The GRP1 PH domain, like the AKT1 PH domain, possesses a sentry glutamate residue essential for specific targeting to plasma membrane PI(3,4,5)P(3).
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Structural basis for membrane recruitment and allosteric activation of cytohesin family Arf GTPase exchange factorsCancer associated E17K mutation causes rapid conformational drift in AKT1 pleckstrin homology (PH) domainRegulation of insulin signaling by the phosphatidylinositol 3,4,5-triphosphate phosphatase SKIP through the scaffolding function of Pak1Membrane docking geometry of GRP1 PH domain bound to a target lipid bilayer: an EPR site-directed spin-labeling and relaxation study.Molecular mechanism of membrane binding of the GRP1 PH domain.Mechanism for phosphoinositide selectivity and activation of TRPV1 ion channels.Lipid targeting domain with dual-membrane specificity that expands the diversity of intracellular targeting reactions.The cytohesin paralog Sec7 of Dictyostelium discoideum is required for phagocytosis and cell motility.A Five-Gene Expression Signature Predicts Clinical Outcome of Ovarian Serous Cystadenocarcinoma.Structure and lipid-binding properties of the kindlin-3 pleckstrin homology domain.Interplay between phosphoinositide lipids and calcium signals at the leading edge of chemotaxing ameboid cells.Differential effects of AKT1(p.E17K) expression on human mammary luminal epithelial and myoepithelial cells.Association of Peripheral Membrane Proteins with Membranes: Free Energy of Binding of GRP1 PH Domain with Phosphatidylinositol Phosphate-Containing Model Bilayers.The PH domain of phosphoinositide-dependent kinase-1 exhibits a novel, phospho-regulated monomer-dimer equilibrium with important implications for kinase domain activation: single-molecule and ensemble studies
P2860
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P2860
The GRP1 PH domain, like the AKT1 PH domain, possesses a sentry glutamate residue essential for specific targeting to plasma membrane PI(3,4,5)P(3).
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
The GRP1 PH domain, like the A ...... plasma membrane PI(3,4,5)P(3).
@en
The GRP1 PH domain, like the A ...... plasma membrane PI(3,4,5)P(3).
@nl
type
label
The GRP1 PH domain, like the A ...... plasma membrane PI(3,4,5)P(3).
@en
The GRP1 PH domain, like the A ...... plasma membrane PI(3,4,5)P(3).
@nl
prefLabel
The GRP1 PH domain, like the A ...... plasma membrane PI(3,4,5)P(3).
@en
The GRP1 PH domain, like the A ...... plasma membrane PI(3,4,5)P(3).
@nl
P2093
P2860
P356
P1433
P1476
The GRP1 PH domain, like the A ...... plasma membrane PI(3,4,5)P(3).
@en
P2093
Carissa Pilling
Joseph J Falke
Kyle E Landgraf
P2860
P304
P356
10.1021/BI2011306
P407
P577
2011-10-19T00:00:00Z