Characterization of sequence determinants within the carboxyl-terminal domain of chemokine receptor CCR5 that regulate signaling and receptor internalization.
about
Structural basis for the binding of the membrane-proximal C-terminal region of chemokine receptor CCR2 with the cytosolic regulator FROUNTHsc/Hsp70 interacting protein (hip) associates with CXCR2 and regulates the receptor signaling and traffickingThe structural basis of arrestin-mediated regulation of G-protein-coupled receptorsStructure modeling of all identified G protein-coupled receptors in the human genomeJM4 is a four-transmembrane protein binding to the CCR5 receptorAnalysis of ligand-stimulated CC chemokine receptor 5 (CCR5) phosphorylation in intact cells using phosphosite-specific antibodiesThe C-terminal domain LLKIL motif of CXCR2 is required for ligand-mediated polarization of early signals during chemotaxisThe IL sequence in the LLKIL motif in CXCR2 is required for full ligand-induced activation of Erk, Akt, and chemotaxis in HL60 cells.Phosphorylation of chemoattractant receptors regulates chemotaxis, actin reorganization and signal relay.Direct binding of a fragment of the Wiskott-Aldrich syndrome protein to the C-terminal end of the anaphylatoxin C5a receptor.Statins disrupt CCR5 and RANTES expression levels in CD4(+) T lymphocytes in vitro and preferentially decrease infection of R5 versus X4 HIV-1The bovine chemokine receptors and their mRNA abundance in mononuclear phagocytes.G protein-coupled receptor sorting to endosomes and lysosomes.Defective lymphocyte chemotaxis in beta-arrestin2- and GRK6-deficient mice.The role of palmitoylation in signalling, cellular trafficking and plasma membrane localization of protease-activated receptor-2.Variants of CCR5, which are permissive for HIV-1 infection, show distinct functional responses to CCL3, CCL4 and CCL5.Two di-leucine motifs regulate trafficking of mucolipin-1 to lysosomesARF6: a newly appreciated player in G protein-coupled receptor desensitization.Two mechanisms for human immunodeficiency virus type 1 inhibition by N-terminal modifications of RANTESCCR5 conformations are dynamic and modulated by localization, trafficking and G protein associationBeta-arrestin-2 regulates the development of allergic asthmaPotent Anti-HIV Chemokine Analogs Direct Post-Endocytic Sorting of CCR5Distinct mechanisms of agonist-induced endocytosis for human chemokine receptors CCR5 and CXCR4Analysis of Chemokine Receptor Trafficking by Site-Specific BiotinylationChemokine receptor internalization and intracellular trafficking.Functional roles of short sequence motifs in the endocytosis of membrane receptors.D6 and the atypical chemokine receptor family: novel regulators of immune and inflammatory processes.C-C chemokine receptor type five (CCR5): An emerging target for the control of HIV infection.Illuminating the life of GPCRstopPTM: a new module of dbPTM for identifying functional post-translational modifications in transmembrane proteins.Conformational HIV-1 envelope on particulate structures: a tool for chemokine coreceptor binding studies.Structural Diversity in Conserved Regions Like the DRY-Motif among Viral 7TM Receptors-A Consequence of Evolutionary Pressure?Phosphorylation of key serine residues is required for internalization of the complement 5a (C5a) anaphylatoxin receptor via a beta-arrestin, dynamin, and clathrin-dependent pathway.Arrestins: Critical Players in Trafficking of Many GPCRs.Palmitoylation is required for intracellular trafficking of influenza B virus NB protein and efficient influenza B virus growth in vitro.Induction of copper/zinc-superoxide dismutase by CCL5/CCR5 activation causes tumour necrosis factor-alpha and reactive oxygen species production in macrophages.CXCR1 and CXCR2 activation and regulation. Role of aspartate 199 of the second extracellular loop of CXCR2 in CXCL8-mediated rapid receptor internalization.Agonist-induced endocytosis of CC chemokine receptor 5 is clathrin dependent.Intracellular domains of CXCR3 that mediate CXCL9, CXCL10, and CXCL11 function.Galpha protein selectivity determinant specified by a viral chemokine receptor-conserved region in the C tail of the human herpesvirus 8 g protein-coupled receptor.
