Effects of simultaneous knockdown of HER2 and PTK6 on malignancy and tumor progression in human breast cancer cells.
about
Evolution of breast cancer therapeutics: Breast tumour kinase's role in breast cancer and hope for breast tumour kinase targeted therapyPTK6/BRK is expressed in the normal mammary gland and activated at the plasma membrane in breast tumors.Breast tumor kinase (Brk/PTK6) is a mediator of hypoxia-associated breast cancer progression.Secreted uPAR isoform 2 (uPAR7b) is a novel direct target of miR-221.PTK6 inhibition promotes apoptosis of Lapatinib-resistant Her2(+) breast cancer cells by inducing Bim.Protein tyrosine kinase 6 promotes ERBB2-induced mammary gland tumorigenesis in the mouse.uPAR enhances malignant potential of triple-negative breast cancer by directly interacting with uPA and IGF1R.Three-dimensional microtissues essentially contribute to preclinical validations of therapeutic targets in breast cancer.Therapeutic siRNA for drug-resistant HER2-positive breast cancer.MiR-221/-222 differentiate prognostic groups in advanced breast cancers and influence cell invasion.Protein tyrosine kinase 6 regulates mammary gland tumorigenesis in mouse models.miR-1470 mediates lapatinib induced p27 upregulation by targeting c-jun.Additive impact of HER2-/PTK6-RNAi on interactions with HER3 or IGF-1R leads to reduced breast cancer progression in vivo.Potentially functional variants in lncRNAs are associated with breast cancer risk in a Chinese population.GLUL Promotes Cell Proliferation in Breast Cancer.
P2860
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P2860
Effects of simultaneous knockdown of HER2 and PTK6 on malignancy and tumor progression in human breast cancer cells.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Effects of simultaneous knockd ...... in human breast cancer cells.
@en
Effects of simultaneous knockd ...... in human breast cancer cells.
@nl
type
label
Effects of simultaneous knockd ...... in human breast cancer cells.
@en
Effects of simultaneous knockd ...... in human breast cancer cells.
@nl
prefLabel
Effects of simultaneous knockd ...... in human breast cancer cells.
@en
Effects of simultaneous knockd ...... in human breast cancer cells.
@nl
P2093
P50
P1476
Effects of simultaneous knockd ...... in human breast cancer cells.
@en
P2093
Heinz Höfler
Jana Seiler
Karin Mengele
Manfred Schmitt
Michaela Aubele
Natalie Ludyga
P304
P356
10.1158/1541-7786.MCR-12-0378
P577
2013-01-30T00:00:00Z