A CHO cell line engineered to express XBP1 and ERO1-Lα has increased levels of transient protein expression.
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P1343
N-Glycan-based ER Molecular Chaperone and Protein Quality Control System: The Calnexin Binding CycleUsing molecular markers to characterize productivity in Chinese hamster ovary cell lines.Fab-dsFv: A bispecific antibody format with extended serum half-life through albumin binding.Proteins improving recombinant antibody production in mammalian cells.The endoplasmic reticulum and unfolded protein response in the control of mammalian recombinant protein production.The effect of the unfolded protein response on the production of recombinant proteins in plants.Development of a fluorescent reporter system for monitoring ER stress in Chinese hamster ovary cells and its application for therapeutic protein productionNew Mammalian Expression Systems.Use of a protein engineering strategy to overcome limitations in the production of "Difficult to Express" recombinant proteins.Development of Genetically Modified Chinese Hamster Ovary Host Cells for the Enhancement of Recombinant Tissue Plasminogen Activator ExpressionTranscriptional and post-transcriptional targeting for enhanced transient gene expression in CHO cells.CHO-S antibody titers >1 gram/liter using flow electroporation-mediated transient gene expression followed by rapid migration to high-yield stable cell lines.A high cell density transient transfection system for therapeutic protein expression based on a CHO GS-knockout cell line: process development and product quality assessment.High-throughput mAb expression and purification platform based on transient CHO.A high-yielding CHO transient system: coexpression of genes encoding EBNA-1 and GS enhances transient protein expression.Extending the half-life of a fab fragment through generation of a humanized anti-human serum albumin Fv domain: An investigation into the correlation between affinity and serum half-life.How does mild hypothermia affect monoclonal antibody glycosylation?NF-κB, CRE and YY1 elements are key functional regulators of CMV promoter-driven transient gene expression in CHO cells.Versatile microscale screening platform for improving recombinant protein productivity in Chinese hamster ovary cells.Exploring cellular behavior under transient gene expression and its impact on mAb productivity and Fc-glycosylation.Polymer-mediated flocculation of transient CHO cultures as a simple, high throughput method to facilitate antibody discovery.Inhibition of IRE1α-mediated XBP1 mRNA cleavage by XBP1 reveals a novel regulatory process during the unfolded protein response.Advancements in mammalian cell transient gene expression (TGE) technology for accelerated production of biologics.Generation of stable Chinese hamster ovary pools yielding antibody titers of up to 7.6 g/L using the piggyBac transposon system.Preselection of recombinant gene integration sites enabling high transcription rates in CHO cells using alternate start codons and recombinase mediated cassette exchange.Large-Scale Transient Transfection of Chinese Hamster Ovary Cells in Suspension.Comparison of three transposons for the generation of highly productive recombinant CHO cell pools and cell lines.Integrated cell and process engineering for improved transient production of a "difficult-to-express" fusion protein by CHO cells.Transcriptional and post-transcriptional limitations of high-yielding, PEI-mediated transient transfection with CHO and HEK-293E cells.Mild hypothermia upregulates myc and xbp1s expression and improves anti-TNFα production in CHO cells.Endoplasmic reticulum oxidoreductin 1α mediates hepatic endoplasmic reticulum stress in homocysteine-induced atherosclerosis.
P2860
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P2860
A CHO cell line engineered to express XBP1 and ERO1-Lα has increased levels of transient protein expression.
description
2013 nî lūn-bûn
@nan
2013年の論文
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2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
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2013年論文
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2013年论文
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2013年论文
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2013年论文
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name
A CHO cell line engineered to ...... transient protein expression.
@en
A CHO cell line engineered to ...... transient protein expression.
@nl
type
label
A CHO cell line engineered to ...... transient protein expression.
@en
A CHO cell line engineered to ...... transient protein expression.
@nl
prefLabel
A CHO cell line engineered to ...... transient protein expression.
@en
A CHO cell line engineered to ...... transient protein expression.
@nl
P2093
P2860
P356
P1476
A CHO cell line engineered to ...... transient protein expression.
@en
P2093
Alan Dickson
Andy Ventom
Bernie Sweeney
Catherine Page
Hanna Hailu
James Heads
Katharine Cain
Kaushik Sarkar
Paul Stephens
Shirley Peters
P2860
P304
P356
10.1002/BTPR.1693
P4510
P577
2013-03-20T00:00:00Z