How does mild hypothermia affect monoclonal antibody glycosylation?
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Effect of Temperature Downshift on the Transcriptomic Responses of Chinese Hamster Ovary Cells Using Recombinant Human Tissue Plasminogen Activator Production Culture.Quantitative intracellular flux modeling and applications in biotherapeutic development and production using CHO cell cultures.A semi-empirical glycosylation model of a camelid monoclonal antibody under hypothermia cell culture conditions.Model-based investigation of intracellular processes determining antibody Fc-glycosylation under mild hypothermia.A control strategy to investigate the relationship between specific productivity and high-mannose glycoforms in CHO cells.Glycosylation of monoclonal antibody products: Current status and future prospects.What can mathematical modelling say about CHO metabolism and protein glycosylation?A theoretical estimate for nucleotide sugar demand towards Chinese Hamster Ovary cellular glycosylation.A Markov chain model for N-linked protein glycosylation--towards a low-parameter tool for model-driven glycoengineering.Understanding the impact of different bioprocess conditions on monoclonal antibody glycosylation in CHO cell cultures through experimental and computational analyses.Exploring cellular behavior under transient gene expression and its impact on mAb productivity and Fc-glycosylation.Cascading effect in bioprocessing-The impact of mild hypothermia on CHO cell behavior and host cell protein composition.Animal Cell Expression Systems.Intracellular response to process optimization and impact on productivity and product aggregates for a high-titer CHO cell process.Controlling the time evolution of mAb N-linked glycosylation, Part I: Microbioreactor experiments.Parallel experimental design and multivariate analysis provides efficient screening of cell culture media supplements to improve biosimilar product quality.Mild hypothermic culture conditions affect residual host cell protein composition post-Protein A chromatography.Mild hypothermia upregulates myc and xbp1s expression and improves anti-TNFα production in CHO cells.High glucose and low specific cell growth but not mild hypothermia improve specific r-protein productivity in chemostat culture of CHO cells
P2860
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P2860
How does mild hypothermia affect monoclonal antibody glycosylation?
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
How does mild hypothermia affect monoclonal antibody glycosylation?
@en
type
label
How does mild hypothermia affect monoclonal antibody glycosylation?
@en
prefLabel
How does mild hypothermia affect monoclonal antibody glycosylation?
@en
P2093
P2860
P356
P1476
How does mild hypothermia affect monoclonal antibody glycosylation?
@en
P2093
Alison Mason
Christopher Sellick
Cleo Kontoravdi
Karen M Polizzi
Sarantos Kyriakopoulos
Si Nga Sou
P2860
P304
P356
10.1002/BIT.25524
P577
2015-04-17T00:00:00Z