The epigenetic modifier ubiquitin-specific protease 22 (USP22) regulates embryonic stem cell differentiation via transcriptional repression of sex-determining region Y-box 2 (SOX2).
about
USP22 is a positive regulator of NFATc2 on promoting IL2 expressionYin Yang 1 is associated with cancer stem cell transcription factors (SOX2, OCT4, BMI1) and clinical implicationUbiquitin-specific peptidase 22 functions and its involvement in diseaseThe Importance of Ubiquitination and Deubiquitination in Cellular ReprogrammingDeubiquitylation of deubiquitylasesEpigenetic regulation of the neural transcriptome and alcohol interference during development.Genetic predisposition to neuroblastoma mediated by a LMO1 super-enhancer polymorphism.Ubiquitin-specific peptidase 22, a histone deubiquitinating enzyme, is a novel poor prognostic factor for salivary adenoid cystic carcinoma.p38 mitogen-activated protein kinase inhibits USP22 transcription in HeLa cells.Stable oncogenic silencing in vivo by programmable and targeted de novo DNA methylation in breast cancer.Usp22 deficiency impairs intestinal epithelial lineage specification in vivoUbe2s regulates Sox2 stability and mouse ES cell maintenanceRecent advances in defining the ubiquitylome.Functions of SAGA in development and disease.SOX2 and cancer: current research and its implications in the clinicDUBs, the regulation of cell identity and disease.SIRT1 and Neural Cell Fate Determination.USP44 Is an Integral Component of N-CoR that Contributes to Gene Repression by Deubiquitinating Histone H2B.Regulation of pluripotency and differentiation by deubiquitinating enzymes.Concise Review: Fate Determination of Stem Cells by Deubiquitinating Enzymes.Targeting Deubiquitinating Enzymes in Glioblastoma Multiforme: Expectations and Challenges.Emerging role of DUBs in tumor metastasis and apoptosis: Therapeutic implication.Ubiquitin-specific protease 22 is a deubiquitinase of CCNB1.Differential landscape of non-CpG methylation in embryonic stem cells and neurons caused by DNMT3s.USP26 functions as a negative regulator of cellular reprogramming by stabilising PRC1 complex components.Dzip3 regulates developmental genes in mouse embryonic stem cells by reorganizing 3D chromatin conformation.Deubiquitinating enzymes regulate Hes1 stability and neuronal differentiation.RNF20 and histone H2B ubiquitylation exert opposing effects in Basal-Like versus luminal breast cancer.Targeting deubiquitinating enzymes in cancer stem cells.HDAC1 and HDAC3 underlie dynamic H3K9 acetylation during embryonic neurogenesis and in schizophrenia-like animals.Activation of gene expression by histone deubiquitinase OTLD1.Insights into the ubiquitin-proteasome system of human embryonic stem cells.
P2860
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P2860
The epigenetic modifier ubiquitin-specific protease 22 (USP22) regulates embryonic stem cell differentiation via transcriptional repression of sex-determining region Y-box 2 (SOX2).
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
The epigenetic modifier ubiqui ...... rmining region Y-box 2 (SOX2).
@en
The epigenetic modifier ubiquitin-specific protease 22
@nl
type
label
The epigenetic modifier ubiqui ...... rmining region Y-box 2 (SOX2).
@en
The epigenetic modifier ubiquitin-specific protease 22
@nl
prefLabel
The epigenetic modifier ubiqui ...... rmining region Y-box 2 (SOX2).
@en
The epigenetic modifier ubiquitin-specific protease 22
@nl
P2093
P2860
P356
P1476
The epigenetic modifier ubiqui ...... rmining region Y-box 2 (SOX2).
@en
P2093
John D Gearhart
Paul Esteso
Steven B McMahon
Timothy J Stanek
P2860
P304
24234-24246
P356
10.1074/JBC.M113.469783
P407
P577
2013-06-12T00:00:00Z