Alterations of the PPP2R1B gene located at 11q23 in human colorectal cancers
about
The tumor suppressor PP2A Abeta regulates the RalA GTPaseIdentification of PP2A complexes and pathways involved in cell transformationPP4R4/KIAA1622 forms a novel stable cytosolic complex with phosphoprotein phosphatase 4Characterization of the Aalpha and Abeta subunit isoforms of protein phosphatase 2A: differences in expression, subunit interaction, and evolutionStructural Basis of PP2A Inhibition by Small t AntigenPP2A: The Wolf in Sheep's Clothing?Alterations in protein phosphatase 2A subunit interaction in human carcinomas of the lung and colon with mutations in the A beta subunit geneAnalysis of 11q21-24 loss of heterozygosity candidate target genes in breast cancer: indications of TSLC1 promoter hypermethylationProtein phosphatase 2A and its B56 regulatory subunit inhibit Wnt signaling in XenopusTranscriptional regulation of PP2A-A alpha is mediated by multiple factors including AP-2alpha, CREB, ETS-1, and SP-1Protein phosphatase 2A subunit gene haplotypes and proliferative breast disease modify breast cancer risk.Cyanobacterial Toxins of the Laurentian Great Lakes, Their Toxicological Effects, and Numerical Limits in Drinking WaterPhosphorylated protein phosphatase 2A determines poor outcome in patients with metastatic colorectal cancer.Essential requirement for PP2A inhibition by the oncogenic receptor c-KIT suggests PP2A reactivation as a strategy to treat c-KIT+ cancersCandidate tumour suppressor genes at 11q23-q24 in breast cancer: evidence of alterations in PIG8, a gene involved in p53-induced apoptosis.Role of a novel functional variant in the PPP2R1A promoter on the regulation of PP2A-Aalpha and the risk of hepatocellular carcinomaH2AX: functional roles and potential applications.Human cancer-associated mutations in the Aα subunit of protein phosphatase 2A increase lung cancer incidence in Aα knock-in and knockout mice.Allelic imbalance at chromosome 11 in head and neck squamous cell carcinoma in an Indian patient populationRestricted protein phosphatase 2A targeting by Merkel cell polyomavirus small T antigen.Mouse model for probing tumor suppressor activity of protein phosphatase 2A in diverse signaling pathways.MicroRNA-587 antagonizes 5-FU-induced apoptosis and confers drug resistance by regulating PPP2R1B expression in colorectal cancerPP2A Counterbalances Phosphorylation of pRB and Mitotic Proteins by Multiple CDKs: Potential Implications for PP2A Disruption in CancerImpaired expression of protein phosphatase 2A subunits enhances metastatic potential of human prostate cancer cells through activation of AKT pathway.Evaluation of PPP2R2A as a prostate cancer susceptibility gene: a comprehensive germline and somatic study.The role of PP2A A subunits in tumor suppressionAll roads lead to PP2A: exploiting the therapeutic potential of this phosphatase.Deregulation of the protein phosphatase 2A, PP2A in cancer: complexity and therapeutic options.Protein phosphatase 2A is essential to maintain active Wnt signaling and its Aβ tumor suppressor subunit is not expressed in colon cancer cells.FTY720 induces apoptosis of chronic myelogenous leukemia cells via dual activation of BIM and BID and overcomes various types of resistance to tyrosine kinase inhibitors.Alterations of ATM and CADM1 in chromosomal 11q22.3-23.2 region are associated with the development of invasive cervical carcinoma.The role of the amino acid residue at alpha1:189 in the binding of neuromuscular blocking agents to mouse and human muscle nicotinic acetylcholine receptors.Deregulation of the phosphatase, PP2A is a common event in breast cancer, predicting sensitivity to FTY720.Disruption of protein phosphatase 2A subunit interaction in human cancers with mutations in the A alpha subunit gene.PP2A impaired activity is a common event in acute myeloid leukemia and its activation by forskolin has a potent anti-leukemic effect.Loss of heterozygosity on chromosome 10p14-p15 in colorectal carcinoma.
P2860
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P2860
Alterations of the PPP2R1B gene located at 11q23 in human colorectal cancers
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2000 nî lūn-bûn
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2000 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
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2000 թվականի օգոստոսին հրատարակված գիտական հոդված
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2000年の論文
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2000年学术文章
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2000年学术文章
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2000年学术文章
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2000年学术文章
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2000年学术文章
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Alterations of the PPP2R1B gene located at 11q23 in human colorectal cancers
@ast
Alterations of the PPP2R1B gene located at 11q23 in human colorectal cancers
@en
Alterations of the PPP2R1B gene located at 11q23 in human colorectal cancers
@nl
type
label
Alterations of the PPP2R1B gene located at 11q23 in human colorectal cancers
@ast
Alterations of the PPP2R1B gene located at 11q23 in human colorectal cancers
@en
Alterations of the PPP2R1B gene located at 11q23 in human colorectal cancers
@nl
prefLabel
Alterations of the PPP2R1B gene located at 11q23 in human colorectal cancers
@ast
Alterations of the PPP2R1B gene located at 11q23 in human colorectal cancers
@en
Alterations of the PPP2R1B gene located at 11q23 in human colorectal cancers
@nl
P2093
P2860
P356
P1433
P1476
Alterations of the PPP2R1B gene located at 11q23 in human colorectal cancers
@en
P2093
P2860
P304
P356
10.1136/GUT.47.2.268
P407
P577
2000-08-01T00:00:00Z