Class I histone deacetylase inhibition modulates metalloproteinase expression and blocks cytokine-induced cartilage degradation. - Wikidata - wikimedia - TriplyDB

Class I histone deacetylase inhibition modulates metalloproteinase expression and blocks cytokine-induced cartilage degradation.

Class I histone deacetylase inhibition modulates metalloproteinase expression and blocks cytokine-induced cartilage degradation.

http://www.wikidata.org/entity/Q39168362

about

The microRNA-29 family in cartilage homeostasis and osteoarthritis Epigenetic Regulation of Matrix Metalloproteinase-1 and -3 Expression in Mycobacterium tuberculosis Infection.Histone deacetylase 3 supports endochondral bone formation by controlling cytokine signaling and matrix remodeling.p16INK4a and its regulator miR-24 link senescence and chondrocyte terminal differentiation-associated matrix remodeling in osteoarthritis.Histone deacetylase 4 alters cartilage homeostasis in human osteoarthritis.Detecting new microRNAs in human osteoarthritic chondrocytes identifies miR-3085 as a human, chondrocyte-selective, microRNA.Upregulation of Bone Morphogenetic Protein-2 Synthesis and Consequent Collagen II Expression in Leptin-stimulated Human Chondrocytes Histone deacetylase inhibition activates Nrf2 and protects against osteoarthritis Histone Deacetylases in Bone Development and Skeletal Disorders.MicroRNA-381 Regulates Chondrocyte Hypertrophy by Inhibiting Histone Deacetylase 4 Expression.Histone deacetylase 3 regulates the inflammatory gene expression programme of rheumatoid arthritis fibroblast-like synoviocytes Inflammation and epigenetic regulation in osteoarthritis.Cellular senescence in osteoarthritis pathology.SOCS1 Regulates Apoptosis and Inflammation by Inhibiting IL-4 Signaling in IL-1β-Stimulated Human Osteoarthritic Chondrocytes.Osteoarthritis year in review 2013: biology.Epigenetics of osteoarticular diseases: recent developments.Chromatin modifiers and histone modifications in bone formation, regeneration, and therapeutic intervention for bone-related disease.The Epigenomic Landscape in Osteoarthritis.Histone Deacetylases in Cartilage Homeostasis and Osteoarthritis.Protection against murine osteoarthritis by inhibition of the 26S proteasome and lysine-48 linked ubiquitination.Histone deacetylase inhibitor vorinostat (SAHA, MK0683) perturb miR-9-MCPIP1 axis to block IL-1β-induced IL-6 expression in human OA chondrocytes.Induction of histone deacetylases (HDACs) in human abdominal aortic aneurysm: therapeutic potential of HDAC inhibitors Poly(ADP-ribose) polymerase 1 inhibition prevents interleukin-1β-induced inflammation in human osteoarthritic chondrocytes.Histone Deacetylase Inhibitor Vorinostat (SAHA) Suppresses IL-1β-Induced Matrix Metallopeptidase-13 Expression by Inhibiting IL-6 in Osteoarthritis Chondrocyte Histone Deacetylase Inhibitory Approaches for the Management of Osteoarthritis Molecular mechanisms of suberoylanilide hydroxamic acid in the inhibition of TGF-β1-mediated canine corneal fibrosis.Sulforaphane represses matrix-degrading proteases and protects cartilage from destruction in vitro and in vivo.Chaperonin 60 regulation of SOX9 ubiquitination mitigates the development of knee osteoarthritis.Epigenetics in osteoarthritis: Potential of HDAC inhibitors as therapeutics.MicroRNA-193b-3p regulates chondrogenesis and chondrocyte metabolism by targeting HDAC3.Inhibiting histone deacetylase 1 suppresses both inflammation and bone loss in arthritis Reduced Activity of HDAC3 and Increased Acetylation of Histones H3 in Peripheral Blood Mononuclear Cells of Patients with Rheumatoid Arthritis

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P2860

Class I histone deacetylase inhibition modulates metalloproteinase expression and blocks cytokine-induced cartilage degradation.

http://www.wikidata.org/entity/Q39168362

description

2013 nî lūn-bûn

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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2013年论文

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2013年论文

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name

Class I histone deacetylase in ...... induced cartilage degradation.

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Class I histone deacetylase in ...... induced cartilage degradation.

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Class I histone deacetylase in ...... induced cartilage degradation.

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Class I histone deacetylase in ...... induced cartilage degradation.

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Class I histone deacetylase in ...... induced cartilage degradation.

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Arthritis and Rheumatism

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Class I histone deacetylase in ...... -induced cartilage degradation

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Andrew D Rowan

http://www.w3.org/2001/XMLSchema#string

Auriane P M Destrument

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Ian M Clark

http://www.w3.org/2001/XMLSchema#string

Jenny L Scott

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Kirsty L Culley

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Matt J Barter

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Steve Fenwick

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Tracey E Swingler

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Wang Hui

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P2860

HDAC6 is a microtubule-associated deacetylase

Crystal structure of a eukaryotic zinc-dependent histone deacetylase, human HDAC8, complexed with a hydroxamic acid inhibitor

Histone deacetylase inhibitors modulate metalloproteinase gene expression in chondrocytes and block cartilage resorption

Lysine acetylation targets protein complexes and co-regulates major cellular functions

Expression profiling of metalloproteinases and their inhibitors in cartilage

Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells

Vorinostat: a new oral histone deacetylase inhibitor approved for cutaneous T-cell lymphoma.

Expression profiling of metalloproteinases and their inhibitors in synovium and cartilage.

Anti-rheumatic activities of histone deacetylase (HDAC) inhibitors in vivo in collagen-induced arthritis in rodents.

Osteoarthritis - an untreatable disease?

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1822-1830

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scholarly article

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10.1002/ART.37965

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7

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65

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David Alan Young

Rose K Davidson

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2013-07-01T00:00:00Z

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23575963

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