulation determine multiple chromatin-binding modes of UHRF1 MBD4 interacts with and recruits USP7 to heterochromatic foci The LMO2 oncogene regulates DNA replication in hematopoietic cells Hemi-methylated DNA regulates DNA methylation inheritance through allosteric activation of H3 ubiquitylation by UHRF1 Mutations in the Chromatin Regulator Gene BRPF1 Cause Syndromic Intellectual Disability and Deficient Histone Acetylation Arabidopsis VIM proteins regulate epigenetic silencing by modulating DNA methylation and histone modification in cooperation with MET1.Poly(ADP-ribose) polymerase 1 (PARP1) associates with E3 ubiquitin-protein ligase UHRF1 and modulates UHRF1 biological functions Lsh regulates LTR retrotransposon repression independently of Dnmt3b function.UHRF1 is required for basal stem cell proliferation in response to airway injury.Functional dissection of the role of UHRF1 in the regulation of retinoblastoma methylome.VIM proteins regulate transcription exclusively through the MET1 cytosine methylation pathway Generation of nonhydrolyzable ubiquitin-histone mimics Topoisomerase II regulates the maintenance of DNA methylation.DNA hypomethylation induces a DNA replication-associated cell cycle arrest to block hepatic outgrowth in uhrf1 mutant zebrafish embryos Understanding the relationship between DNA methylation and histone lysine methylation.Epigenetic control of intestinal barrier function and inflammation in zebrafish.The epigenetic regulator Uhrf1 facilitates the proliferation and maturation of colonic regulatory T cells.H3K9 methyltransferase G9a negatively regulates UHRF1 transcription during leukemia cell differentiation Crystal Structure of Human DNA Methyltransferase 1 An Allosteric Interaction Links USP7 to Deubiquitination and Chromatin Targeting of UHRF1.A cell cycle-dependent BRCA1-UHRF1 cascade regulates DNA double-strand break repair pathway choice Protein monoubiquitylation: targets and diverse functions UHRF1 contributes to DNA damage repair as a lesion recognition factor and nuclease scaffold.H3K23me2 is a new heterochromatic mark in Caenorhabditis elegans.Hemi-methylated DNA opens a closed conformation of UHRF1 to facilitate its histone recognition.Negative regulation of DNMT3A de novo DNA methylation by frequently overexpressed UHRF family proteins as a mechanism for widespread DNA hypomethylation in cancer.Zinc Finger Protein 618 Regulates the Function of UHRF2 (Ubiquitin-like with PHD and Ring Finger Domains 2) as a Specific 5-Hydroxymethylcytosine Reader UHRF1 regulates global DNA hypomethylation and is associated with poor prognosis in esophageal squamous cell carcinoma.UHRF1 overexpression drives DNA hypomethylation and hepatocellular carcinoma Regulation of stem cell function by protein ubiquitylation Heritable Gene Regulation in the CD4:CD8 T Cell Lineage Choice.Regulation of protein stability of DNA methyltransferase 1 by post-translational modifications

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P2860

Uhrf1-dependent H3K23 ubiquitylation couples maintenance DNA methylation and replication.

http://www.wikidata.org/entity/Q39098794

description

2013 nî lūn-bûn

@nan

2013年の論文

@ja

2013年論文

@yue

2013年論文

@zh-hant

2013年論文

@zh-hk

2013年論文

@zh-mo

2013年論文

@zh-tw

2013年论文

@wuu

2013年论文

@zh

2013年论文

@zh-cn

name

Uhrf1-dependent H3K23 ubiquitylation couples maintenance DNA methylation and replication.

@en

Uhrf1-dependent H3K23 ubiquitylation couples maintenance DNA methylation and replication.

@nl

type

label

Uhrf1-dependent H3K23 ubiquitylation couples maintenance DNA methylation and replication.

@en

Uhrf1-dependent H3K23 ubiquitylation couples maintenance DNA methylation and replication.

@nl

prefLabel

Uhrf1-dependent H3K23 ubiquitylation couples maintenance DNA methylation and replication.

@en

Uhrf1-dependent H3K23 ubiquitylation couples maintenance DNA methylation and replication.

@nl

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P1476

Uhrf1-dependent H3K23 ubiquitylation couples maintenance DNA methylation and replication.

@en

P2093

Fuyuki Ishikawa

http://www.w3.org/2001/XMLSchema#string

Jafar Sharif

http://www.w3.org/2001/XMLSchema#string

Keiko Nakanishi

http://www.w3.org/2001/XMLSchema#string

Kyohei Arita

http://www.w3.org/2001/XMLSchema#string

Luna Yamaguchi

http://www.w3.org/2001/XMLSchema#string

Makoto Nakanishi

http://www.w3.org/2001/XMLSchema#string

Shintaro Shimamura

http://www.w3.org/2001/XMLSchema#string

Takeshi Kawamura

http://www.w3.org/2001/XMLSchema#string

Tatsuhiko Kodama

http://www.w3.org/2001/XMLSchema#string

Yoshikazu Johmura

http://www.w3.org/2001/XMLSchema#string

P2860

DNA methylation patterns and epigenetic memory

The interaction of the SRA domain of ICBP90 with a novel domain of DNMT1 is involved in the regulation of VEGF gene expression

ICBP90, a novel methyl K9 H3 binding protein linking protein ubiquitination with heterochromatin formation

Recognition of multivalent histone states associated with heterochromatin by UHRF1 protein

The USP7/Dnmt1 complex stimulates the DNA methylation activity of Dnmt1 and regulates the stability of UHRF1

PHD finger recognition of unmodified histone H3R2 links UHRF1 to regulation of euchromatic gene expression

MCM-BP regulates unloading of the MCM2-7 helicase in late S phase

UHRF1 plays a role in maintaining DNA methylation in mammalian cells

Critical role of the ubiquitin ligase activity of UHRF1, a nuclear RING finger protein, in tumor cell growth.

Np95 is a histone-binding protein endowed with ubiquitin ligase activity

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249-253

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scholarly article

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10.1038/NATURE12488

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P433

7470

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P478

502

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Haruhiko Koseki

Atsuya Nishiyama

P577

2013-09-08T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

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1010491626

http://www.w3.org/2001/XMLSchema#string

P698

24013172

http://www.w3.org/2001/XMLSchema#string

P921

DNA methylation