P2860
Q24305187-373CBFC3-237D-4A07-9576-B26AFE47129CQ24647176-A9DF9176-2D8C-4015-A1F1-73FBA0E167E1Q24657537-D1E539C7-8702-4A95-B9B0-43BCDC6523E4Q25256886-087A7E6D-D36C-4EBA-A709-6B72B79EAFA8Q28239006-7395CF7C-DC3F-494F-A3A9-ED46C1652BC7Q28572119-4E172D23-8644-47F4-80AA-EBD674CC69A6Q30487001-755AFC28-CD05-449F-9340-E03B8FF01EDAQ30496865-743D58A2-68A7-441B-B684-102C66A52374Q30550026-F72FF59E-B4DB-49B2-A042-C9C8078313DFQ31132474-01F80CBA-9EC5-40A9-B6AA-ED32534DC727Q33285482-1BC5062F-A1A4-458B-A381-2A40F40B52F8Q33636099-211B6F3A-BFFB-4CC1-8862-D49364E4F098Q33848408-6877A97A-8B23-459A-937F-51CF4FB178B2Q34064133-8969E67E-5EDA-4325-93EE-6D6F04F15DEBQ34091200-D8EBB190-D17E-4D26-AC6C-236642AC5F3FQ34362854-3BD9DE5E-0BEA-4E60-8115-9A4DA4CF627DQ34478343-45FB3D28-1B36-4FAF-A5E7-9B57BFF9C0C0Q34688600-EB110F66-8E80-4F24-A348-22DAC41F2207Q34823587-F456D1DE-AFC3-4FFB-874D-7185589518AEQ35106596-2C517B93-9F73-4BCF-87DA-37BD267BCC8DQ35242857-47D23882-20C8-4DD0-BC60-A921569EA996Q35617641-D92209C2-7258-40A8-B671-C287C87D4E80Q35670389-58E99EBB-B8A4-4285-8D62-120C103A8CF1Q36054360-B9453B5D-BF5F-436F-B361-6AA6906CC12FQ36184275-F3165BAE-A82A-4AB3-A094-D47630D1148FQ37362304-E17ED0C3-3B40-465B-AEAA-A82B096CA42BQ37364658-2A553002-B3E6-4AF1-99FE-C4CE17B89C43Q37463869-2370B710-7174-4EAF-82C9-266979AA32D8Q37551248-108B1A79-DA27-4854-A6CA-2178F0453067Q37661960-48142626-3F5C-4874-B1CB-BBB53C766906Q37834097-59EF0166-66F8-40BA-B0D5-5AA96ECD8D7CQ38035296-61E73960-54CE-4789-8F17-47DB8D9345EBQ38360195-AAD8866F-62B1-4F3B-B681-3330524FF7F1Q38521129-9625139B-BB8B-4FCD-9217-68B042A9739FQ39222038-928F7E4E-F496-4B29-892C-F7C6CC9BBB5CQ39915079-62ABAE0A-7F0A-41D0-8F07-95CD9FF8812EQ40186508-68755774-901E-4532-BD2E-4737C24CB7C4Q40481969-A31F0593-2F2E-445C-A89E-2A33EA9D8829Q40554316-28ABFE3E-93BA-48F2-B59C-7B54B4D15416Q40589951-19F1792A-B604-49BF-891E-3C4220D9C1B5
P2860
Characterization of sequence determinants within the carboxyl-terminal domain of chemokine receptor CCR5 that regulate signaling and receptor internalization.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Characterization of sequence d ...... and receptor internalization.
@en
Characterization of sequence d ...... and receptor internalization.
@nl
type
label
Characterization of sequence d ...... and receptor internalization.
@en
Characterization of sequence d ...... and receptor internalization.
@nl
prefLabel
Characterization of sequence d ...... and receptor internalization.
@en
Characterization of sequence d ...... and receptor internalization.
@nl
P2093
P2860
P356
P1476
Characterization of sequence d ...... and receptor internalization.
@en
P2093
P2860
P304
34408-34418
P356
10.1074/JBC.M102782200
P407
P577
2001-07-11T00:00:00Z