Two di-leucine motifs regulate trafficking of mucolipin-1 to lysosomes
about
Neurologic, gastric, and opthalmologic pathologies in a murine model of mucolipidosis type IVThe role of TRPMLs in endolysosomal trafficking and functionLysosomal membrane proteins and their central role in physiologyMucolipidosis type IV: an updateMacroautophagy is defective in mucolipin-1-deficient mouse neuronsConstitutive activity of TRPML2 and TRPML3 channels versus activation by low extracellular sodium and small moleculesLysosomal trafficking functions of mucolipin-1 in murine macrophagesSmall molecule activators of TRPML3Activating mutations of the TRPML1 channel revealed by proline-scanning mutagenesis.Constitutive activity of the human TRPML2 channel induces cell degenerationRab11a-positive compartments in proximal tubule cells sort fluid-phase and membrane cargo.Novel roles for the MiTF/TFE family of transcription factors in organelle biogenesis, nutrient sensing, and energy homeostasisHepatitis B virus X protein inhibits autophagic degradation by impairing lysosomal maturation.Mucolipins: Intracellular TRPML1-3 channelsHeteromultimeric TRPML channel assemblies play a crucial role in the regulation of cell viability models and starvation-induced autophagyTwo dileucine motifs mediate late endosomal/lysosomal targeting of transmembrane protein 192 (TMEM192) and a C-terminal cysteine residue is responsible for disulfide bond formation in TMEM192 homodimers.The calcium channel mucolipin-3 is a novel regulator of trafficking along the endosomal pathwayHyperphosphorylation of polycystin-2 at a critical residue in disease reveals an essential role for polycystin-1-regulated dephosphorylation.Lysosomal physiology.LAPTMs regulate lysosomal function and interact with mucolipin 1: new clues for understanding mucolipidosis type IV.Differential mechanisms of action of the mucolipin synthetic agonist, ML-SA1, on insect TRPML and mammalian TRPML1.Mucolipin-2 localizes to the Arf6-associated pathway and regulates recycling of GPI-APs.Constitutive activity of TRP channels methods for measuring the activity and its outcome.Transient receptor potential mucolipin 1 (TRPML1) and two-pore channels are functionally independent organellar ion channelsTRPML: transporters of metals in lysosomes essential for cell survival?Transcriptional activation of lysosomal exocytosis promotes cellular clearance.Loss of lysosomal ion channel transient receptor potential channel mucolipin-1 (TRPML1) leads to cathepsin B-dependent apoptosis.Role of protein kinase d in Golgi exit and lysosomal targeting of the transmembrane protein, Mcoln1.A Novel Di-Leucine Motif at the N-Terminus of Human Organic Solute Transporter Beta Is Essential for Protein Association and Membrane Localization.Phosphoinositide isoforms determine compartment-specific ion channel activityRole of TRP channels in the regulation of the endosomal pathway.Activating mutation in a mucolipin transient receptor potential channel leads to melanocyte loss in varitint-waddler mice.The mucolipidosis IV Ca2+ channel TRPML1 (MCOLN1) is regulated by the TOR kinase.Drosophila TRPML is required for TORC1 activationNovel Role of TRPML2 in the Regulation of the Innate Immune ResponseAcid-sensing ion channel (ASIC) 4 predominantly localizes to an early endosome-related organelle upon heterologous expressionThe nutrient-responsive transcription factor TFE3 promotes autophagy, lysosomal biogenesis, and clearance of cellular debrisThe mucolipin-2 (TRPML2) ion channel: a tissue-specific protein crucial to normal cell function.Impaired myelination and reduced brain ferric iron in the mouse model of mucolipidosis IV.Cell biology of polycystin-2.
P2860
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P2860
Two di-leucine motifs regulate trafficking of mucolipin-1 to lysosomes
description
2006 nî lūn-bûn
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2006 թուականի Մարտին հրատարակուած գիտական յօդուած
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2006 թվականի մարտին հրատարակված գիտական հոդված
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2006年の論文
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2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
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name
Two di-leucine motifs regulate trafficking of mucolipin-1 to lysosomes
@ast
Two di-leucine motifs regulate trafficking of mucolipin-1 to lysosomes
@en
Two di-leucine motifs regulate trafficking of mucolipin-1 to lysosomes
@nl
type
label
Two di-leucine motifs regulate trafficking of mucolipin-1 to lysosomes
@ast
Two di-leucine motifs regulate trafficking of mucolipin-1 to lysosomes
@en
Two di-leucine motifs regulate trafficking of mucolipin-1 to lysosomes
@nl
prefLabel
Two di-leucine motifs regulate trafficking of mucolipin-1 to lysosomes
@ast
Two di-leucine motifs regulate trafficking of mucolipin-1 to lysosomes
@en
Two di-leucine motifs regulate trafficking of mucolipin-1 to lysosomes
@nl
P2860
P1433
P1476
Two di-leucine motifs regulate trafficking of mucolipin-1 to lysosomes
@en
P2093
Rosa Puertollano
Silvia Vergarajauregui
P2860
P304
P356
10.1111/J.1600-0854.2006.00387.X
P577
2006-03-01T00:00:00Z