Selective inhibition of p300 HAT blocks cell cycle progression, induces cellular senescence, and inhibits the DNA damage response in melanoma cells.
about
The multifaceted role of lysine acetylation in cancer: prognostic biomarker and therapeutic targetHistone acetyltransferases: challenges in targeting bi-substrate enzymesKATs in cancer: functions and therapiesProtein lysine acetylation by p300/CBPAcetylation Reader Proteins: Linking Acetylation Signaling to Genome Maintenance and CancerHistone acetyltransferases and histone deacetylases in B- and T-cell development, physiology and malignancyProstate cancer epigenetics and its clinical implicationsThe soy-derived peptide Lunasin inhibits invasive potential of melanoma initiating cellsKrüppel-like factor 4 (KLF4) regulates the miR-183~96~182 cluster under physiologic and pathologic conditions.P300-dependent STAT3 acetylation is necessary for angiotensin II-induced pro-fibrotic responses in renal tubular epithelial cells.Decreased expression of nuclear p300 is associated with disease progression and worse prognosis of melanoma patientsHistone acetyltransferase inhibitor II induces apoptosis in glioma cell lines via the p53 signaling pathway.Loss of CITED1, an MITF regulator, drives a phenotype switch in vitro and can predict clinical outcome in primary melanoma tumours.Acetylation-dependent function of human single-stranded DNA binding protein 1.CITED2 silencing sensitizes cancer cells to cisplatin by inhibiting p53 trans-activation and chromatin relaxation on the ERCC1 DNA repair gene.Retinoblastoma Binding Protein 4 Modulates Temozolomide Sensitivity in Glioblastoma by Regulating DNA Repair Proteins.Inhibition of p300 histone acetyltransferase activity in palate mesenchyme cells attenuates Wnt signaling via aberrant E-cadherin expression.Trichostatin A Enhances the Apoptotic Potential of Palladium Nanoparticles in Human Cervical Cancer Cells.Regulatory variation: an emerging vantage point for cancer biology.Driver mutations of cancer epigenomes.Acetylation of Mammalian ADA3 Is Required for Its Functional Roles in Histone Acetylation and Cell Proliferation.Exploitation of EP300 and CREBBP Lysine Acetyltransferases by Cancer.Combination of palladium nanoparticles and tubastatin-A potentiates apoptosis in human breast cancer cells: a novel therapeutic approach for cancer.Epigenetic regulation of interleukin-8 expression by class I HDAC and CBP in ovarian cancer cells.HDAC8 and STAT3 repress BMF gene activity in colon cancer cells.Overexpression of p300 correlates with poor prognosis in patients with cutaneous squamous cell carcinoma.Targeting the CoREST complex with dual histone deacetylase and demethylase inhibitors.CREBBP and p300 lysine acetyl transferases in the DNA damage response.KAT3B-p300 and H3AcK18/H3AcK14 levels are prognostic markers for kidney ccRCC tumor aggressiveness and target of KAT inhibitor CPTH2.Replication-dependent histone isoforms: a new source of complexity in chromatin structure and functionCBP and P300 regulate distinct gene networks required for human primary myoblast differentiation and muscle integrityRecent advances in the understanding and treatment of acute myeloid leukemia
P2860
Q26744292-D9C674A4-CD80-408E-AA71-70D73EAA297AQ26745642-D12368DE-E8B5-4D98-9B87-43273DDFBADBQ26859355-22F943D8-33D6-48B5-95E0-87AA8B7BD06DQ27021749-E83DB5EC-E8A9-4F08-84A0-4C6785981371Q28076086-0CB6E334-EE79-4117-8EDF-928EAC182DB8Q28082536-7438F0E8-CFC7-4777-B0D0-778A8A5B57A0Q28829460-E3A13F9F-A5D6-449E-BD54-D64D582F9B11Q33648931-6635D2B9-DDDF-4DDC-A45B-2AF5962EC5B6Q33688638-B7874000-C21E-4C9E-8C68-A3BF66C640C2Q34138337-C5BA2B2A-93D4-40C0-80D6-554351422321Q35010007-D4C91C86-07A0-45E0-8B27-F72CF6244A1BQ35063895-6C5DFB09-D117-40B7-8E1E-C849FA322CF1Q35145922-20E4F73D-CAF1-487D-8A61-82594140C828Q36299145-93DF6857-3F37-4AD1-AE95-D2D797E433C4Q36370912-23CE3844-B5C2-4501-9294-33798F4C63AFQ36723302-8C201D64-7EAC-4759-9228-E2FA3A283A9AQ36757654-FF33BAD3-77FC-49FF-919D-41F57C2E1272Q37210234-00585AB0-DE54-451B-ACEC-06D930831D59Q38164307-00859ABC-3F32-4FA8-ADDC-046538B595A4Q38639828-5E74DA77-0A23-4BC2-9BB4-C3200117EADAQ38758681-A5DEFDE9-F5B5-4AFE-9549-E596EE4E8D59Q39018415-D3A35283-22C1-4066-8B10-4915365CC892Q41382946-77A89687-5839-4FCA-9E29-FC1DEE70B825Q42378478-0FBAFB7C-1100-4082-9140-E913D0611A31Q42703854-3909163B-D54E-44B2-8F4C-9546518632FBQ46449536-C2FDF618-EDBE-4C27-A5AC-1F68CE285C47Q47199869-24F2EE36-6621-4A16-8312-70FAB57087A2Q47369126-49A88707-4CCC-4354-BD23-6283F0605400Q52597611-4A7A2026-9AB0-498C-9C2C-0C130ACAEC59Q58700196-6BF1968B-379E-4873-98FB-4D123D05C595Q58721602-CF546145-098B-4D91-84AC-16564B55ACBCQ58799330-88A3F3E8-023E-47D5-8F4B-1C11BC61A546
P2860
Selective inhibition of p300 HAT blocks cell cycle progression, induces cellular senescence, and inhibits the DNA damage response in melanoma cells.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Selective inhibition of p300 H ...... ge response in melanoma cells.
@en
Selective inhibition of p300 H ...... ge response in melanoma cells.
@nl
type
label
Selective inhibition of p300 H ...... ge response in melanoma cells.
@en
Selective inhibition of p300 H ...... ge response in melanoma cells.
@nl
prefLabel
Selective inhibition of p300 H ...... ge response in melanoma cells.
@en
Selective inhibition of p300 H ...... ge response in melanoma cells.
@nl
P2093
P2860
P356
P1476
Selective inhibition of p300 H ...... age response in melanoma cells
@en
P2093
Beverley M Dancy
Cecilia A Larocca
Courtney Elm
David Meyers
Erin M Bowers
Izabela P Panova
Lisa Lareau
Mark S Eller
Philip A Cole
P2860
P2888
P304
P356
10.1038/JID.2013.187
P407
P577
2013-04-18T00:00:00Z