FTY720 induces apoptosis of chronic myelogenous leukemia cells via dual activation of BIM and BID and overcomes various types of resistance to tyrosine kinase inhibitors.
about
The broken "Off" switch in cancer signaling: PP2A as a regulator of tumorigenesis, drug resistance, and immune surveillanceThe emerging role of FTY720 (Fingolimod) in cancer treatmentThe non-genomic loss of function of tumor suppressors: an essential role in the pathogenesis of chronic myeloid leukemia chronic phaseRegulation of Bim in Health and DiseaseAssociation of BID SNPs (rs8190315 and rs2072392) and clinical features of benign prostate hyperplasia in Korean populationMechanisms of resistance to EGFR tyrosine kinase inhibitors.Aberrant expression of the S1P regulating enzymes, SPHK1 and SGPL1, contributes to a migratory phenotype in OSCC mediated through S1PR2.Phosphorylation of a constrained azacyclic FTY720 analog enhances anti-leukemic activity without inducing S1P receptor activation.Non-immunosuppressive triazole-based small molecule induces anticancer activity against human hormone-refractory prostate cancers: the role in inhibition of PI3K/AKT/mTOR and c-Myc signaling pathwaysRole of Sphingolipids and Metabolizing Enzymes in Hematological Malignancies.The antineoplastic properties of FTY720: evidence for the repurposing of fingolimod.The impact of phosphatases on proliferative and survival signaling in cancer.
P2860
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P2860
FTY720 induces apoptosis of chronic myelogenous leukemia cells via dual activation of BIM and BID and overcomes various types of resistance to tyrosine kinase inhibitors.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
FTY720 induces apoptosis of ch ...... to tyrosine kinase inhibitors.
@en
FTY720 induces apoptosis of ch ...... to tyrosine kinase inhibitors.
@nl
type
label
FTY720 induces apoptosis of ch ...... to tyrosine kinase inhibitors.
@en
FTY720 induces apoptosis of ch ...... to tyrosine kinase inhibitors.
@nl
prefLabel
FTY720 induces apoptosis of ch ...... to tyrosine kinase inhibitors.
@en
FTY720 induces apoptosis of ch ...... to tyrosine kinase inhibitors.
@nl
P2093
P2860
P1433
P1476
FTY720 induces apoptosis of ch ...... to tyrosine kinase inhibitors.
@en
P2093
Hisao Nagoshi
Junya Kuroda
Masafumi Taniwaki
Miki Kiyota
Mio Yamamoto-Sugitani
Nana Sasaki
Natsumi Sakamoto
Ryuko Nakayama
Shigeo Horiike
Shinsuke Mizutani
P2860
P2888
P304
P356
10.1007/S10495-013-0882-Y
P577
2013-11-01T00:00:00Z