Supramolecular self-assembled nanoparticles mediate oral delivery of therapeutic TNF-α siRNA against systemic inflammation. - Wikidata - wikimedia - TriplyDB

Supramolecular self-assembled nanoparticles mediate oral delivery of therapeutic TNF-α siRNA against systemic inflammation.

Supramolecular self-assembled nanoparticles mediate oral delivery of therapeutic TNF-α siRNA against systemic inflammation.

http://www.wikidata.org/entity/Q39162056

about

Polymeric nanoparticle technologies for oral drug delivery.Macrophage targeted theranostics as personalized nanomedicine strategies for inflammatory diseases.A rationally designed nanoparticle for RNA interference therapy in B-lineage lymphoid malignancies Development of Polypeptide-based Nanoparticles for Non-viral Delivery of CD22 RNA Trans-splicing Molecule as a New Precision Medicine Candidate Against B-lineage ALL.Helical antimicrobial polypeptides with radial amphiphilicity.SiRNA Crosslinked Nanoparticles for the Treatment of Inflammation-induced Liver Injury.Recent advances in amino acid N-carboxyanhydrides and synthetic polypeptides: chemistry, self-assembly and biological applications.Targeted delivery systems for biological therapies of inflammatory diseases.Ionic α-helical polypeptides toward nonviral gene delivery.Polypeptides with quaternary phosphonium side chains: synthesis, characterization, and cell-penetrating properties.Targeting leukemic stem cells with multifunctional bioactive polypeptide nanoparticles.Novel delivery system for T-oligo using a nanocomplex formed with an alpha helical peptide for melanoma therapy.Polymers in the Co-delivery of siRNA and Anticancer Drugs for the Treatment of Drug-resistant Cancers.Therapeutic approaches for the delivery of TNF-α siRNA.Oral nucleic acid therapy using multicompartmental delivery systems.Peptides, polypeptides and peptide-polymer hybrids as nucleic acid carriers.Bacteria-Assisted Activation of Antimicrobial Polypeptides by a Random-Coil to Helix Transition.Serum-resistant, reactive oxygen species (ROS)-potentiated gene delivery in cancer cells mediated by fluorinated, diselenide-crosslinked polyplexes.Maximizing gene delivery efficiencies of cationic helical polypeptides via balanced membrane penetration and cellular targeting.The effect of side-chain functionality and hydrophobicity on the gene delivery capabilities of cationic helical polypeptides.Trigger-responsive, fast-degradable poly(β-amino ester)s for enhanced DNA unpackaging and reduced toxicity.Virus-Mimicking Chimaeric Polymersomes Boost Targeted Cancer siRNA Therapy In Vivo.Synthetic polypeptides: from polymer design to supramolecular assembly and biomedical application.Oral delivery of siRNA lipid nanoparticles: Fate in the GI tract.Evaluation of Maltose-Based Cationic Liposomes with Different Hydrophobic Tails for Plasmid DNA Delivery.Polypeptide vesicles with densely packed multilayer membranes.Nonviral gene editing via CRISPR/Cas9 delivery by membrane-disruptive and endosomolytic helical polypeptide.Knockdown of TNF‑α alleviates acute lung injury in rats with intestinal ischemia and reperfusion injury by upregulating IL‑10 expression.Bilirubin Nanoparticles as a Nanomedicine for Anti-inflammation Therapy.

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P2860

Supramolecular self-assembled nanoparticles mediate oral delivery of therapeutic TNF-α siRNA against systemic inflammation.

http://www.wikidata.org/entity/Q39162056

description

2013 nî lūn-bûn

@nan

2013年の論文

@ja

2013年論文

@yue

2013年論文

@zh-hant

2013年論文

@zh-hk

2013年論文

@zh-mo

2013年論文

@zh-tw

2013年论文

@wuu

2013年论文

@zh

2013年论文

@zh-cn

name

Supramolecular self-assembled ...... against systemic inflammation.

@en

Supramolecular self-assembled ...... against systemic inflammation.

@nl

type

label

Supramolecular self-assembled ...... against systemic inflammation.

@en

Supramolecular self-assembled ...... against systemic inflammation.

@nl

prefLabel

Supramolecular self-assembled ...... against systemic inflammation.

@en

Supramolecular self-assembled ...... against systemic inflammation.

@nl

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Supramolecular self-assembled ...... against systemic inflammation.

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Catherine Yao

http://www.w3.org/2001/XMLSchema#string

Isthier Chaudhury

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Jianjun Cheng

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Kyung Hoon Kim

http://www.w3.org/2001/XMLSchema#string

Lichen Yin

http://www.w3.org/2001/XMLSchema#string

Nan Zheng

http://www.w3.org/2001/XMLSchema#string

Nathan P Gabrielson

http://www.w3.org/2001/XMLSchema#string

Qiuhao Qu

http://www.w3.org/2001/XMLSchema#string

Ziyuan Song

http://www.w3.org/2001/XMLSchema#string

P2860

Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles

Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes

Transport of chitosan-DNA nanoparticles in human intestinal M-cell model versus normal intestinal enterocytes.

Multiplexed supramolecular self-assembly for non-viral gene delivery.

Chitosan/siRNA nanoparticle-mediated TNF-alpha knockdown in peritoneal macrophages for anti-inflammatory treatment in a murine arthritis model.

siRNA-mediated gene silencing in vitro and in vivo.

Functional TNFα gene silencing mediated by polyethyleneimine/TNFα siRNA nanocomplexes in inflamed colon.

Oral TNF-α gene silencing using a polymeric microsphere-based delivery system for the treatment of inflammatory bowel disease

Orally delivered thioketal nanoparticles loaded with TNF-α-siRNA target inflammation and inhibit gene expression in the intestines.

Protection against TNFα-dependent liver toxicity by intraperitoneal liposome delivered DsiRNA targeting TNFα in vivo

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5757-5761

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10.1002/ANIE.201209991

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